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Antifungal Susceptibility Testing: A Primer for Clinicians [PDF]
Open Forum Infectious Diseases, 2021 Abstract Clinicians treating patients with fungal infections may turn to susceptibility testing to obtain information regarding the activity of different antifungals against a specific fungus that has been cultured. These results may then be used to make decisions regarding a patient’s therapy.
Nathan P Wiederhold
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Antifungal Susceptibility Testing: Current Approaches [PDF]
Clinical Microbiology Reviews, 2020 Although not as ubiquitous as antibacterial susceptibility testing, antifungal susceptibility testing (AFST) is a tool of increasing importance in clinical microbiology laboratories. The goal of AFST is to reliably produce MIC values that may be used to guide patient therapy, inform epidemiological studies, and track rates of antifungal ...
Elizabeth L Berkow +2 more
exaly +5 more sources
Can We Improve Antifungal Susceptibility Testing? [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Systemic antifungal agents are increasingly used for prevention or treatment of invasive fungal infections, whose prognosis remains poor. At the same time, emergence of resistant or even multi-resistant strains is of concern as the antifungal arsenal is ...
Charlotte Durand +8 more
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Susceptibility Testing of Fungi to Antifungal Drugs [PDF]
Journal of Fungi, 2018 Susceptibility testing of fungi against antifungal drugs commonly used for therapy is a key component of the care of patients with invasive fungal infections.
Maurizio Sanguinetti, Brunella Posteraro
doaj +4 more sources
Medical Journal of Dr. D.Y. Patil University, 2015 Late onset of fungal sepsis in very low birth weight (VLBW) infants is common and has a high mortality and morbidity. Many of these infants were also receiving fluconazole prophylaxis.
Shilpee Raturi +2 more
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Clinical utility of antifungal susceptibility testing. [PDF]
JAC Antimicrob Resist, 2022 Abstract Invasive fungal diseases cause significant morbidity and mortality, in particular affecting immunocompromised patients. Resistant organisms are of increasing importance, yet there are many notable differences in the ability to both perform and interpret antifungal susceptibility testing compared with bacteria. In this review, we
McCarty TP +3 more
europepmc +3 more sources
A Practical Guide to Antifungal Susceptibility Testing. [PDF]
J Pediatric Infect Dis Soc, 2023 We review antifungal susceptibility testing and the development of clinical breakpoints, and detail an approach to using antifungal susceptibility results when breakpoints have not been defined. This information may prove helpful when selecting therapy for invasive fungal infections in children.
Otto WR, Arendrup MC, Fisher BT.
europepmc +4 more sources
Standardization of antifungal susceptibility testing [PDF]
Journal of Antimicrobial Chemotherapy, 1996 The application of in-vitro antifungal susceptibility testing to clinical research and to the guidance of antifungal therapy has been limited by a lack of reproducibility and uncertain clinical relevance. As a result of studies of the identified variables impacting on in-vitro susceptibility results, the National Committee for Clinical Laboratory ...
Martin Cormican, Michael A. Pfaller
openalex +4 more sources
Antifungal Susceptibility Testing Experience in the Management of Culture-Positive Mucormycosis: Observation from a Large Healthcare System [PDF]
Journal of FungiBackground: Mucormycosis, an invasive fungal infection with high morbidity and mortality rates, requires prompt surgical and antifungal therapies; however, the role of antifungal susceptibility testing (AFST) in clinical management of mucormycosis ...
Maryam Naveed +4 more
doaj +2 more sources
Indian Journal of Pathology and Microbiology, 2014 With the increase in invasive fungal infections due to Candida species and resistance to antifungal therapy, in vitro antifungal susceptibility testing is becoming an important part of clinical microbiology laboratories.
Sidhartha Giri, Anupma Jyoti Kindo
doaj +2 more sources