Results 101 to 110 of about 50,006 (352)

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Invasive Cancer Confined to the Nipple of the Conserved Breast: A Case Report

Case Reports in Oncology, 2020
Invasive breast cancer deriving from the milk duct and lobule that develops in the nipple is extremely rare, except in Paget’s disease and skin cancer.
Miyuki Kitahara, Yasuo Hozumi, Naoto Takeuchi, Satoko Ichinohe, Mitsuki Machinaga, Tatsuo Iijima   +5 more
doaj   +1 more source

Oncoplastic breast conserving surgery.

Gland surgery, 2014
Oncoplastic breast conserving surgery is a fundamental component of the repertoire for the management of breast cancer. It facilitates removal of large volumes of breast tissue, and can improve cosmetic outcomes and patient satisfaction whilst maintaining good oncological principles, reducing re-excision and mastectomy rates and assisting in adjuvant ...
Mansfield, Lucy, Agrawal, Avi, Cutress, Ramsey I.   +2 more
openaire   +2 more sources

MC1635: Randomized Phase III Trial of Hypofractionated Radiotherapy to the Whole Breast After Breast Conserving Surgery [PDF]

, 2021
C.S. Thorpe, T.A. DeWees, Kimberly S. Corbin, L.A. McGee, Robert W. Mutter, Laura A. Vallow, Dean A. Shumway, T.Z. Vern-Gross, Michele Y. Halyard, Sameer R. Keole, S.S. Park, William W. Wong, Barbara A. Pockaj, Sarah A. McLaughlin, Michael A. Golafshar, Gabriella F. Bulman, Carlos Vargas   +16 more
openalex   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Comparison of quality of life, satisfaction with surgery and shoulder-arm morbidity in breast cancer survivors submitted to breast-conserving therapy or mastectomy followed by immediate breast reconstruction

Clinics, 2010
OBJECTIVES: This study was designed to compare the prevalence of shoulder-arm morbidity, patient satisfaction with surgery and the quality of life of women submitted to breast-conserving therapy or modified radical mastectomy and immediate breast ...
Renata Freitas-Silva, Délio Marques Conde, Ruffo de Freitas-Júnior, Edson Zangiacomi Martinez   +3 more
doaj   +1 more source

Rapid Arbitrary‐Shape Microscopy of Unsectioned Tissues for Precise Intraoperative Tumor Margin Assessment

Advanced Science, EarlyView.
This study presents a novel microscopic imaging system capable of rapid, section‐free scanning of irregular tissue surfaces, delivering high sensitivity for detecting cancer cell clusters during intraoperative tumor margin assessment. Abstract Rapid and accurate intraoperative examination of tumor margins is crucial for precise surgical treatment, yet ...
Zhicheng Shao, Xiangwei Meng, Peifen Fu, Keer Huang, Xibei Chen, Yue Ying, Jun Li, Yuxin Zheng, Xiaolong Li, Hyeon Jeong Lee, Jingyi Feng, Yuexin Lu, Runping Cai, Xiongling Jiang, Qing Chen, Hong Zhang, Xiaoyong Man, Li Lin   +17 more
wiley   +1 more source

Ethnicity and the surgical management of early invasive breast cancer in over 164 000 women

BJS (British Journal of Surgery), EarlyView., 2020
This large national study examined in detail the patterns in surgical management of early breast cancer in women of different ethnicities. Allowing for different patterns of age and stage at presentation, the surgical management of early breast cancer was similar in all women, regardless of ethnicity. All treated the same Background Limited information
T. Gathani, K. Chiuri, J. Broggio, G. Reeves, I. Barnes   +4 more
wiley   +1 more source

Breast cancer in Malta : a comparative study between the year 2000 and 2010 [PDF]

, 2013
Introduction: During the last decade, Malta experienced the introduction of a number of programmes and initiatives aiming to raise risk and cancer awareness on breast cancer.
Caruana Dingli, Gordon, Caruana, Mandy
core  

Potential benefits of crawl position for prone radiation therapy in breast cancer [PDF]

, 2017
Purpose: To investigate crawl position with the arm at the treated side alongside the body and at the opposite side above the head for prone treatment in patients requiring breast and regional lymph node irradiation. Methods: Patient support devices for
Boute, Bert, De Gersem, Werner, De Neve, Wilfried, Detand, Jan, Monten, Christel, Paelinck, Leen, Speleers, Bruno, Van de Velde, Joris, Van Greveling, Annick, Van Hoof, Tom, Veldeman, Liv, Vercauteren, Tom   +11 more
core   +1 more source