Results 11 to 20 of about 566,493 (267)

Optimal bispectral index level of sedation and cerebral oximetry in traumatic brain injury: a non-invasive individualized approach in critical care?

open access: yesIntensive Care Medicine Experimental, 2022
Background Impaired cerebral autoregulation has been linked with worse outcomes, with literature suggesting that current therapy guidelines fail to significantly impact cerebrovascular reactivity.
Logan Froese   +7 more
doaj   +1 more source

Negative prices in network pricing games

open access: yesOperations Research Letters, 2022
In a Stackelberg network pricing game, a leader sets prices for a given subset of edges so as to maximize profit, after which one or multiple followers choose a shortest path from their source to sink. We study the counter-intuitive phenomenon that the use of negative prices by the leader may in fact increase his profit.
Andrés Cristi, Marc Schröder 0002
openaire   +4 more sources

Morphological and evolutionary patterns of emerging arctic coastal landscapes: the case of northwestern Nunavik (Quebec, Canada)

open access: yesArctic Science, 2020
Northwestern Nunavik (Quebec, Canada) is characterized by specific landforms and poorly documented examples of emerging coastal landscapes. In this study, we identified the different types of coasts and examined how they were morphologically reworked and
Antoine Boisson, Michel Allard
doaj   +1 more source

Commodity Price Forecasts, Futures Prices, and Pricing Models [PDF]

open access: yesManagement Science, 2019
Even though commodity-pricing models have been successful in fitting the term structure of futures prices and its dynamics, they do not generate accurate true distributions of spot prices. This paper develops a new approach to calibrate these models using not only observations of oil futures prices, but also analysts’ forecasts of oil spot prices.
Gonzalo Cortazar   +3 more
openaire   +2 more sources

A novel neuregulin – jagged1 paracrine loop in breast cancer transendothelial migration

open access: yesBreast Cancer Research, 2018
Background The interaction of breast cancer cells with other cells in the tumor microenvironment plays an important role in metastasis. Invasion and intravasation, two critical steps in the metastatic process, are influenced by these interactions ...
Ramon M. Cabrera   +4 more
doaj   +1 more source

Ramsey prices, average cost prices and price sustainability [PDF]

open access: yesInternational Journal of Industrial Organization, 1986
Abstract We study the relationship between sustainable and average cost prices in the multiproduct case. It is shown that for the case where costs are separable only average cost prices can be sustainable even if demands are interdependent. As for the non-separable cost case the notion of average cost prices is axiomatically defined as an extension ...
Leonard J. Mirman   +2 more
openaire   +2 more sources

Geomorphological controls over carbon distribution in permafrost soils: the case of the Narsajuaq river valley, Nunavik (Canada)

open access: yesArctic Science, 2020
Soils in the northern circumpolar region play a central role in the global carbon cycle because the release of carbon through permafrost thaw and geomorphological disturbances can potentially cause a feedback on climate.
Samuel Gagnon, Michel Allard
doaj   +1 more source

Long non-coding RNA ZFAS1 is a major regulator of epithelial-mesenchymal transition through miR-200/ZEB1/E-cadherin, vimentin signaling in colon adenocarcinoma

open access: yesCell Death Discovery, 2021
Colon adenocarcinoma is a common cause of cancer-related deaths worldwide. Epithelial-mesenchymal transition is a major regulator of cancer metastasis, and increased understanding of this process is essential to improve patient outcomes.
Stephen J. O’Brien   +16 more
doaj   +1 more source

Regulation and pricing of pharmaceuticals: Reference pricing or price cap regulation? [PDF]

open access: yesEuropean Economic Review, 2007
We study the relationship between regulatory regimes and pharmaceutical firms’ pricing strategies using a unique policy experiment from Norway, which in 2003 introduced a reference price (RP) system called “index pricing” for a sub-sample of off-patent pharmaceuticals, replacing the existing price cap (PC) regulation.
Kurt R. Brekke   +2 more
openaire   +5 more sources

Non-Invasive Mapping of Cerebral Autoregulation Using Near-Infrared Spectroscopy: A Study Protocol

open access: yesMethods and Protocols, 2023
The ability of cerebral vessels to maintain a fairly constant cerebral blood flow is referred to as cerebral autoregulation (CA). Using near-infrared spectroscopy (NIRS) paired with arterial blood pressure (ABP) monitoring, continuous CA can be assessed ...
Amanjyot Singh Sainbhi   +5 more
doaj   +1 more source

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