Results 51 to 60 of about 157,032 (265)

BioEISense: A Microfluidic Platform for Real‐Time Monitoring of Staphylococcus aureus Biofilm Formation and the Efficacy of Antibiofilm Agents

Advanced Materials Interfaces, EarlyView.
BioEISense is a microfluidic device with integrated impedance sensors, for real‐time, label‐free monitoring of S. aureus biofilms. In this study, the biofilm culture conditions were optimized to support sensitive and reproducible detection of biofilm formation and eradication under dynamic flow‐through conditions. The system was also validated for both
Jéssica Amorim, Laura Vesalainen, Loïc Dreano, Markus Haapala, Cristina D. Cruz, Päivi Tammela, Tiina M. Sikanen   +6 more
wiley   +1 more source

Evaluation of the Etest and disk diffusion method for detection of the activity of ceftazidime-avibactam against Enterobacterales and Pseudomonas aeruginosa in China

BMC Microbiology, 2020
Background Ceftazidime-avibactam was approved in China in 2019 for treating complicated intra-abdominal infections, hospital-acquired pneumonia, ventilator-associated pneumonia, and infections caused by Enterobacterales and Pseudomonas aeruginosa for ...
Qi Wang, Feifei Zhang, Zhanwei Wang, Hongbin Chen, Xiaojuan Wang, Yawei Zhang, Shuguang Li, Hui Wang   +7 more
doaj   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

Estudo comparativo de técnicas de screening para avaliação da atividade anti-bacteriana de extratos brutos de espécies vegetais e de substâncias puras Comparative study of screening techniques for antibacterial activity evaluation of plant crude extracts and pure compounds

Química Nova, 2008
In this work, the effectiveness of four screening techniques (three techniques of the diffusion method and one microdilution broth method) were compared.
Everton Giovanni Alves, Adriana Helena Chicharo Vinholis, Luciana Assirati Casemiro, Niege Araçari Jacometti Cardoso Furtado, Márcio Luis Andrade e Silva, Wilson Roberto Cunha, Carlos Henrique Gomes Martins   +6 more
doaj   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

A Clinico-microbiological Approach to Dermatophytosis with Special Reference to Antifungal Susceptibility to the Commonly Used Antifungal Agents: A Prospective Study

Archives of Medicine and Health Sciences
Background and Aim: Dermatophytosis is one of the common cutaneous infections in humans, and due to the increasing prevalence of dermatophytosis in the clinical setup, there is an urgent need to diagnose and treat dermatophytosis appropriately with due ...
Nazneen Yousuf, Tariq Ahmad Shah, Vidya Pai   +2 more
doaj   +1 more source

Comparative Evaluation of VITEK 2 and Broth Microdilution Methods for Colistin Antimicrobial Susceptibility Test

Namık Kemal Tıp Dergisi, 2020
Aim:Accurate susceptibility testing methods are needed for colistin. In our study, we aimed to determine the efficacy of VITEK 2 (bioMérieux, Marcy-L’Etoile, France) in detecting colistin sensitivity by comparing the broth microdilution method with VITEK
Birol ŞAFAK, Özge TOMBAK, Aynur EREN TOPKAYA   +2 more
doaj   +1 more source

Antibiotic susceptibility pattern of Portuguese environmental Legionella isolates

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionLegionnaires’ Disease is a pneumonia caused by Legionella spp., currently treated empirically with fluoroquinolones and macrolides. In this study, we aim to describe the antibiotic susceptibility pattern of environmental Legionella recovered ...
Carolina Cruz, Lúcia Rodrigues, Filipa Fernandes, Ricardo Santos, Paulo Paixão, Maria Jesus Chasqueira   +5 more
doaj   +1 more source

Torulopsis glabrata: azole susceptibilities by microdilution colorimetric and macrodilution broth assays [PDF]

Journal of Clinical Microbiology, 1995
Fluconazole and itraconazole MICs were determined by both the standard macrodilution method of the National Committee for Clinical Laboratory Standards and a colorimetric broth microdilution method for 140 isolates of Torulopsis (Candida) glabrata obtained over a 15-year period.
R N, Tiballi, L T, Zarins, X, He, C A, Kauffman   +3 more
openaire   +2 more sources

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source