Results 41 to 50 of about 6,030,214 (300)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Breakdown of study sample characteristics.

open access: yes, 2019
Breakdown of study sample characteristics.
Sharifa Ameer (6911945)   +4 more
core   +1 more source

Effect of Thickness on the Breakdown Characteristics of Organic Insulation Materials under Microsecond Pulse Voltage

open access: yesEnergies
Thickness affects the electrical breakdown strength (EBD) of insulation materials, and the variation of EBD with thickness (d) is an important basis for insulation design.
Xudong Li   +7 more
doaj   +1 more source

Study on the breakdown characteristics of conductor-plane gap under vegetation fire condition based on the combustion features

open access: yesThe Journal of Engineering, 2019
The frequent forest fires become a serious threat to the performance of transmission lines’ external insulation, therefore, researches on the breakdown characteristics under flame conditions is of great significance for the transmission lines ...
Daochun Huang, Wei Lu, Tao Yao, Peng Li
doaj   +1 more source

Breakdown-limited endurance in HZO FeFETs: Mechanism and improvement under bipolar stress

open access: yesFrontiers in Electronics, 2022
Breakdown is one of main failure mechanisms that limit write endurance of ferroelectric devices using hafnium oxide-based ferroelectric materials.
Kasidit Toprasertpong   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The nanosecond impulsive breakdown characteristics of air, N2 and CO2 in a sub-mm gap [PDF]

open access: yes, 2021
The present paper investigates the breakdown characteristics—breakdown voltage, with breakdown occurring on the rising edge of the applied HV impulses, and time to breakdown—for gases of significance that are present in the atmosphere: air, N2 and CO2 ...
Given, Martin J.   +4 more
core   +1 more source

Significantly Improved Electrical Breakdown Strength of Natural Ester Liquid Dielectrics by Doping Ultraviolet Absorbing Molecules

open access: yesIEEE Access, 2019
In this paper, we experimentally demonstrate that molecules with maximum absorption wavelength corresponding to the first excitation energy of base liquid molecules are able to significantly improve the electrical performances of natural ester oils.
Suning Liang   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Partial discharge breakdown characteristics under needle–plate defect configuration

open access: yesAIP Advances, 2021
Partial discharge of the dielectric is an important problem in fault detection of transmission line systems. It has gained gigantic attention to understand the breakdown characteristics of partial discharge.
Dandan Zou   +2 more
doaj   +1 more source

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