Results 61 to 70 of about 22,571,102 (275)

Tear break-up time in eyes with pterygia and pingueculae in Ibadan

West African Journal of Medicine, 2005
Ultraviolet (UV) rays and chronic irritation to dust have been implicated in the pathogenesis of degenerative conditions of the cornea and conjunctiva like pterygium and pinguecula. It has been postulated that exposure to these environmental factors cause corneal and conjunctival drying by disruption of the tear film.
Balogun, MM, Ashaye, AO, Ajayi, BGK, Osuntokun, OO   +3 more
openaire   +4 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Classification and grading based on Tear film break up time (TBUT) and Schirmer’s test.

, 2022
Classification and grading based on Tear film break up time (TBUT) and Schirmer’s test.
Rudy M. M. A. Nuijts (4433419), Sharon D’Souza (14041049), Abhijit Sinha Roy (14041055), Swaminathan Sethu (220821), Gairik Kundu (14041046), Pooja Khamar (14041052), Rohit Shetty (622288)   +6 more
core   +1 more source

Tea Time: Winter break reflections [PDF]

, 2019
Tea Time discussion on how winter break went.Boston University Howard Thurman Center for Common ...
Boston University Howard Thurman Center for Common Ground
core   +1 more source

Effect of Upper Eyelid Blepharoplasty on Meibomian Gland Morphology

Van Tıp Dergisi
INTRODUCTION: To assess changes in tear film parameters and meibomian gland (MG) morphology after upper eyelid blepharoplasty. METHODS: This prospective observational study included 58 eyes from 29 patients who underwent upper eyelid blepharoplasty ...
Hasan Akgöz, Yunus Emre Erat
doaj   +1 more source

Breaking-up sedentary time is associated with impairment in activities of daily living [PDF]

Experimental Gerontology, 2015
Identifying modifiable behaviors associated with prevention of activities of daily living (ADL) impairments is vital to implement preventive strategies for independent living in elderly. We aimed to examine the associations between objectively measured breaks in sedentary time with ADL impairments and physical independence.
Sardinha, Luis B., Ekelund, Ulf, dos Santos, Leandro, Cyrino, Edilson S., Silva, Analiza M., Santos, Diana A.   +5 more
openaire   +4 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Anterior Segment Optical Coherence Tomography for Tear Meniscus Evaluation and its Correlation with other Tear Variables in Healthy Individuals [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Dry eye is one of the most common ocular diseases in this cyber era. Despite availability of multiple tests, no single test is accurate for the diagnosis of dry eye. Anterior segment optical coherence tomography is the recent tool which
Anuradha Raj, Renu Dhasmana, Ramesh Chander Nagpal   +2 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source