Results 91 to 100 of about 22,571,102 (275)

Is East Germany Catching Up? A Time Series Perspective [PDF]

open access: yes
This paper assesses whether the economy of East Germany is catching up with the West German region in terms of welfare. While the primary measure for convergence and catching up is per capita output, we also look at other macroeconomic indicators such as
Rolf Scheufele, Bernd Aumann
core  

The comparison between invasive tear break up time and non-invasive tear break up time

open access: yes, 2020
The Invasive Tear Break Up Time (TBUT) and Non-invasive Tear Break Up Time (NIBUT) is compared. Invasive TBUT was measured after the instillation of fluorescein on the tarsal conjunctiva and assessed with Slit Lamp Biomicroscopy (SLB), whereas the NIBUT ...
Jawatankuasa Kerja Management and Science University
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stability of Monetary Unions: Lessons from the Break-up of Czechoslovakia [PDF]

open access: yes
In 1993, Czechoslovakia experienced a two-fold break-up: On January 1, the country disintegrated as a political union, while preserving an economic and monetary union. Then, the Czech-Slovak monetary union collapsed on February 8. We analyze the economic
Fidrmuc, Jan   +2 more
core   +2 more sources

Efficacy and safety of bendazol eye drop atomization in slowing myopia progression in children: A randomized, double-blind, placebo-controlled trial

open access: yesPhotodiagnosis and Photodynamic Therapy
Objective: This study aimed to assess the efficacy and safety of bendazol eye drop atomization in controlling the progression of myopia in children through a randomized, double-blind, placebo-controlled clinical trial.
Airui Xie   +7 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Face Mask and Tear Film Stability: A Pilot Study of the Objective Measurement of Tear Break-Up Time. [PDF]

open access: yesJ Clin Med, 2023
Mohamed-Noriega K   +6 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Investigating Mask-Associated Dry Eye and Contributing Factors in Healthcare Providers

open access: yesClinical Ophthalmology
Kathryn S Park, Bryanna J Lee, Michael J Ang, Medi Eslani, Sarah Shacterman, Jonghwa Jun, Maria L Gomez, Don O Kikkawa, Natalie A Afshari Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California San Diego, San Diego, CA,
Park KS   +8 more
doaj  

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