Establishing the reference broth microdilution MIC method for cefepime-taniborbactam [PDF]
The investigational β-lactam/β-lactamase inhibitor combination cefepime-taniborbactam is intended as therapy for serious infections caused by Gram-negative pathogens resistant to third-generation cephalosporins and carbapenems.
Adam Belley +7 more
doaj +5 more sources
The impact of commercially available media on cefiderocol susceptibility testing by broth microdilution method [PDF]
The reference method for determining cefiderocol MIC is broth microdilution (BMD) using iron-depleted cation-adjusted Mueller–Hinton broth (ID-CAMHB). However, laboratories have reported variable MIC findings and difficulties in determining MIC endpoints.
Christopher Longshaw +2 more
exaly +3 more sources
Standartization of broth microdilution method for Mycobacterium tuberculosis [PDF]
Indirect drug susceptibility tests of Mycobacterium tuberculosis was done to investigate the accuracy and feasibility of a broth microdilution method (BMM) for determining minimal inhibitory concentrations of conventional drugs against M.
Clarice Queico Fujimura Leite +3 more
doaj +6 more sources
Development of a Broth Microdilution Method for Exebacase Susceptibility Testing
Exebacase (CF-301) belongs to a new class of protein-based antibacterial agents, known as lysins (peptidoglycan hydrolases). Exebacase, a novel lysin with antistaphylococcal activity, is in phase 3 of clinical development.
J. Oh, J. Ambler, C. Cassino, R. Schuch
semanticscholar +3 more sources
Drug susceptibility testing of Mycobacterium tuberculosis by the broth microdilution method with 7H9 broth [PDF]
In this study, we have evaluated the broth microdilution method (BMM) for susceptibility testing of Mycobacterium tuberculosis. A total of 43 clinical isolates of M. tuberculosis and H37Rv as a control strain were studied. All isolates were tested by the
Ahmet Yilmaz Coban +3 more
doaj +4 more sources
Antimicrobial susceptibility testing of anaerobes is challenging. Because MIC determination is recommended by both CLSI and EUCAST, commercial broth microdilution and diffusion strip tests have been developed.
Florian Baquer +6 more
doaj +2 more sources
Variability of Beta-Lactam Broth Microdilution for Pseudomonas aeruginosa
Antimicrobial susceptibility testing for Pseudomonas aeruginosa is critical to determine suitable treatment options. Commercial susceptibility tests are typically calibrated against the reference method, broth microdilution (BMD).
A. A. Bhalodi +3 more
semanticscholar +3 more sources
Validation of a method of broth microdilution for the determination of antibacterial activity of essential oils [PDF]
Objective The aim of the present study was to adapt and optimize a broth microdilution method and compare it to the agar dilution method for the evaluation of activity of essential oils from medicinal plants against Gram-negative bacteria.
Vanegas David +8 more
semanticscholar +5 more sources
A multicenter performance evaluation of cefiderocol MIC results: ComASP in comparison to CLSI broth microdilution [PDF]
The performance of the Liofilchem Compact Antimicrobial Susceptibility Panel (ComASP) Cefiderocol was evaluated in a multicenter study. Enterobacterales, Acinetobacter baumannii, and Pseudomonas aeruginosa clinical isolates and challenge isolates were ...
L. M. Koeth +7 more
doaj +2 more sources
The objective of this research was to evaluate the correlation between inhibitory zones and MIC when testing ceftazidime-avibactam using disk diffusion, Etest, and broth microdilution method established by the Clinical and Laboratory Standards Institute (
Xuelin Yang, Dandan Yin, Li Ding
exaly +3 more sources

