Results 131 to 140 of about 129,534 (273)

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

Multi‐Scale Drivers of Food‐Water‐Energy Related Ecosystem Services in the Context of Land Degradation: Insights From the Beijing‐Tianjin‐Hebei Agglomeration

Land Degradation &Development, EarlyView.
ABSTRACT Land degradation poses significant challenges to maintaining food–water–energy (FWE) security, particularly in rapidly urbanizing regions. The ecosystem services (ES) related to FWE are critical for sustainable regional development. Yet, rapid urbanization in the Beijing–Tianjin–Hebei region has altered land use and ecological patterns ...
Ke Yang, Qi Han, Dujuan Yang
wiley   +1 more source

Targeting the Dynamic Susceptibility Window: Time‐Sensitive Photodynamic Synergy With Antibiotics Against Streptococcus spp

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objective Evaluated the antimicrobial efficacy of curcumin‐mediated photodynamic inactivation (PDI) against both sensitive and resistant strains of Streptococcus pneumoniae and Streptococcus pyogenes, as well as its potential to enhance antibiotic effects (amoxicillin, ceftriaxone, erythromycin).
Isabella S. Gonçalves, Jennifer M. Soares, Vanderlei S. Bagnato, Kate C. Blanco   +3 more
wiley   +1 more source

From maps to mandates: Multitemporal vegetation cover analysis as a tool to evaluate environmental judicial decisions

People and Nature, EarlyView.
Abstract This study examines the use of multitemporal vegetation cover analysis as a tool to assess the ecological effectiveness of judicial decisions that recognize the rights of nature, using Colombia's 2016 T‐622 decision on the Atrato River as a case study.
Juan Camilo Ríos‐Orjuela, Ana María Medina‐Sánchez, William Gonzalez‐Daza, Francisco Villa‐Rojas, Mauricio Madrigal‐Pérez   +4 more
wiley   +1 more source

DeepECC: a deep learning framework for genome-wide identification and analysis of human cancer eccDNAs. [PDF]

Nucleic Acids Res
Wang C, Xu Y, Li R, Qiang M, Guo C, He Q, Wu X, Hou L, Xu Q, Xu Y.   +9 more
europepmc   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

Injury Risks to a Migratory Freshwater Fish During Downstream Passage Through a Regulated Floodplain Outlet: A Case Study on Golden Perch (Macquaria ambigua)

River Research and Applications, EarlyView.
ABSTRACT River infrastructures such as weirs, dams, inlet and outlet regulators often impair connectivity, leading to degradation and loss of key habitats for riverine fishes. This also holds true for golden perch (Macquaria ambigua Richardson), a migratory species in Australia's Murray–Darling Basin.
Josef Knott, Craig A. Boys, Christoffer Nagel, Jason D. Thiem, Lee J. Baumgartner, Juergen Geist   +5 more
wiley   +1 more source

Pan-European analysis shows stable, low antimicrobial resistance in most bovine and porcine respiratory tract pathogens. [PDF]

Front Microbiol
de Jong A, Temmerman R, Rose M, Simjee S, El Garch F, VetPath Study Group.   +5 more
europepmc   +1 more source

Evaluating methods for high‐resolution, national‐scale seagrass mapping in Google Earth Engine

Remote Sensing in Ecology and Conservation, EarlyView.
Marine habitat mapping using satellite imagery can provide baseline and monitoring data across large spatial scales and in remote locations globally. This study evaluates how key methodological choices influence the accuracy of open‐source (for non‐commercial use), cloud‐based satellite mapping workflows for seagrass meadows in the Maldives.
Matthew Floyd, Holly K. East, Andrew J. Suggitt   +2 more
wiley   +1 more source

A breakage-replication/fusion process explains complex rearrangements and segmental DNA amplification. [PDF]

Nat Genet
Zhang CZ, Mendez-Dorantes C, Burns KH, Pellman D.   +3 more
europepmc   +1 more source