Comparison between EUCAST Broth Microdilution and MIC Strip Test in Defining Isavuconazole In Vitro Susceptibility against Candida and Rare Yeast Clinical Isolates [PDF]
Isavuconazole is a new broad-spectrum triazole, with significant in vitro activity against yeasts. Isavuconazole in vitro susceptibility can be evaluated through broth microdilution as a reference method.
Maddalena Calvo +4 more
doaj +3 more sources
A Pragmatic Approach to Susceptibility Classification of Yeasts without EUCAST Clinical Breakpoints
EUCAST has established clinical breakpoints for the six most common Candida species and Cryptococcus neoformans but not for less common yeasts because sufficient evidence is lacking. Consequently, the question “How to interpret the MIC?” for other yeasts
Sevtap Arikan-Akdagli +2 more
exaly +4 more sources
Interpretation of Antimicrobial Susceptibility Testing Using European Committee on Antimicrobial Susceptibility Testing (EUCAST) and Clinical and Laboratory Standards Institute (CLSI) Breakpoints: Analysis of Agreement [PDF]
Objectives: Breakpoints provided by European Committee on Antimicrobial Susceptibility Testing (EUCAST) are now being used in many countries. This study was planned to ascertain the agreement in antimicrobial susceptibility using the Clinical and ...
Priyanka Gaur +5 more
openalex +2 more sources
Estudo comparativo entre as metodologias preconizadas pelo CLSI e pelo EUCAST para avaliação da atividade antifúngica Comparative study of the recommended methodologies by CLSI and EUCAST for activity evaluation antifungal [PDF]
The international organizations CLSI and EUCAST developed reference methodologies for activity evaluation antifungal. The aim of this work was to compare the recommended methodologies by the CLSI and EUCAST in the antifungal activity evaluation of crude ...
Marcos Aurélio Stoppa +6 more
doaj +2 more sources
Background We previously reported an increase in meropenem prescriptions for Pseudomonas aeruginosa infections in our hospital after the implementation of the 10th version of the EUCAST breakpoints table for P. aeruginosa in January 2020.
Aline Munting +5 more
doaj +2 more sources
Development and preliminary validation of a modified EUCAST yeast broth microdilution MIC method with Tween 20-supplemented medium for rezafungin [PDF]
BACKGROUND Rezafungin is a novel, once-weekly echinocandin. EUCAST rezafungin MIC testing has been associated with a good separation of WT and target gene mutant isolates in single-centre studies, but an unacceptable inter-laboratory MIC variation has ...
Douglas E. Zuill +4 more
openalex +2 more sources
Multicenter evaluation of low inoculum and a colorimetric assay for antifungal susceptibility testing of Aspergillus fumigatus to echinocandins with the EUCAST E.Def 9.4 [PDF]
Echinocandin minimal effective concentration (MEC) determination for Aspergillus is challenging with the EUCAST method. We investigated the applicability of a lower inoculum (103 CFU/mL) and a colorimetric assay for micafungin and anidulafungin against ...
Joseph Meletiadis +5 more
doaj +2 more sources
Comparison of ceftobiprole 5 μg disk diffusion, MIC test strip, and broth microdilution for susceptibility testing of Staphylococcus aureus clinical isolates [PDF]
Ceftobiprole is a new-generation cephalosporin with activity against Staphylococcus aureus, but a comprehensive evaluation of MIC Test Strip (MTS) and disk diffusion (DD) methods using EUCAST and FDA breakpoint is lacking. Using broth microdilution (BMD)
Xinying Wang +4 more
doaj +2 more sources
Antimicrobial susceptibility testing of Aggregatibacter Actinomycetemcomitans can be performed using the EUCAST medium for anaerobic bacteria [PDF]
Background The oral bacterium Aggregatibacter actinomycetemcomitans (Aa) is associated with infectious diseases treated with antibiotics, but specific recommendations for antimicrobial susceptibility testing (AST) of the species do not yet exist ...
Anne Birkeholm Jensen +3 more
doaj +2 more sources
Comparative assessment of the broth microdilution and VITEK 2 systems for antifungal susceptibility testing of Candida auris (Candidozyma auris) Isolates [PDF]
Background Candidozyma auris is a multidrug resistant fungal pathogen classified by the World Health Organization (WHO) as a critical priority species.
Ozlem Aydemir +6 more
doaj +2 more sources

