Detection of mecC-Methicillin-resistant Staphylococcus aureus isolates in river water : a potential role for water in the environmental dissemination [PDF]
Methicillin-resistant Staphylococcus aureus (MRSA) is a public health concern due to limited treatment options. The recent description of a mecA homologue, mecC in human and cattle, led to studies to detect this new variant in human and other animal ...
Concepcion Porrero, M. +12 more
core +2 more sources
Background Considering the increasing use of polymyxins to treat infections due to multidrug resistant Gram-negative in many countries, it is important to evaluate different susceptibility testing methods to this class of antibiotic.
Fung Liang +7 more
doaj +1 more source
Anthracimycin activity against contemporary methicillin-resistant Staphylococcus aureus. [PDF]
Anthracimycin is a recently discovered novel marine-derived compound with activity against Bacillus anthracis. We tested anthracimycin against an expanded panel of Staphylococcus aureus strains in vitro and in vivo. All strains of S.
Cunningham, Mark L +12 more
core +1 more source
CLSI broth microdilution method for testing susceptibility of Malasseziapachydermatis to thiabendazole [PDF]
Thiabendazole, classified as antiparasitic and also used as an antifungal drug, can be found as otological solution indicated for treatment of parasitic and fungal external otitis in small animals. Malassezia pachydermatis is a yeast recognized as a normal inhabitant on the skin and mucous membranes of dogs and cats.
Nascente, Patrícia da Silva +5 more
openaire +5 more sources
Background: The broth disk elution (BDE) method has been recommended by CLSI as an alternative to the broth microdilution (BMD) method, which is the reference method for determining the colistin susceptibility of Gram-negative bacteria, since it is more ...
Tuğba Ayvalık, Emel Sesli Çetin
doaj +1 more source
Single dose pharmacodynamics of amphotericin B against Aspergillus species in an in vitro pharmacokinetic/pharmacodynamic model [PDF]
Conventional MIC testing of amphotericin B results in narrow MIC ranges challenging the detection of resistant strains. In order to discern amphotericin B pharmacodynamics, the in vitro activity of amphotericin B was studied against Aspergillus isolates ...
Al-Saigh, Rafal +5 more
core +1 more source
Torulopsis glabrata: azole susceptibilities by microdilution colorimetric and macrodilution broth assays [PDF]
Fluconazole and itraconazole MICs were determined by both the standard macrodilution method of the National Committee for Clinical Laboratory Standards and a colorimetric broth microdilution method for 140 isolates of Torulopsis (Candida) glabrata obtained over a 15-year period.
R N, Tiballi +3 more
openaire +2 more sources
Review of Colistin Susceptibility Testing with Current Data
Polymyxin E is the main drug used in the treatment of microorganisms with multidrug resistance. The positively charged nature of colistin creates difficulties in susceptibility testing.
Yasemin NADİR, Ayşe Alga BATIREL
doaj +1 more source
Sepsis caused by bloodstream infection in patients in the intensive care unit: the impact of inactive empiric antimicrobial therapy on outcome [PDF]
Background: Sepsis is one of the leading causes of death in the UK. Aims: The aims of this study were to identify the rate of inactive antimicrobial therapy (AMT) in the ICU and whether inactive AMT had an effect on in hospital mortality, ICU ...
Booth, M.G. +4 more
core +1 more source
Discordance of vancomycin minimum inhibitory concentration for methicillin-resistant Staphylococcus aureus at 2 μg/mL between Vitek II, E-test, and Broth Microdilution [PDF]
Background Vancomycin, the first line antibiotic for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, is often administered inappropriately when MIC is greater than 2 µg/mL, including ‘susceptible’ strains.
Chien-Feng Kuo +7 more
doaj +2 more sources

