Results 1 to 10 of about 29,744 (154)

Impaired Cerebrovascular Reactivity in Huntington’s Disease [PDF]

Frontiers in Physiology, 2021
There is increasing evidence that impairments of cerebrovascular function and/or abnormalities of the cerebral vasculature might contribute to early neuronal cell loss in Huntington’s disease (HD).
Suk Tak Chan, Nathaniel D. Mercaldo, Kenneth K. Kwong, Steven M. Hersch, Herminia D. Rosas, Herminia D. Rosas   +5 more
doaj   +3 more sources

Neuroimaging assessment of cerebrovascular reactivity in concussion: current concepts, methodological considerations and review of the literature

Frontiers in Neurology, 2016
Concussion is a form of traumatic brain injury (TBI) that presents with a wide spectrum of subjective symptoms and few objective clinical findings. Emerging research suggests that one of the processes that may contribute to concussion pathophysiology is ...
Michael John Ellis, Michael John Ellis, Lawrence eRyner, Lawrence eRyner, Olivia eSobczyk, Olivia eSobczyk, Jorn eFierstra, David eMikulis, David eMikulis, Joseph Arnold Fisher, Joseph Arnold Fisher, James eDuffin, James eDuffin, W. Alan C. Mutch, W. Alan C. Mutch   +14 more
doaj   +1 more source

Cerebrovascular Reactivity and Central Arterial Stiffness in Habitually Exercising Healthy Adults

Frontiers in Physiology, 2018
Reduced cerebrovascular reactivity to a vasoactive stimulus is associated with age-related diseases such as stroke and cognitive decline. Habitual exercise is protective against cognitive decline and is associated with reduced stiffness of the large ...
Kathleen B. Miller, Anna J. Howery, Ronée E. Harvey, Marlowe W. Eldridge, Marlowe W. Eldridge, Jill N. Barnes   +5 more
doaj   +1 more source

Temporal relationship between vasopressor and sedative administration and cerebrovascular response in traumatic brain injury: a time-series analysis

Intensive Care Medicine Experimental, 2023
Background Although vasopressor and sedative agents are commonly used within the intensive care unit to mediate systemic and cerebral physiology, the full impact such agents have on cerebrovascular reactivity remains unclear.
Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Izabella Marquez, Fiorella Amenta, Kevin Y. Stein, Frederick A. Zeiler   +7 more
doaj   +1 more source

The impact of sedative and vasopressor agents on cerebrovascular reactivity in severe traumatic brain injury

Intensive Care Medicine Experimental, 2023
Background The aim of this study is to evaluate the impact of commonly administered sedatives (Propofol, Alfentanil, Fentanyl, and Midazolam) and vasopressor (Dobutamine, Ephedrine, Noradrenaline and Vasopressin) agents on cerebrovascular reactivity in ...
Logan Froese, Emma Hammarlund, Cecilia A. I. Åkerlund, Jonathan Tjerkaski, Erik Hong, Caroline Lindblad, David W. Nelson, Eric P. Thelin, Frederick A. Zeiler   +8 more
doaj   +1 more source

Breath holding for 20 s following extended expiration is a practical, effective and robust standard when measuring cerebrovascular reactivity in healthy adults using BOLD fMRI at 3 T

NeuroImage: Reports, 2021
Background and Purpose: BOLD fMRI is becoming the preferred modality to study cerebrovascular reactivity. Amongst the vasoactive stimuli to induce it, breath holding is considered equal to other methods but both cerebrovascular reserve measures and ...
Jörg Larsen, Kai Kallenberg, Johanna Rühlmann, Jürgen Baudewig, Eike A. Nickel, Michael Knauth, Peter Dechent   +6 more
doaj   +1 more source

Breath holding index in episodic primary headaches [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. Examination of cerebrovascular reactivity in patients with primary headaches is focused mainly on migraine, while the smaller number of studies deals with tensiontype and cluster headache, or comparison of cerebral haemodynamic in ...
Podgorac Ana, Petrušić Igor, Radojičić Aleksandra, Zidverc-Trajković Jasna   +3 more
doaj   +1 more source

Comparison of cerebrovascular reactivity tests: a pilot human study

Journal of Electrical Bioimpedance, 2017
In neurosurgery intensive care units, cerebrovascular reactivity tests for neuromonitoring are used to evaluate the status of cerebral blood flow autoregulation; lack of autoregulation indicates a poor patient outcome.
Bodo Michael, Mahon Richard, Razumovsky Alex, Kouperberg Efim, Crimmins Michael, Armonda Rocco, Baruch Martin   +6 more
doaj   +1 more source

Optimal bispectral index level of sedation and cerebral oximetry in traumatic brain injury: a non-invasive individualized approach in critical care?

Intensive Care Medicine Experimental, 2022
Background Impaired cerebral autoregulation has been linked with worse outcomes, with literature suggesting that current therapy guidelines fail to significantly impact cerebrovascular reactivity.
Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Carleen Batson, Trevor Slack, Kevin Y. Stein, Francois Mathieu, Frederick A. Zeiler   +7 more
doaj   +1 more source

Cerebrovascular pressure reactivity and brain tissue oxygen monitoring provide complementary information regarding the lower and upper limits of cerebral blood flow control in traumatic brain injury: a CAnadian High Resolution-TBI (CAHR-TBI) cohort study

Intensive Care Medicine Experimental, 2022
Background Brain tissue oxygen tension (PbtO2) and cerebrovascular pressure reactivity monitoring have emerged as potential modalities to individualize care in moderate and severe traumatic brain injury (TBI).
Alwyn Gomez, Mypinder Sekhon, Donald Griesdale, Logan Froese, Eleen Yang, Eric P. Thelin, Rahul Raj, Marcel Aries, Clare Gallagher, Francis Bernard, Andreas H. Kramer, Frederick A. Zeiler   +11 more
doaj   +1 more source