Results 61 to 70 of about 2,498,862 (299)

Pendekatan "Break-even Point" Dalam Pemberian Santunan Pasien Rawat Tinggal Di Rumah Sakit Umum Madiun [PDF]

, 1986
Following the study "Cost Analysis of BPDPK members admitted at the Regency Hospitals of Madiun, Ponorogo and Magetan, in 1984" a break-even point (BEP) approach was conducted.
Budiarto, W. (Wasis), Hidayat, W. (Wahyu), Martodipuro, S. (Soebagyo), Soetarmo, R. (Rochjat)   +3 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Financial analysis for custom hire business of mechanical rice transplanter in Bangladesh

Fundamental and Applied Agriculture, 2020
This study was conducted to analyze the financial parameters of a mechanical rice transplanter operation for local service providers and entrepreneurs with hybrid rice variety. Two walking type mechanical rice transplanter of model Daedong DP 480 and DP
Surajit Sarkar, Md. Samiul Basir, Muhammad Ashik E Rabbani, Md. Mosharraf Hossain, Md. Monjurul Alam   +4 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Analisis Break Even Point dan Loan To Deposit Ratio Volume Kredit pada PT Bank Sulut Manado [PDF]

, 2013
Dana sangat berpengaruh dalam manajemen kredit karena makin besar volume dana yang diperoleh, makin besar juga kuantitas volume kredit yang disalurkan kepada masyarakat .
Boroma, J. (Jesi)
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Analisis Titik Pulang Pokok USAha Abon Sapi Pada Industri Rumah Tangga Mutiara Hj Mbok Sri Di Kota Palu [PDF]

, 2013
Beef Abon is made from shredded beef mixed with spices and favorite to all ages, this Abon is very familiar among Indonesian that bring apparently business opportunity to people.
Alam, M. N. (Max), Antara, M. (Made), Pareira, F. E. (Frederikus)   +2 more
core  

Density-matrix simulation of small surface codes under current and projected experimental noise [PDF]

, 2017
We present a full density-matrix simulation of the quantum memory and computing performance of the distance-3 logical qubit Surface-17, following a recently proposed quantum circuit and using experimental error parameters for transmon qubits in a planar ...
DiCarlo, L., O'Brien, T. E., Tarasinski, B.   +2 more
core   +6 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source