Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Research aims to calculate income, the break event point, profitability, and sensitivity at a venture grinding fish Bintang Laut. Analysis methods used was a qualitative methodology .Value analysis of income business sector was Rp 10.312.343,17.
Nurul Chairunissa +2 more
doaj +1 more source
Analisis Break Even Point Sebagai Alat Perencanaan Penjualan Pada Tingkat Laba Yang Diharapkan (Studi Kasus Pada Perhutani Plywood Industri Kediri Tahun 2013-2014) [PDF]
This study aims to determine the sales planning on anticipated profit levels and to determine the distribution ot the sales of each product to achieve the expected profit by using analysis Break Even Point.
AR, M. D. (Moch) +2 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Analisis Break Even Point (Bep) Sebagai Alat Perencanaan Laba (Studi Pada CV. Langgeng Makmur Bersama Lumajang Periode 2012-2014) [PDF]
It was trying derive profit maximum survival company to keep going from time to time, good management and efficient is management be able to manage and make decisions useful for survival companies to the porpose.
Andrianto, M. Y. (Muhamad) +2 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
THEORETICAL ASPECTS REGARDING THE TURNOVER ANALYSIS [PDF]
Nowadays, when the economic crisis seems not to be overcome by the authorities it is important for companies to see how they are performing, if their products are sold or not and if it is necessary to take measures according to the results obtained.
CARUNTU ROXANA CORINA
doaj
Economic Efficiency of Bull Fattening Operations in the Czech Republic
Fattened bulls are the main source of beef in the Czech Republic (CR) and in most other EU countries. Profitability of fattening operations is a fundamental prerequisite for increasing domestic beef production.
Jan Syrůček +4 more
doaj +1 more source
LOGISTIC VALUE CHAIN ANALYSIS AS AN APPROACH TO MODELING TOMATO SUPPLY CHAIN NETWORK: STRUCTURAL MARKET EVIDENCE FROM BHARATPUR METROPOLITAN CITY, NEPAL [PDF]
This research established a complete framework for tomato value chain (TVC) analysis, thereby facilitating the modeling of the supply chain. Tomato supply chain in Chitwan district of Nepal, due to disorganized marketing channel is facing enormous ...
Khanal S., Lohani S.
doaj
PENENTUAN BREAK EVEN POINT MELALUI REGRESI DAN NEWTON RAPHSON
Determining Break Even Point (BEP) in a production is an important thing to do. BEP analysis is used as a basis for profit planning. By knowing the Break Even Point (BEP), management can determine the amount of production or sales that must be made according to the profit target to be achieved.
Fitroh Resmi +2 more
openaire +1 more source

