Results 41 to 50 of about 6,967,236 (252)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Identification of new markers for the characterization and isolation of breast cancer stem cells [PDF]

, 2013
Breast cancer is the first human carcinoma for which a putative cancer stem cell subpopulation (BCSC) has been isolated with the CD44+/CD24-/low phenotype.
Leccia, Felicia
core   +1 more source

Identification and prognostic value of anterior gradient protein 2 expression in breast cancer based on tissue microarray

Tumor Biology, 2017
Breast cancer has attracted substantial attention as one of the major cancers causing death in women. It is crucial to find potential biomarkers of prognostic value in breast cancer. In this study, the expression pattern of anterior gradient protein 2 in
Jilong Guo, Guohua Gong, Bin Zhang
doaj   +1 more source

Targeting KK-LC-1 inhibits malignant biological behaviors of triple-negative breast cancer

Journal of Translational Medicine, 2023
Background Cancer/testis antigens (CTAs) participate in the regulation of malignant biological behaviors in breast cancer. However, the function and mechanism of KK-LC-1, a member of the CTA family, in breast cancer are still unclear.
Xudong Zhu, Jiawen Bu, Tong zhu, Yi Jiang   +3 more
doaj   +1 more source

Association of Parity with Triple Negative Breast Cancer, A Case Control Study

Pakistan Armed Forces Medical Journal, 2023
Objective: To find out association between number of children and triple negative breast cancer among females presenting at a tertiary care hospital of Karachi. Study Design: Case control study.
Batool Aslam Memon, Ghulam Haider, Mahnoor Ahsan, Khalil Ahmed, Asra Taj, Berkha Rani   +5 more
doaj   +1 more source

A novel prognostic two-gene signature for triple negative breast cancer [PDF]

, 2020
The absence of a robust risk stratification tool for triple negative breast cancer (TNBC) underlies imprecise and non-selective treatment of these patients with cytotoxic chemotherapy.
Alsaleem, MA, Elemento, O, Toss, MS, Joseph, C, Rakha, Emad, Alsaleem, Mansour A, Raafat, S, Mongan, NP, Ball, G, Ellis, Ian O, Davis, Melissa, Elemento, Olivier, Bhattarai, S, Green, Andrew, Ball, Graham, Aleskandarany, Mohammed, Rida, PCG, Rida, Padmashree C G, Ogden, A, Joseph, Chitra, Green, A, Bhattarai, Shristi, Rakha, E, Toss, Michael S, Aneja, Ritu, Ogden, Angela, Ellis, IO, Aleskandarany, M, Mongan, Nigel P., Davis, M, Raafat, Sara, Khani, F, Aneja, R, Khani, Francesca   +33 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Methylseleninic acid enhances paclitaxel efficacy for the treatment of triple-negative breast cancer. [PDF]

PLoS ONE, 2012
A major challenge in breast cancer therapy is the lack of an effective therapeutic option for a particularly aggressive subtype of breast cancer, triple-negative breast cancer.
Yanfeng Qi, Xueqi Fu, Zhenggang Xiong, Haitao Zhang, Steven M Hill, Brian G Rowan, Yan Dong   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Acinic cell carcinoma of the breast: A comprehensive review

Breast, 2022
Acinic cell carcinoma of the breast is a rare special subtype of breast cancer in the category of salivary gland-type tumors. It is morphologically similar to acinic cell carcinomas of salivary glands and pancreas and has a triple-negative phenotype ...
Azra Ajkunic, Faruk Skenderi, Nada Shaker, Saghir Akhtar, Janez Lamovec, Zoran Gatalica, Semir Vranic   +6 more
doaj   +1 more source