Results 41 to 50 of about 445,834 (292)

The aging brain and cerebrovascular reactivity

NeuroImage, 2018
Cerebrovascular reactivity (CVR) is a measure of vascular response to a vasoactive stimulus, and can be used to assess the health of the brain vasculature. In this current study we used different analyses of BOLD fMRI responses to CO2 to provide a number of metrics including ramp and step CVR, speed of response and transfer function analysis (TFA).
Larissa McKetton, Olivia Sobczyk, James Duffin, Julien Poublanc, Kevin Sam, Adrian P. Crawley, Lakshmikumar Venkatraghavan, Joseph A. Fisher, David J. Mikulis   +8 more
openaire   +2 more sources

Cerebrovascular reactivity and white matter integrity [PDF]

Neurology, 2016
To compare the diffusion and perfusion MRI metrics of normal-appearing white matter (NAWM) with and without impaired cerebrovascular reactivity (CVR).Seventy-five participants with moderate to severe leukoaraiosis underwent blood oxygen level-dependent CVR mapping using a 3T MRI system with precise carbon dioxide stimulus manipulation.
Kevin, Sam, Boris, Peltenburg, John, Conklin, Olivia, Sobczyk, Julien, Poublanc, Adrian P, Crawley, Daniel M, Mandell, Lakshmikumar, Venkatraghavan, James, Duffin, Joseph A, Fisher, Sandra E, Black, David J, Mikulis   +11 more
openaire   +2 more sources

Cerebrovascular reactivity in migraineurs

Headache Medicine, 2011
Cerebrovascular reactivity (CR) assessed by transcranial Doppler (TCD) has been evaluated among migraineurs with conflicting results. We assessed the CR using the breath holding index (BHI) among 228 migraineurs during ictal or interictal phase and 56 controls.
Arthur de Carvalho Jatobá e Sousa, Ciro Martins Gomes, Rodolfo de Souza Coelho, Ricardo Afonso Teixeira   +3 more
openaire   +1 more source

Evaluation of cerebrovascular reactivity in chronic hepatitis C patients using transcranial color Doppler.

PLoS ONE, 2019
Hepatitis C viral (HCV) infection is associated with systemic inflammation and metabolic complications that might predispose patients to atherosclerosis, including cerebrovascular atherosclerosis.
Mirela Pavicic Ivelja, Ivo Ivic, Kresimir Dolic, Antonio Mestrovic, Nikola Perkovic, Stipan Jankovic   +5 more
doaj   +1 more source

Dynamic Temporal Relationship Between Autonomic Function and Cerebrovascular Reactivity in Moderate/Severe Traumatic Brain Injury. [PDF]

, 2022
There has been little change in morbidity and mortality in traumatic brain injury (TBI) in the last 25 years. However, literature has emerged linking impaired cerebrovascular reactivity (a surrogate of cerebral autoregulation) with poor outcomes post ...

core   +4 more sources

Associations Between Intracranial Pressure Extremes and Continuous Metrics of Cerebrovascular Pressure Reactivity in Acute Traumatic Neural Injury: A Scoping Review

Neurotrauma Reports
Cerebrovascular pressure reactivity plays a key role in maintaining constant cerebral blood flow. Unfortunately, this mechanism is often impaired in acute traumatic neural injury states, exposing the already injured brain to further pressure-passive ...
Kevin Y. Stein, Fiorella Amenta, Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Younis Ibrahim, Abrar Islam, Tobias Bergmann, Izabella Marquez, Frederick A. Zeiler   +10 more
doaj   +3 more sources

Exercise breaks prevent attenuation in cerebrovascular function following an acute bout of uninterrupted sitting in healthy children

Experimental Physiology, 2023
The purpose of this study was to examine the effect of an acute bout of prolonged sitting with and without exercise breaks on cerebrovascular function in 7‐ to 13‐year‐old children.
Christine M. Tallon, Daniela Nowak‐Flück, Mathew G. Reiger, Daniel J. Green, Mark S. Tremblay, Phil N. Ainslie, Ali M. McManus   +6 more
doaj   +1 more source

Intracranial and Extracranial Injury Burden as Drivers of Impaired Cerebrovascular Reactivity in Traumatic Brain Injury. [PDF]

, 2018
Impaired cerebrovascular reactivity has been associated with outcome following traumatic brain injury (TBI), but it is unknown how it is affected by trauma severity.
Joseph Donnelly, Peter Smielewski, Marek Czosnyka, Basil Nourallah, Eric P. Thelin, Leanne Calviello, Frederick A. Zeiler, Ari Ercole, David K. Menon   +8 more
core   +2 more sources

The effect of age on cerebral blood flow responses during repeated and sustained stand to sit transitions

Physiological Reports, 2020
Introduction Aging is associated with impaired cerebrovascular blood flow and function, attributed to reduced vasodilatory capacity of the cerebrovascular network.
Timo Klein, Tom G. Bailey, Petra Wollseiffen, Stefan Schneider, Christopher D. Askew   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source