Results 1 to 10 of about 1,852,147 (304)

Time spent above optimal cerebral perfusion pressure is not associated with failure to improve in outcome in traumatic brain injury

Intensive Care Medicine Experimental, 2023
Background Optimal cerebral perfusion pressure (CPPopt) has emerged as a promising personalized medicine approach to the management of moderate-to-severe traumatic brain injury (TBI).
Kevin Y. Stein, Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Younis Ibrahim, Abrar Islam, Izabella Marquez, Fiorella Amenta, Tobias Bergmann, Frederick A. Zeiler   +10 more
doaj   +1 more source

Temporal relationship between vasopressor and sedative administration and cerebrovascular response in traumatic brain injury: a time-series analysis

Intensive Care Medicine Experimental, 2023
Background Although vasopressor and sedative agents are commonly used within the intensive care unit to mediate systemic and cerebral physiology, the full impact such agents have on cerebrovascular reactivity remains unclear.
Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Izabella Marquez, Fiorella Amenta, Kevin Y. Stein, Frederick A. Zeiler   +7 more
doaj   +1 more source

United for health to improve urban food environments across five underserved communities: a cross-sector coalition approach

BMC Public Health, 2022
Background Cross-sector coalitions can be a powerful vehicle to promote adoption and implementation of evidence-based programs and policies across diverse racial/ethnic communities with a high chronic disease burden.
Denise D. Payán, LaVonna B. Lewis, Jacqueline Illum, Breanna Hawkins, David C. Sloane   +4 more
doaj   +1 more source

Monitoring Technologies for HVDC Transmission Lines

Energies, 2023
HVDC transmission systems are becoming more prevalent because of the advantages they offer. They are more efficient and environmentally friendly and are becoming preferred in distributed power generation. The reliable operation of HVDC transmission lines
Jeff Laninga, Ali Nasr Esfahani, Gevindu Ediriweera, Nathan Jacob, Behzad Kordi   +4 more
doaj   +1 more source

Morphological and evolutionary patterns of emerging arctic coastal landscapes: the case of northwestern Nunavik (Quebec, Canada)

Arctic Science, 2020
Northwestern Nunavik (Quebec, Canada) is characterized by specific landforms and poorly documented examples of emerging coastal landscapes. In this study, we identified the different types of coasts and examined how they were morphologically reworked and
Antoine Boisson, Michel Allard
doaj   +1 more source

Optimal bispectral index level of sedation and cerebral oximetry in traumatic brain injury: a non-invasive individualized approach in critical care?

Intensive Care Medicine Experimental, 2022
Background Impaired cerebral autoregulation has been linked with worse outcomes, with literature suggesting that current therapy guidelines fail to significantly impact cerebrovascular reactivity.
Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Carleen Batson, Trevor Slack, Kevin Y. Stein, Francois Mathieu, Frederick A. Zeiler   +7 more
doaj   +1 more source

A novel neuregulin – jagged1 paracrine loop in breast cancer transendothelial migration

Breast Cancer Research, 2018
Background The interaction of breast cancer cells with other cells in the tumor microenvironment plays an important role in metastasis. Invasion and intravasation, two critical steps in the metastatic process, are influenced by these interactions ...
Ramon M. Cabrera, Serena P. H. Mao, Chinmay R. Surve, John S. Condeelis, Jeffrey E. Segall   +4 more
doaj   +1 more source

Geomorphological controls over carbon distribution in permafrost soils: the case of the Narsajuaq river valley, Nunavik (Canada)

Arctic Science, 2020
Soils in the northern circumpolar region play a central role in the global carbon cycle because the release of carbon through permafrost thaw and geomorphological disturbances can potentially cause a feedback on climate.
Samuel Gagnon, Michel Allard
doaj   +1 more source

Non-Invasive Mapping of Cerebral Autoregulation Using Near-Infrared Spectroscopy: A Study Protocol

Methods and Protocols, 2023
The ability of cerebral vessels to maintain a fairly constant cerebral blood flow is referred to as cerebral autoregulation (CA). Using near-infrared spectroscopy (NIRS) paired with arterial blood pressure (ABP) monitoring, continuous CA can be assessed ...
Amanjyot Singh Sainbhi, Nuray Vakitbilir, Alwyn Gomez, Kevin Y. Stein, Logan Froese, Frederick A. Zeiler   +5 more
doaj   +1 more source

Long non-coding RNA ZFAS1 is a major regulator of epithelial-mesenchymal transition through miR-200/ZEB1/E-cadherin, vimentin signaling in colon adenocarcinoma

Cell Death Discovery, 2021
Colon adenocarcinoma is a common cause of cancer-related deaths worldwide. Epithelial-mesenchymal transition is a major regulator of cancer metastasis, and increased understanding of this process is essential to improve patient outcomes.
Stephen J. O’Brien, Casey Fiechter, James Burton, Jacob Hallion, Mason Paas, Ankur Patel, Ajay Patel, Andre Rochet, Katharina Scheurlen, Sarah Gardner, Maurice Eichenberger, Harshini Sarojini, Sudhir Srivastava, Shesh Rai, Theodore Kalbfleisch, Hiram C. Polk, Susan Galandiuk   +16 more
doaj   +1 more source