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Antimicrobial Susceptibility Testing: A Comprehensive Review of Currently Used Methods

Antibiotics, 2022
Antimicrobial resistance (AMR) has emerged as a major threat to public health globally. Accurate and rapid detection of resistance to antimicrobial drugs, and subsequent appropriate antimicrobial treatment, combined with antimicrobial stewardship, are ...
Dusan Kekic, Ina Gajić, Anika Trudić   +2 more
exaly   +3 more sources

How to accelerate antimicrobial susceptibility testing [PDF]

Clinical Microbiology and Infection, 2019
Antimicrobial susceptibility testing (AST) results are crucial for timely administration of effective antimicrobial treatment, and, thus, should be made available to clinicians as fast as possible. In particular, increasing rates of multidrug-resistant organisms emphasize the need for rapid AST (rAST).This article aims to provide microbiologists and ...
Karsten Becker, E A Idelevich
exaly   +3 more sources

Identification and Antimicrobial Susceptibility Testing Performance for Short Incubation of Gram-Negative Pathogens from Bloodstream Infections at a Tertiary Care Center in Telangana [PDF]

Journal of Pharmacy and Bioallied Sciences
Background and Objectives: Blood culture is the “gold standard” for diagnosing bacteremia. This study evaluates the performance of shortened incubation cultures in pathogen identification (ID) and antimicrobial susceptibility testing (AST) using the ...
Neelima Sudharshan, Sayeeda Munawar, MVNL Ram Mohan, SD Fatima Tasneem, C Padmasri, P Umabala, C Sudharshan Raj   +6 more
doaj   +2 more sources

Point of care antimicrobial susceptibility testing. [PDF]

Eur J Clin Microbiol Infect Dis
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Couwenberg J, van Belkum A, van de Kerkhof D, Scharnhorst V, Wertheim H, van der Linden A, van Asten S.   +6 more
europepmc   +4 more sources

Clinical evaluation of EUCAST rapid antimicrobial susceptibility testing in Gram-negative bacilli bloodstream infections: a real-world retrospective study [PDF]

Frontiers in Microbiology
Background/ObjectivesRapid antimicrobial susceptibility testing (RAST) performed directly from positive blood cultures may facilitate earlier optimization of antimicrobial therapy in bloodstream infections.
Peng-Peng Tian, Hua-Wei Yi, Hua-Wei Yi, Tian Wang, Hui Yang, Meng-Yao Du, Li-Sha Zhu, Xian-Mo Wang, Liang-Cai Xie, Li Wan, Tian Tian   +10 more
doaj   +2 more sources

Antimicrobial Susceptibility Testing of Antimicrobial Peptides to Better Predict Efficacy

Frontiers in Cellular and Infection Microbiology, 2020
During the development of antimicrobial peptides (AMP) as potential therapeutics, antimicrobial susceptibility testing (AST) stands as an essential part of the process in identification and optimisation of candidate AMP.
Maren von Köckritz-Blickwede, Derry K Mercer, Searle Duay   +2 more
exaly   +3 more sources

Phenotypic and genomic characterization of Roseomonas mucosa, an opportunistic pathogen with discrepancies among antimicrobial susceptibility testing methods [PDF]

Antimicrobial Agents and Chemotherapy
Roseomonas mucosa is an opportunistic bacterium found in clinical and environmental samples that primarily affects immunocompromised patients. Treatment is challenging owing to the lack of standardized susceptibility testing methods, breakpoints, and ...
Camille Cotet, Sebastien Galopin, Anne-Emeline Creach, Marwan Tenouri, Charlotte Le Pont, Nathalie Laquay, Jean-Christophe Giard, Simon Le Hello, François Gravey   +8 more
doaj   +2 more sources

Rapid antimicrobial susceptibility testing in patients with bacteraemia due to Enterobacterales: an implementation study

Swiss Medical Weekly, 2023
AIMS OF THE STUDY: The goal of this descriptive study was to assess the performance as well as the extent of the clinical impact of rapid automated antimicrobial susceptibility testing in patients with bacteraemia due to Enterobacterales.
Claudine Reiber, Elias Bodendoerfer, Silvio D. Brugger, Nadia Eberhard, Eva Hitz, Daniel A. Hofmaenner, Sebastian Herren, Natalia Kolesnik-Goldmann, Stefano Manicini, Reinhard Zbinden, Annelies S. Zinkernagel, Barbara Hasse   +11 more
doaj   +1 more source

EUCAST v.12.0 Review Focused on Changes

Annals of Clinical Microbiology, 2022
Clinical and Laboratory Standards Institute and European Committee on Antimicrobial Susceptibility Testing (EUCAST) clinical breakpoint tables are commonly used as guidelines for the interpretation of antimicrobial susceptibility testing results.
Sae Am Song
doaj   +1 more source

Same day identification and full panel antimicrobial susceptibility testing of bacteria from positive blood culture bottles made possible by a combined lysis-filtration method with MALDI-TOF VITEK mass spectrometry and the VITEK2 system. [PDF]

PLoS ONE, 2014
Rapid identification and antimicrobial susceptibility testing of microorganisms causing bloodstream infections or sepsis have the potential to improve patient care. This proof-of-principle study evaluates the Lysis-Filtration Method for identification as
Alexandra Machen, Tim Drake, Yun F Wayne Wang   +2 more
doaj   +1 more source