Itraconazole, Voriconazole, and Posaconazole CLSI MIC Distributions for Wild-Type and Azole-Resistant Aspergillus fumigatus Isolates [PDF]
Journal of Fungi (Basel, Switzerland), 2018 Azole resistance in Aspergillus fumigatus is most frequently conferred by mutations in the cyp51A gene encoding 14α-sterol demethylases. TR34/L98H and TR46/Y121F/T289A are the two most common mutations associated with environmental resistance ...
Anuradha Chowdhary +2 more
exaly +6 more sources
Change of antibiotic susceptibility testing guidelines from CLSI to EUCAST: influence on cumulative hospital antibiograms. [PDF]
PLoS ONE, 2013 OBJECTIVE:We studied whether the change in antibiotic susceptibility testing (AST) guidelines from CLSI to EUCAST influenced cumulative antibiograms in a tertiary care hospital in Switzerland. METHODS:Antibiotic susceptibilities of non-duplicate isolates
Aline Wolfensberger +5 more
doaj +3 more sources
Comparison of clinical antibiotic susceptibility testing interpretations to CLSI standard interpretations [PDF]
Antimicrobial Stewardship & Healthcare Epidemiology, 2023 Background: Clinical antibiotic susceptibility testing (AST) interpretations based on minimum inhibitory concentrations (MIC) breakpoints are important for both clinical decision making and some reportable condition criteria.
Erin Hitchingham +3 more
doaj +2 more sources
Understanding and Addressing CLSI Breakpoint Revisions: a Primer for Clinical Laboratories. [PDF]
Journal of Clinical Microbiology, 2019 The Clinical and Laboratory Standards Institute (CLSI) has revised several breakpoints since 2010 for bacteria that grow aerobically. In 2019, these revisions include changes to the ciprofloxacin and levofloxacin breakpoints for the Enterobacteriaceae and Pseudomonas aeruginosa , daptomycin ...
Romney M Humphries, Janet A Hindler
exaly +3 more sources
Molecular analysis of metallo-β-lactamase genes in some gram-negative bacteria and examination of the phylogenetic relationships of isolates [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2022 Aim: This study aimed to determine the susceptibility of carbapenem-resistant Gr (-) bacilli isolated from various clinical infections to various antibiotics and identify genes causing carbapenem resistance and their clonal relationships to elucidate the
Farzad Heydari +3 more
doaj +1 more source
Alcohol Used as Disinfectant before Venipuncture does not Lead to Sample Haemolysis or Sample Dilution [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Sample haemolysis is often the leading cause of sample rejections in clinical laboratory. Isopropyl alcohol or ethyl alcohol, used as disinfectant during sample collection is often considered an important cause of sample haemolysis or ...
Devajit Sarmah +3 more
doaj +1 more source
Journal of Contemporary Medicine, 2022 Objective: Staphylococci cause community-acquired and hospital-acquired infections, and Staphylococcus aureus is one of leading agents. In the last decades methicillin-resistant S.aureus (MRSA), vancomycin-intermediate S.aureus (VISA) and vancomycin ...
Muradiye Yarar +5 more
doaj +1 more source
Prevalence and Molecular Characterization of MRSA Isolates from Pus and Blood Samples with Special Reference to MecA and ErmA Gene at a Tertiary care in Kanpur [PDF]
Al Ameen Journal of Medical Sciences, 2023 Background: Methicillin-resistant staphylococci are now recognized as a major cause of infectious diseases, particularly in hospitals. Molecular epidemiology is important for prevention and control of infection.
Shruti Sinha +3 more
doaj
Microbiology Spectrum, 2023 The aim of this study was to evaluate the correlation between inhibitory zones and minimum inhibitory concentrations (MICs) when testing cefiderocol against Acinetobacter baumannii complex using disk diffusion and the broth microdilution (BMD) method ...
Yanling Liu +6 more
doaj +1 more source
Journal of Global Antimicrobial Resistance, 2021 : Objectives: : Manogepix, the active moiety of the prodrug fosmanogepix, is a novel antifungal with activity against major fungal pathogens including Candida (except Candida krusei), Aspergillus and difficult-to-treat/rare moulds.
Michael A. Pfaller +4 more
doaj +1 more source