Results 61 to 70 of about 406,491 (336)

Qualitative exploration of patients’ experiences with Intrabeam TARGeted Intraoperative radioTherapy (TARGIT-IORT) and External-Beam RadioTherapy Treatment (EBRT) for breast cancer

BMJ Open
Objective To gather a deep qualitative understanding of the perceived benefits and impacts of External-Beam RadioTherapy (EBRT) and TARGeted Intraoperative radioTherapy (TARGIT-IORT) using Intrabeam to assess how the treatments affected patient/care ...
Jayant S Vaidya, Siobhan Laws, Jennifer Royle, Sandeep Kumar Bagga, Natalie Swiderska, Charlotte Hooker, Marie Ennis-O'Connor, Siobhan Freeney, Dympna Watson, Robin Woolcock, George Lodge   +10 more
doaj   +1 more source

HDAC inhibition potentiates immunotherapy in triple negative breast cancer. [PDF]

, 2017
Triple-negative breast cancer (TNBC) represents a more aggressive and difficult subtype of breast cancer where responses to chemotherapy occur, but toxicity is significant and resistance often follows. Immunotherapy has shown promising results in various
Ali, Niwa, Budillon, Alfredo, Krings, Gregor, Munster, Pamela N, Park, Jeenah, Pawlowska, Nela, Rosenblum, Michael D, Terranova-Barberio, Manuela, Thomas, Scott   +8 more
core   +1 more source

The addition of bevacizumab to standard chemotherapy in breast cancer : which patient benefits the most? [PDF]

, 2013
Bevacizumab, a humanized monoclonal antibody directed against vascular endothelial growth factor, is an effective and well-tolerated treatment option for patients with breast cancer.
Cocquyt, Veronique, Denys, Hannelore, KRUSE, VIBEKE, Van Belle, Simon, Van den Broecke, Rudy   +4 more
core   +2 more sources

Leveraging diverse cell-death patterns to predict the prognosis and drug sensitivity of triple-negative breast cancer patients after surgery.

International Journal of Surgery, 2022
BACKGROUND Postoperative progression and chemotherapy resistance is the major cause of treatment failure in patients with triple-negative breast cancer (TNBC).
Yutian Zou, Jindong Xie, Shaoquan Zheng, Wen-qing Liu, Yuhui Tang, Wenwen Tian, X. Deng, Linyu Wu, Yue Zhang, Chau-Wei Wong, Duxun Tan, Qing Liu, Xiaoming Xie   +12 more
semanticscholar   +1 more source

Dual PI3K and Wnt pathway inhibition is a synergistic combination against triple negative breast cancer [PDF]

, 2017
Triple negative breast cancer accounts for 15-20% of all breast cancer cases, but despite its lower incidence, contributes to a disproportionately higher rate of mortality.
Atale, Rutuja V., Hancock, Bradley A., Jones, David R., Pollok, Karen E., Radovich, Milan, Sinn, Anthony L., Solzak, Jeffrey P.   +6 more
core   +1 more source

Triple-Negative Breast Cancer: A Brief Review About Epidemiology, Risk Factors, Signaling Pathways, Treatment and Role of Artificial Intelligence

Frontiers in Molecular Biosciences, 2022
Triple-negative breast cancer (TNBC) is a kind of breast cancer that lacks estrogen, progesterone, and human epidermal growth factor receptor 2. This cancer is responsible for more than 15–20% of all breast cancers and is of particular research interest ...
N. Almansour
semanticscholar   +1 more source

Locally Advanced Spiroadenocarcinoma in the Regional Axilla of a Breast Cancer Patient: Hallmarks of Definitive Diagnosis and Management. [PDF]

, 2015
Eccrine spiroadenocarcinoma is an extremely rare malignant eccrine gland tumor which may masquerade as other more common malignancies such as poorly differentiated squamous carcinoma or metastatic breast cancer.
Canter, Robert J, Fung, Maxwell A, Gingrich, Alicia A, Konia, Thomas   +3 more
core   +2 more sources

Prevalence of BRCA1 and BRCA2 gene mutations in Chinese patients with high‐risk breast cancer

Molecular Genetics & Genomic Medicine, 2019
Background Breast cancer is the most common cancer among women worldwide. Here, we report the prevalence of BRCA1/2 mutations in patients with high‐risk breast cancer from Inner Mongolia and Jilin, China, which was a part of a nationwide project on the ...
Xiaozhen Wang, Haimeng Liu, Amina Maimaitiaili, Gang Zhao, Sijie Li, Zheng Lv, Di Wu, Aiping Shi, Xin Guan, Hongyao Jia, Menghan Li, Dong Song, Lihua Kang, Bing Han, Tong Fu, Ming Yang, Zhu Zhu, Ye Du, Yanqiu Song, Jinghui Hong, Zhimin Fan   +20 more
doaj   +1 more source

Identification of prognostic genes for recurrent risk prediction in triple negative breast cancer patients in Taiwan.

PLoS ONE, 2011
Discrepancies in the prognosis of triple negative breast cancer exist between Caucasian and Asian populations. Yet, the gene signature of triple negative breast cancer specifically for Asians has not become available. Therefore, the purpose of this study
Lee H Chen, Wen-Hung Kuo, Mong-Hsun Tsai, Pei-Chun Chen, Chuhsing K Hsiao, Eric Y Chuang, Li-Yun Chang, Fon-Jou Hsieh, Liang-Chuan Lai, King-Jen Chang   +9 more
doaj   +1 more source

Targeting KK-LC-1 inhibits malignant biological behaviors of triple-negative breast cancer

Journal of Translational Medicine, 2023
Background Cancer/testis antigens (CTAs) participate in the regulation of malignant biological behaviors in breast cancer. However, the function and mechanism of KK-LC-1, a member of the CTA family, in breast cancer are still unclear.
Xudong Zhu, Jiawen Bu, Tong zhu, Yi Jiang   +3 more
doaj   +1 more source