Results 11 to 20 of about 10,694 (214)

Stabilizing Plasmodium falciparum proteins for small molecule drug discovery. [PDF]

Protein Sci
Abstract Early‐stage drug discovery relies on the availability of stable protein for reliable biophysical characterization of ligand binding. However, many Plasmodium falciparum proteins are challenging to produce in heterologous systems, which limits their experimental utility.
Amann M, Sträßer T, Einsle O, Günther S.   +3 more
europepmc   +2 more sources

Functional networks of the human bromodomain-containing proteins

Frontiers in Bioinformatics, 2022
Background: Bromodomains are a structurally conserved epigenetic reader domain that bind to acetylated lysine residues in both histone and non-histone proteins.
Cong Gao, Karen C. Glass, Karen C. Glass, Seth Frietze, Seth Frietze   +4 more
doaj   +1 more source

Das Kupfertetramminion, ein empfindliches Reagens für CD-Untersuchungen von Kohlenhydraten

CHIMIA, 1973
The circular dichroism spectra of carbohydrate copper tetrammonia solutions allow to get valuable information about the configuration and conformation of sugars.
Wolfgang Voelter, Hermann Bauer, Gisela Kuhfittig   +2 more
doaj   +1 more source

On the Proper Treatment of Dynamics in Cognitive Science

Topics in Cognitive Science, EarlyView., 2023
Abstract This essay examines the relevance of dynamical ideas for cognitive science. On its own, the mere mathematical idea of a dynamical system is too weak to serve as a scientific theory of anything, and dynamical approaches within cognitive science are too rich and varied to be subsumed under a single “dynamical hypothesis.” Instead, after first ...
Randall D. Beer
wiley   +1 more source

Applying multi-omics data to study the genetic background of bovine respiratory disease infection in feedlot crossbred cattle

Frontiers in Genetics, 2022
Bovine respiratory disease (BRD) is the most common and costly infectious disease affecting the wellbeing and productivity of beef cattle in North America. BRD is a complex disease whose development is dependent on environmental factors and host genetics.
Jiyuan Li, Robert Mukiibi, Janelle Jiminez, Zhiquan Wang, Everestus C. Akanno, Edouard Timsit, Graham S. Plastow   +6 more
doaj   +1 more source

Perception, attitude, and practice of labor analgesia among obstetric care providers in Eastern Uttar Pradesh

Asian Journal of Medical Sciences, 2023
Background: Labor pain is among the foremost severe pain that ladies experience in their lifespan, if inadequately treated can lead to certain complications in labor.
Imran Ahmed Khan , Vani Aditya , Arun Kumar Srivastava , DK Srivastava   +3 more
doaj   +1 more source

Efeito da época de colheita e da espessura do tegumento sobre a viabilidade e o vigor de sementes de soja Effects of harvest epoch and seed coat thickness on viability and vigor of soybean seeds

Ciência e Agrotecnologia, 2003
Esta pesquisa foi desenvolvida no Núcleo Experimental de Ciências Agrárias da UFMS, em Dourados, MS, com o objetivo de avaliar a viabilidade e o vigor das sementes de nove genótipos de soja, dos quais, cinco cultivares (EMBRAPA-64, EMBRAPA-4, BR-16, FT ...
Maria Izabel Krüger Giurizatto, Luiz Carlos Ferreira de Souza, Antônio Dias Robaina, Manoel Carlos Gonçalves   +3 more
doaj   +1 more source

Study on Serum Lipoprotein Profile of Exclusive Breast Fed, Mixed Fed and Formula Fed Preterm Infants [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Breast feeding is protective for atherosclerotic cardiovascular disease, obesity, Diabetes Mellitus (DM) and hypertension. Serum lipoprotein is principal risk factor for atherosclerosis. There is growing evidence that risk of Coronary Heart
Vineet Jaiswal, Anita Mehta, Komal Prasad Kushwaha   +2 more
doaj   +1 more source

Limitations of bacterial culture, viral PCR, and tulathromycin susceptibility from upper respiratory tract samples in predicting clinical outcome of tulathromycin control or treatment of bovine respiratory disease in high-risk feeder heifers.

PLoS ONE, 2022
A cross-sectional prospective cohort study including 1026 heifers administered tulathromycin due to high risk of clinical signs of bovine respiratory disease (BRD), measured poor association between BRD clinical outcomes and results of bacterial culture ...
Jeffrey J Sarchet, John P Pollreisz, David T Bechtol, Mitchell R Blanding, Roger L Saltman, Patrick C Taube   +5 more
doaj   +1 more source

Whole-Blood Transcriptome Analysis of Feedlot Cattle With and Without Bovine Respiratory Disease

Frontiers in Genetics, 2021
Bovine respiratory disease (BRD) is one of the main factors leading to morbidity and mortality in feedlot operations in North America. A complex of viral and bacterial pathogens can individually or collectively establish BRD in cattle, and to date, most ...
Janelle Jiminez, Edouard Timsit, Edouard Timsit, Edouard Timsit, Karin Orsel, Frank van der Meer, Le Luo Guan, Graham Plastow   +7 more
doaj   +1 more source