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Male Triple-Negative Breast Cancer [PDF]

open access: yesCureus, 2021
Male breast cancer is a rarely encountered disease, when compared with female breast cancer, often detected in more advanced stage at the time of diagnosis, and associated with more lymph node metastasis rates, more estrogen receptors positivity, and less human epidermal growth factor receptor-2 expression (HER-2) rates.
Qavi, Qasif   +4 more
openaire   +2 more sources

Spatial predictors of immunotherapy response in triple-negative breast cancer

open access: yesNature, 2023
Immune checkpoint blockade (ICB) benefits some patients with triple-negative breast cancer, but what distinguishes responders from non-responders is unclear^ 1 .
Xiao Qian Wang   +26 more
semanticscholar   +1 more source

Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence. [PDF]

open access: yes, 2016
We have previously developed a genetically-engineered GFP-expressing telomerase-dependent adenovirus, OBP-401, which can selectively illuminate cancer cells.
Bouvet, Michael   +9 more
core   +2 more sources

Therapies for triple negative breast cancer [PDF]

open access: yesExpert Opinion on Pharmacotherapy, 2015
Triple negative breast cancer (TNBC) is a heterogeneous disease associated with a high risk of recurrence, and therapeutic options are currently limited to cytotoxic therapy. Germ-line mutations may occur in up to 20% of unselected patients with TNBC, which may serve as a biomarker identifying which patients may have tumors that are particularly ...
Eleni, Andreopoulou   +3 more
openaire   +2 more sources

A Machine Learning Approach to Differentiate Two Specific Breast Cancer Subtypes Using Androgen Receptor Pathway Genes

open access: yesTechnology in Cancer Research & Treatment, 2021
Triple-negative breast cancer is a heterogeneous disease with different molecular and histological subtypes. The Androgen receptor is expressed in a portion of triple-negative breast cancer cases and the activation of the androgen receptor pathway is ...
Taobo Hu   +3 more
doaj   +1 more source

Phospho-Akt expression is high in a subset of triple negative breast cancer patients [PDF]

open access: yes, 2014
The most commonly used biomarkers to predict the response of breast cancer patients to therapy are oestrogen receptor (ER), progesterone receptor (PgR), and human epidermal growth factor receptor 2 (HER2).
Baldacchino, Shawn   +6 more
core   +1 more source

Triple negative breast cancer: Pitfalls and progress

open access: yesnpj Breast Cancer, 2022
Triple negative breast cancer (TNBC) is characterized by the lack of estrogen and progesterone receptor expression and lacks HER2 overexpression or gene amplification.
P. Zagami, L. Carey
semanticscholar   +1 more source

Family history of breast and ovarian cancer and triple negative subtype in hispanic/latina women. [PDF]

open access: yes, 2014
Familial breast and ovarian cancer prevalence was assessed among 1150 women of Mexican descent enrolled in a case-only, binational breast cancer study. Logistic regression was conducted to compare odds of triple negative breast cancer (TNBC) to non-TNBC ...
Anderson, Kristin   +13 more
core   +2 more sources

Triple Negative Breast Cancer Treatment Options and Limitations: Future Outlook

open access: yesPharmaceutics, 2023
Triple negative breast cancer (TNBC) has a negative expression of estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptors (HER2).
O. Obidiro, G. Battogtokh, E. Akala
semanticscholar   +1 more source

Medullary breast cancer is a predominantly triple-negative breast cancer – histopathological analysis and comparison with invasive ductal breast cancer

open access: yesArchives of Medical Science, 2019
Introduction Medullary breast cancer (MdBC) is an uncommon type of breast cancer representing 1–7% of all cases. It is characterized by the occurrence of many histopathological features associated with a high grade of malignancy.
Michał P. Budzik   +6 more
doaj   +1 more source

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