Results 71 to 80 of about 22,571,102 (275)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Possible association between subtypes of dry eye disease and seasonal variation

open access: yesClinical Ophthalmology, 2017
Masahiko Ayaki, Motoko Kawashima, Miki Uchino, Kazuo Tsubota, Kazuno Negishi Department of Ophthalmology, Keio University, Shinjuku, Tokyo, Japan Purpose: The purpose of this study was to evaluate the influence of seasons on the signs and symptoms of ...
Ayaki M   +4 more
doaj  

Impact of Eye Cosmetic Use on Tear Break-up Time in Females: A Comparative Study

open access: yesDelhi Journal of Ophthalmology
Objective: To assess the impact of regular eye cosmetic use on tear film stability in females aged 18–30 years by comparing tear break-up time (TBUT) between cosmetic users and nonusers.
Umesh Belbase   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Keratograph 5M As A Useful And Objective Tool For Evaluating The Ocular Surface In Limbal Stem Cell Deficiency

open access: yesClinical Ophthalmology, 2019
Asunción Alfaro-Juárez,1,* Manuel Caro-Magdaleno,1,2,* Jesús Montero-Iruzubieta,1,2 Ana Fernández-Palacín,3 Ana Muñoz-Morales,1 Manuel Alberto Castilla-Martino,1 Consuelo Spínola-Muñoz,1 Enrique ...
Alfaro-Juárez A   +7 more
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

How do supercontinents break up? — assessing the continental large igneous province (LIP) record of the break-up of Pangea [PDF]

open access: yes, 2012
LIP emplacement is linked to the timing and evolution of supercontinental break-up. LIP-related break-up produces volcanic rifted margins, new and large (up to 108 km2) ocean basins, and new, smaller continents that undergo dispersal and potentially ...
Bryan, Scott Edward, Groflin, Stefan
core  

Modelling dielectric charged drop break up using an energy conservation method

open access: yes, 2008
In the light of experimental evidence a previously published model to predict the charge and mass redistribution when charged dielectric drops break up has been updated. In particular we have taken the dielectric nature of the liquid, the existence of an
Shrimpton, J.S.
core   +1 more source

The break-up of continents and the formation of new ocean basins [PDF]

open access: yes, 2002
Rifted continental margins are the product of stretching, thinning and ultimate break-up of a continental plate into smaller fragments, and the rocks lying beneath them store a record of this rifting process.
Minshull, T.A.
core   +1 more source

Home - About - Disclaimer - Privacy