Results 191 to 200 of about 42,162 (254)

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

British Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki, Kiplin A. Patanwala, Jan‐Willem C. Alffenaar, Asad E. Patanwala   +3 more
wiley   +1 more source

Safety of tuberculosis-preventive treatment in children aged under 5 years: A rapid review. [PDF]

Rev Soc Bras Med Trop
Uchimura LYT, Yonekura T, Quintans JR, Figueiró MF, Casado KDS, Alves ES, Johansen FDC, Pelissari DM, Souza NM.   +8 more
europepmc   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Quality of life: a neglected aspect in male infertility studies. [PDF]

Int Braz J Urol
Singh A, Esteves SC.
europepmc   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Optimized Milling Approaches for Scalable Production of Ritonavir Nanocrystals: from Process Design to Bioperformance Evaluation

ACS Omega
Marcelo Henrique da Cunha Chaves, Francisco Alexandrino-Júnior, Michelle Alvares Sarcinelli, Natalia Cristina Gomes-da-Silva, Ralph Santos-Oliveira, Fabio Coelho Amendoeira, Helvécio Vinícius Antunes Rocha   +6 more
doaj   +1 more source

Sociodemographic and lifestyle correlates of accelerometer-measured 24-hour physical behavior patterns: a cross-sectional analysis of the ELSA-Brasil cohort. [PDF]

Cad Saude Publica
Vale WSD, Moura BP, Griep RH, Almeida MDCC, Almeida RT, Araujo MC, Fonseca MJMD.   +6 more
europepmc   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Reducing referrals in primary care through specialist-supported telehealth: quasi-experimental evidence from Northeast Brazil. [PDF]

Front Digit Health
Padilha FVQ, de Araújo FAS, Ikawa JNR, Chagas MEV, Kops NL, Hahne FS, Balan VO.   +6 more
europepmc   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source