Results 31 to 40 of about 129,534 (273)

Accurate Jitter Computation in CNA Breakpoints Using Hybrid Confidence Masks With Applications to SNP Array Probing

IEEE Access, 2018
Chromosomal structural changes known as copy number alterations-aberrations (CNAs) result in gains or losses in copies of deoxyribonucleic acid sections, which are typically associated with different types of cancer. An intensive noise inherent to modern
Jorge Munoz-Minjares, Yuriy S. Shmaliy, Luis J. Morales-Mendoza, Miguel Vazquez-Olguin, Carlos Lastre-Dominguez   +4 more
doaj   +1 more source

Distance Oracles for Time-Dependent Networks [PDF]

, 2014
We present the first approximate distance oracle for sparse directed networks with time-dependent arc-travel-times determined by continuous, piecewise linear, positive functions possessing the FIFO property.
A. Orda, B.C. Dean, D. Delling, E. Porat, F. Dehne, G. Nannicini, H.D. Sherali, K. Cooke, M. Thorup, S.E. Dreyfus   +9 more
core   +3 more sources

Trends and controls of terrestrial gross primary productivity of China during 2000–2016

Environmental Research Letters, 2019
Terrestrial gross primary productivity (GPP) is an important flux that drives the global carbon cycle. However, quantifying the trend and the control factor of GPP from the pixel level to the regional level is still a challenge.
Jun Ma, Xiangming Xiao, Renhui Miao, Yao Li, Bangqian Chen, Yao Zhang, Bin Zhao   +6 more
doaj   +1 more source

In vitro Activity of Cefiderocol and Comparators against Carbapenem-Resistant Gram-Negative Pathogens from France and Belgium

Antibiotics, 2022
Infections with carbapenem-resistant (CR) Gram-negative (GN) pathogens have increased in many countries worldwide, leaving only few therapeutic options.
Saoussen Oueslati, Pierre Bogaerts, Laurent Dortet, Sandrine Bernabeu, Hend Ben Lakhal, Christopher Longshaw, Youri Glupczynski, Thierry Naas   +7 more
doaj   +1 more source

Public expenditure and deficit in Spain (1958-2014) [PDF]

, 2016
La formulación de dos ecuaciones diferentes confirma la influencia del déficit en el crecimiento del gasto público en el período 1958-2014. El trabajo aporta dos novedades al análisis de los determinantes del gasto público en España: por una parte, se ...
Jaén-García, Manuel
core   +1 more source

Chromosomal Evolution in the Phylogenetic Context: A Remarkable Karyotype Reorganization in Neotropical Parrot Myiopsitta monachus (Psittacidae)

Frontiers in Genetics, 2020
Myiopsitta monachus is a small Neotropical parrot (Psittaciformes: Arini Tribe) from subtropical and temperate regions of South America. It has a diploid chromosome number 2n = 48, different from other members of the Arini Tribe that have usually 70 ...
Ivanete de Oliveira Furo, Ivanete de Oliveira Furo, Ivanete de Oliveira Furo, Rafael Kretschmer, Rafael Kretschmer, Patricia Caroline O’Brien, Jorge C. Pereira, Analía del Valle Garnero, Ricardo José Gunski, Rebecca E. O’Connor, Darren Karl Griffin, Anderson José Baia Gomes, Malcolm Andrew Ferguson-Smith, Edivaldo Herculano Correa de Oliveira, Edivaldo Herculano Correa de Oliveira, Edivaldo Herculano Correa de Oliveira   +15 more
doaj   +1 more source

Whole-Genome Sequencing and Concordance Between Antimicrobial Susceptibility Genotypes and Phenotypes of Bacterial Isolates Associated with Bovine Respiratory Disease. [PDF]

, 2017
Extended laboratory culture and antimicrobial susceptibility testing timelines hinder rapid species identification and susceptibility profiling of bacterial pathogens associated with bovine respiratory disease, the most prevalent cause of cattle ...
Abdo, Zaid, Aly, Sharif S, Belk, Keith, Blanchard, Patricia C, Davis, Jessica H, Lehenbauer, Terry W, Miller, Michael R, Morley, Paul, Noyes, Noelle, O'Rourke, Sean M, Owen, Joseph R, Prince, Daniel J, Van Eenennaam, Alison L, Young, Amy E   +13 more
core   +2 more sources

novoBreak: local assembly for breakpoint detection in cancer genomes. [PDF]

, 2017
We present novoBreak, a genome-wide local assembly algorithm that discovers somatic and germline structural variation breakpoints in whole-genome sequencing data.
Boutros, Paul, Chen, Junjie, Chen, Ken, Chen, Tenghui, Chong, Zechen, Ding, Li, Fan, Xian, Gao, Min, Lee, Anna Y, Ruan, Jue, Zhou, Wanding   +10 more
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source