Results 51 to 60 of about 406,491 (336)

FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control

Frontiers in Oncology, 2019
Background: Triple negative breast cancers are aggressive, enriched with cancer stem cells, and lack effective targeted therapies with little side effects.Methods: We isolated cancer stem cells from two triple negative breast cancer cell lines via cell ...
Xiaofeng Dai, Shuo Zhang, Hongye Cheng, Dongyan Cai, Dongyan Cai, Xiao Chen, Zhaohui Huang, Zhaohui Huang   +7 more
doaj   +1 more source

Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages [PDF]

, 2018
Background: As crucial regulators of the immune response against pathogens, macrophages have been extensively shown also to be important players in several diseases, including cancer. Specifically, breast cancer macrophages tightly control the angiogenic
Blandino, Giovanni, Donzelli, Sara, Fazi, Francesco, Fontemaggi, Giulia, Gallo, Enzo, Iosue, Ilaria, Masciarelli, Silvia, Melucci, Elisa, Milano, Elisa, Mottolese, Marcella, Pruszko, Magdalena, Sacconi, Andrea, Terrenato, Irene, Zylicz, Alicja, Zylicz, Maciej   +14 more
core   +3 more sources

Radiological diagnostics of triple negative breast cancer: a review

Acta Medica Lituanica, 2011
Background. Triple negative breast cancer has a poor prognosis. Therefore, it is vital to detect this subtype of breast cancer in its early stage. The imaging features of this clinically important subtype of breast cancer are not well known.
Sigutė STADALNYKAITĖ, Rūta BRIEDIENĖ
doaj   +1 more source

Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer [PDF]

, 2016
Adenoid cystic carcinoma of the breast is a rare histologic type of triple-negative breast cancer with an indolent clinical behavior, often driven by the MYB-NFIB fusion gene.
Badve, Sunil S., Bamba, Masamichi, Burke, Kathleen A., De Filippo, Maria R., Ellis, Ian O., Fuhrmann, Laetitia, Fusco, Nicola, Geyer, Felipe C., Guerini-Rocco, Elena, Ichihara, Shu, Jungbluth, Achim A., Lim, Raymond S., Martelotto, Luciano G., Moritani, Suzuko, Ng, Charlotte K.Y., Piscuoglio, Salvatore, Reis-Filho, Jorge S., Schultheis, Anne M., Vincent-Salomon, Anne, Wang, Lu, Weigelt, Britta   +20 more
core   +2 more sources

The Omics of Triple-Negative Breast Cancers [PDF]

Clinical Chemistry, 2014
Abstract BACKGROUND Triple-negative breast cancers (TNBC) do not represent a single disease subgroup and are often aggressive breast cancers with poor prognoses. Unlike estrogen/progesterone receptor and HER2 (human epidermal growth factor receptor 2) breast cancers, which are responsive to targeted ...
Hong, Xu, Peter, Eirew, Sarah C, Mullaly, Samuel, Aparicio   +3 more
openaire   +2 more sources

Modulation of the BRCA1 Protein and Induction of Apoptosis in Triple Negative Breast Cancer Cell Lines by the Polyphenolic Compound Curcumin

Breast Cancer: Basic and Clinical Research, 2009
In the current study, we sought to examine the effects of curcumin in a specific type of breast cancer called triple negative breast cancer. These cancers lack expression of the estrogen and progesterone receptors and do not over-express HER2.
Danica L. Rowe, Tuba Ozbay, Ruth M. O’Regan, Rita Nahta   +3 more
doaj   +2 more sources

Triple negative breast cancer: new perspectives for targeted therapies [PDF]

, 2015
Breast cancer is a heterogeneous disease, encompassing a large number of entities showing different morphological features and having clinical behaviors.
Caruso, Davide, Frati, Luigi, Minozzi, Marina, Papa, Anselmo, Rossi, Luigi, Tomao, Federica, Tomao, Silverio, Vici, Patrizia, Zaccarelli, Eleonora   +8 more
core   +1 more source

A Review of Triple-Negative Breast Cancer

Cancer Control, 2010
Background An estimated 1 million cases of breast cancer are diagnosed annually worldwide. Of these, more than 170,000 are described as triple-negative. Triple-negative breast cancer (TNBC) is defined by the lack of protein expression of estrogen receptor (ER) and progesterone receptor (PR) and the absence of HER2 protein overexpression.
Roohi, Ismail-Khan, Marilyn M, Bui
openaire   +2 more sources

Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection

PLoS ONE, 2016
Triple-negative breast cancer (TNBC) is a heterogeneous disease that can be classified into distinct molecular subtypes by gene expression profiling.
B. Lehmann, B. Jovanovic, Xi Chen, M. V. Estrada, Kimberly N. Johnson, Y. Shyr, H. Moses, M. Sanders, J. Pietenpol   +8 more
semanticscholar   +1 more source

Recent advances in targeted strategies for triple-negative breast cancer

Journal of Hematology & Oncology, 2023
Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer, negatively expresses estrogen receptor, progesterone receptor, and the human epidermal growth factor receptor 2 (HER2).
Shuangli Zhu, Yuze Wu, Bin Song, Ming Yi, Yuheng Yan, Qingtao Mei, Kongming Wu   +6 more
semanticscholar   +1 more source