Results 1 to 10 of about 131,135 (260)

Modification of PLAC8 by UFM1 affects tumorous proliferation and immune response by impacting PD-L1 levels in triple-negative breast cancer

Journal for ImmunoTherapy of Cancer, 2022
Background Triple-negative breast cancer is characterized by a poor prognosis and lack of targeted treatments, and thus, new targeting markers and therapeutic strategies are urgently needed.
Cong Chen, Linbo Wang, Xun Zhang, Ling Xu, Misha Mao, Yongxia Chen, Jingjing Yang, Yifan Cheng, Feiyang Ji, Jichun Zhou, Zhaoqing Li, Siwei Ju, Jiahang Zhang   +12 more
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Clinical Implications of iNOS Levels in Triple-Negative Breast Cancer Responding to Neoadjuvant Chemotherapy. [PDF]

PLoS ONE, 2015
Triple-negative breast cancer is a high-risk breast cancer with poor survival rate. To date, there is a lack of targeted therapy for this type of cancer. One unique phenomenon is that inflammatory breast cancer is frequently triple negative.
Zining Jin, Wenqian Wang, Nan Jiang, Lei Zhang, Yiming Li, Xiaoyin Xu, Shouliang Cai, Liang Wei, Xuhong Liu, Guanglei Chen, Yizhen Zhou, Cheng Liu, Zhan Li, Feng Jin, Bo Chen   +14 more
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Metabolic Reprogramming in Triple-Negative Breast Cancer

Frontiers in Oncology, 2020
Metabolic reprogramming is an emerging hallmark of cancer cells, in which cancer cells exhibit distinct metabolic phenotypes to fuel their proliferation and progression.
Xiangyu Sun, Mozhi Wang, Mengshen Wang, Xueting Yu, Jingyi Guo, Tie Sun, Xinyan Li, Litong Yao, Haoran Dong, Yingying Xu   +9 more
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HJURP regulates cell proliferation and chemo-resistance via YAP1/NDRG1 transcriptional axis in triple-negative breast cancer

Cell Death and Disease, 2022
Triple-negative breast cancer is still a difficult point in clinical treatment at present, and a deep study of its pathogenesis has great clinical value. Therefore, our research mainly focuses on exploring the progression of triple-negative breast cancer
Misha Mao, Yunlu Jia, Yongxia Chen, Jingjing Yang, Ling Xu, Xun Zhang, Jichun Zhou, Zhaoqing Li, Cong Chen, Siwei Ju, Linbo Wang   +10 more
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Molecular characteristics and metastasis predictor genes of triple-negative breast cancer: a clinical study of triple-negative breast carcinomas. [PDF]

PLoS ONE, 2012
BackgroundTriple-negative breast cancer is a subtype of breast cancer with aggressive tumor behavior and distinct disease etiology. Due to the lack of an effective targeted medicine, treatment options for triple-negative breast cancer are few and ...
Wen-Hung Kuo, Yao-Yin Chang, Liang-Chuan Lai, Mong-Hsun Tsai, Chuhsing Kate Hsiao, King-Jen Chang, Eric Y Chuang   +6 more
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Immune Effect of Active Components of Traditional Chinese Medicine on Triple-Negative Breast Cancer

Frontiers in Pharmacology, 2021
Triple-negative breast cancers are heterogeneous, poorly prognostic, and metastatic malignancies that result in a high risk of death for patients. Targeted therapy for triple-negative breast cancer has been extremely challenging due to the lack of ...
Wenjie Zhao, Wenjie Zhao, Jinhua Liu, Yaqun Li, Zichao Chen, Zichao Chen, Dongmei Qi, Dongmei Qi, Zhen Zhang   +8 more
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MiR-133 Targets YES1 and Inhibits the Growth of Triple-Negative Breast Cancer Cells

Technology in Cancer Research & Treatment, 2020
Triple-negative breast cancer shows worse outcome compared with other subtypes of breast cancer. The discovery of dysregulated microRNAs and their roles in the progression of triple-negative breast cancer provide novel strategies for the treatment of ...
Guochen Zhang MD, Junlan Wang BS, Ruilin Zheng MD, Beibei Song BS, Li Huang PhD, Yujiang Liu MD, Yating Hao MD, Xiangdong Bai PhD   +7 more
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Assessment of outcomes and novel immune biomarkers in metaplastic breast cancer: a single institution retrospective study

World Journal of Surgical Oncology, 2020
Background Metaplastic breast cancer remains poorly characterized given its rarity and heterogeneity. The majority of metaplastic breast cancers demonstrate a phenotype of triple-negative breast cancer; however, differences in clinical outcomes between ...
Evan Morgan, Anupama Suresh, Akaansha Ganju, Daniel G. Stover, Robert Wesolowski, Sagar Sardesai, Anne Noonan, Raquel Reinbolt, Jeffrey VanDeusen, Nicole Williams, Mathew A. Cherian, Zaibo Li, Gregory Young, Marilly Palettas, Julie Stephens, Joseph Liu, Amanda Luff, Bhuvaneswari Ramaswamy, Maryam Lustberg   +18 more
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miR-331-3p Suppresses Cell Proliferation in TNBC Cells by Downregulating NRP2

Technology in Cancer Research & Treatment, 2020
Purpose: Triple-negative breast cancer is characterized by fast progression with high possible for metastasis and poor survival. Dysfunction of microRNAs plays an important role in the initiation and progression of cancer.
Mingchuan Zhao PhD, Mengmeng Zhang PhD, Zhonghua Tao PhD, Jun Cao PhD, Leiping Wang PhD, Xichun Hu PhD, MD   +5 more
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Avoidance and Period-Shortening of Neoadjuvant Chemotherapy Against Triple-Negative Breast Cancer in Stages I and II: Importance of Ki-67 Labeling Index and the Recognition of Apocrine-Type Lesions

Technology in Cancer Research & Treatment, 2020
Background: Triple-negative breast cancer encompasses heterogeneous subtypes. Neoadjuvant chemotherapy is ineffective against some triple-negative breast cancers, while others show a favorable prognosis despite chemoresistance.
Koichi Kubouchi MD, Kyosuke Shimada MD, Takamichi Yokoe MD, Yutaka Tsutsumi MD   +3 more
doaj   +1 more source