Results 1 to 10 of about 2,528,262 (264)

A Novel Necroptosis-Associated lncRNA Signature Can Impact the Immune Status and Predict the Outcome of Breast Cancer

Journal of Immunology Research, 2022
Breast cancer (BRCA) is one of the leading causes of death among women worldwide, and drug resistance often leads to a poor prognosis. Necroptosis is a type of programmed cell death (PCD) and exhibits regulatory effects on tumor progression, but few ...
Xin Zhang, Xingda Zhang, Guozheng Li, Yi Hao, Lei Liu, Lei Zhang, Yihai Chen, Jiale Wu, Xinheng Wang, Shuai Yang, Shouping Xu   +10 more
doaj   +1 more source

Endoscopic Nipple- or Skin-Sparing Mastectomy and Immediate Breast Reconstruction with Endoscopic Harvesting of the Latissimus Dorsi Flap: A Preliminary Experience of an Innovative Technique

The Breast Journal, 2022
Background. Endoscopic nipple- or skin-sparing mastectomy (E-N/SSM) and endoscopic latissimus dorsi muscle flap (E-LDMF) harvest have been operational difficulties over decades.
Yu Feng, Nan Wen, Faqing Liang, Jiao Zhou, Xiangquan Qin, Xinran Liu, Juan Li, Mengxue Qiu, Huanzuo Yang, Zhenggui Du   +9 more
doaj   +1 more source

Identification of Crucial lncRNAs for Luminal A Breast Cancer through RNA Sequencing

International Journal of Endocrinology, 2022
Background. The growing body of evidence indicates aberrant expression of long noncoding RNAs (lncRNAs) in breast cancer. Nevertheless, a few studies have focused on identifying key lncRNAs for patients with luminal A breast cancer.
Xinjian Jia, Hai Lei, Xuemei Jiang, Ying Yi, Xue Luo, Junyan Li, Yu Chen, Sha Liu, Chengcheng Yang   +8 more
doaj   +1 more source

High-Throughput Screening and Molecular Dynamics Simulation of Natural Products for the Identification of Anticancer Agents against MCM7 Protein

Applied Bionics and Biomechanics, 2022
Minichromosome maintenance complex component 7 (MCM7) belongs to the minichromosome maintenance family that is necessary for the initiation of eukaryotic DNA replication.
Xin Zhang, Hui Chen, Hui Lin, Ronglan Wen, Fan Yang   +4 more
doaj   +1 more source

Changes in Breast Cancer Presentation during COVID-19: Experience in an Urban Academic Center

International Journal of Breast Cancer, 2023
The COVID-19 pandemic strained healthcare systems worldwide, delaying breast cancer screening and surgery. In 2019, approximately 80% of breast cancers in the U.S.
Brian Diskin, Nakisa Pourkey, Freya Schnabel, Pabel Miah, Charles DiMaggio, Deborah Axelrod, Richard Shapiro, Amber A. Guth   +7 more
doaj   +1 more source

Development and Validation of a Novel PPAR Signaling Pathway-Related Predictive Model to Predict Prognosis in Breast Cancer

Journal of Immunology Research, 2022
This study is aimed at exploring the potential mechanism of the PPAR signaling pathway in breast cancer (BRCA) and constructing a novel prognostic-related risk model.
Yingkun Xu, Dan Shu, Meiying Shen, Qiulin Wu, Yang Peng, Li Liu, Zhenrong Tang, Shun Gao, Yuan Wang, Shengchun Liu   +9 more
doaj   +1 more source

CASP9 As a Prognostic Biomarker and Promising Drug Target Plays a Pivotal Role in Inflammatory Breast Cancer

International Journal of Analytical Chemistry, 2022
Background. Inflammatory breast cancer (IBC) is one of the most rare and aggressive subtypes of primary breast cancer (BC). Our study aimed to explore hub genes related to the pathogenesis of IBC, which could be considered as novel molecular biomarkers ...
Mingdi Zhang, Kejin Wu, Maoli Wang, Fang Bai, Hongliang Chen   +4 more
doaj   +1 more source

MAPK/ERK-CBP-RFPL-3 Mediates Adipose-Derived Stem Cell-Induced Tumor Growth in Breast Cancer Cells by Activating Telomerase Reverse Transcriptase Expression

Stem Cells International, 2022
Adipose-derived stem cells (ASCs) improve the self-renewal and survival of fat grafts in breast reconstruction after oncology surgery. However, ASCs have also been found to enhance breast cancer growth, and its role in tumor proliferation remains largely
Wenjie Li, Cheng Qian, Fei Ma, Meng Liu, Xiaojun Sun, Xu Liu, Chunxiao Liu, Zhenghua Chen, Weichang Ma, Jian Liu, Haiqian Xu, Zhenlin Yang   +11 more
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“An Unusual Pattern of Metastasis” Metastatic Malignant Thymoma Presented with Breast Lump: A Case Report and Literature Review

Case Reports in Surgery, 2023
Metastatic lesions to the breast from extramammary malignant neoplasms are rare and reported account for 0.5–6.6% of all breast malignancies. Distant metastasis of thymoma is even rarer, especially to extrathoracic regions.
Kah-Seng Khoo, Kavinya Diana T. Nadesalingam, Diana Bee-Lan Ong, Li-Ying Teoh, Mei-Sze Teh, Suniza Jamaris, Mee-Hoong See   +6 more
doaj   +1 more source

Comparative Efficacy of Neoadjuvant Endocrine Therapy, Neoadjuvant Chemotherapy, and Neoadjuvant Chemo-Endocrine Therapy in Estrogen Receptor–Positive Breast Cancer Patients: A Meta-Analysis

The Breast Journal
Neoadjuvant therapy before surgery offers varying benefits as a well-established treatment option for breast cancer. This study specifically evaluated the effectiveness of neoadjuvant endocrine therapy (NET), neoadjuvant chemotherapy (NCT), and ...
Yi Yuan, Ning Cui, Ziyi Xu, Chang Cui, Zongpeng Zhou, Zhefu Ma   +5 more
doaj   +1 more source