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Progress of Immunotherapy and Its Application in Triple Negative Breast Cancer
Zhongliu Fangzhi Yanjiu, 2020 In recent years, potential new therapeutic options have been yielded for the immunotherapy of invasive cancers. The most important breakthrough in breast cancer research today is to understand the immune features and profiles of triple negative breast ...
ZHENG Hongmei +6 more
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Technology in Cancer Research & Treatment, 2023 Breast cancer is the most common malignancy and the second most common cause of cancer-related mortality in women. Triple-negative breast cancers do not express estrogen receptors, progesterone receptors, or human epidermal growth factor receptor 2 and ...
Boya Lu MD +3 more
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Frontiers in Oncology, 2023 Triple-negative breast cancer refers to breast cancer patients with negative estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor (HER2).
Ruoyan Qin +6 more
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Triple Negative Breast Cancer – An Overview [PDF]
Hereditary Genetics, 2012 Triple Negative Breast Cancer (TNBC) is a heterogeneous disease that based on immunohistochemistry (IHC) is estrogen receptor (ER) negative, progesterone receptor (PR) negative and human epidermal growth factor receptor 2 (HER2) negative. TNBC is typically observed in young AA women and Hispanic women who carry a mutation in the BRCA1 gene.
Aysola, Kartik +12 more
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Advances in immunotherapy for triple-negative breast cancer
Molecular Cancer, 2023 Background Immunotherapy has recently emerged as a treatment strategy which stimulates the human immune system to kill tumor cells. Tumor immunotherapy is based on immune editing, which enhances the antigenicity of tumor cells and increases the ...
Yang Liu +8 more
semanticscholar +1 more source
Management of triple negative breast cancer
The Breast, 2010 Triple negative breast cancer (TNBC) accounts for approximately 15% of breast cancer cases. TNBC is an immunohistochemically defined subtype, with significant diversity within the subtype. Generally TNBC occurs in younger women and is marked by high rates of relapse, visceral and CNS metastases, and early death.
C. Oakman, G. Viale, A. Di Leo
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Cell Metabolism, 2022 Treatment of triple-negative breast cancer (TNBC) remains challenging. Deciphering the orchestration of metabolic pathways in regulating ferroptosis will provide new insights into TNBC therapeutic strategies.
Fan Yang +10 more
semanticscholar +1 more source
Cell Metabolism, 2022 Immunotherapy has achieved limited success in patients with triple-negative breast cancer (TNBC), an aggressive disease with a poor prognosis. Commensal microbiota have been proven to colonize the mammary gland, but whether and how they modulate the ...
Hai Wang +19 more
semanticscholar +1 more source
A molecular approach to triple-negative breast cancer: targeting the Notch signaling pathway [PDF]
Einstein (São Paulo)Introduction Triple-negative breast cancer is an aggressive subtype of breast cancer characterized by the absence of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 expression. This phenotype renders triple-negative
Isabele Pardo +3 more
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Discover Oncology, 2023 Purpose Triple-negative breast cancer continues to be one of the leading causes of death in women, making up 7% of all cancer deaths. Tumor-treating electric fields are low-energy, low-frequency oscillating electric fields that induce an anti ...
Austin R. Smothers +6 more
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