Results 11 to 20 of about 406,491 (336)

Risk of regional recurrence in triple-negative breast cancer patients: a Dutch cohort study [PDF]

, 2016
Triple-negative breast cancer is associated with early recurrence and low survival rates. Several trials investigate the safety of a more conservative approach of axillary treatment in clinically T1-2N0 breast cancer.
Boer, Maaike de, Duijsens, Gaston H.N.M., Lobbes, Marc B.I., Roozendaal, Lori M. van, Siesling, Sabine, Smidt, Marjolein L., Smit, Leonie H.M., Vries, Bart de, Wilt, Johannes H.W. de   +8 more
core   +8 more sources

Molecular characteristics and metastasis predictor genes of triple-negative breast cancer: a clinical study of triple-negative breast carcinomas. [PDF]

PLoS ONE, 2012
BackgroundTriple-negative breast cancer is a subtype of breast cancer with aggressive tumor behavior and distinct disease etiology. Due to the lack of an effective targeted medicine, treatment options for triple-negative breast cancer are few and ...
Wen-Hung Kuo, Yao-Yin Chang, Liang-Chuan Lai, Mong-Hsun Tsai, Chuhsing Kate Hsiao, King-Jen Chang, Eric Y Chuang   +6 more
doaj   +1 more source

Triple-negative breast cancer molecular subtyping and treatment progress

Breast Cancer Research, 2020
Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor receptor 2 (HER-2), has clinical features that include high invasiveness,
Li Yin, Jiang-jie Duan, X. Bian, Shi-cang Yu   +3 more
semanticscholar   +1 more source

MiR-133 Targets YES1 and Inhibits the Growth of Triple-Negative Breast Cancer Cells

Technology in Cancer Research & Treatment, 2020
Triple-negative breast cancer shows worse outcome compared with other subtypes of breast cancer. The discovery of dysregulated microRNAs and their roles in the progression of triple-negative breast cancer provide novel strategies for the treatment of ...
Guochen Zhang MD, Junlan Wang BS, Ruilin Zheng MD, Beibei Song BS, Li Huang PhD, Yujiang Liu MD, Yating Hao MD, Xiangdong Bai PhD   +7 more
doaj   +1 more source

Immune Effect of Active Components of Traditional Chinese Medicine on Triple-Negative Breast Cancer

Frontiers in Pharmacology, 2021
Triple-negative breast cancers are heterogeneous, poorly prognostic, and metastatic malignancies that result in a high risk of death for patients. Targeted therapy for triple-negative breast cancer has been extremely challenging due to the lack of ...
Wenjie Zhao, Wenjie Zhao, Jinhua Liu, Yaqun Li, Zichao Chen, Zichao Chen, Dongmei Qi, Dongmei Qi, Zhen Zhang   +8 more
doaj   +1 more source

Theranostics for Triple-Negative Breast Cancer

Diagnostics, 2023
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with poor prognosis. Current endocrine therapy or anti HER-2 therapy is not available for these patients. Chemotherapeutic treatment response varies among patients due to the disease heterogeneity. To overcome these challenges, theranostics for treating TNBC have been widely
Hyeryeon Choi, Kwangsoon Kim
openaire   +3 more sources

Triple Negative Breast Cancer

Asian Pacific Journal of Cancer Prevention, 2014
Triple-negative breast cancers (TNBC), characterized by absence of the estrogen receptor (ER) and progesterone receptor (PR) and lack of overexpression of human epidermal growth factor receptor 2 (HER2), have a poor prognosis. To overcome therapy limitations of TNBC, various new approaches are needed.
Idil, Cetin, Mehmet, Topcul
openaire   +4 more sources

Assessment of outcomes and novel immune biomarkers in metaplastic breast cancer: a single institution retrospective study

World Journal of Surgical Oncology, 2020
Background Metaplastic breast cancer remains poorly characterized given its rarity and heterogeneity. The majority of metaplastic breast cancers demonstrate a phenotype of triple-negative breast cancer; however, differences in clinical outcomes between ...
Evan Morgan, Anupama Suresh, Akaansha Ganju, Daniel G. Stover, Robert Wesolowski, Sagar Sardesai, Anne Noonan, Raquel Reinbolt, Jeffrey VanDeusen, Nicole Williams, Mathew A. Cherian, Zaibo Li, Gregory Young, Marilly Palettas, Julie Stephens, Joseph Liu, Amanda Luff, Bhuvaneswari Ramaswamy, Maryam Lustberg   +18 more
doaj   +1 more source

Characteristics of triple-negative breast cancer [PDF]

Journal of Cancer Research and Clinical Oncology, 2010
Triple-negative breast cancers (TNBC) neither express hormone receptors, nor overexpress HER2. They are associated with poor prognosis, as defined by low five-year survival and high recurrence rates after adjuvant therapy. Overall, TNBC share striking similarities with basal-like breast cancers (BBC), so a number of studies considered them being the ...
de Ruijter, Tim C., Veeck, Jurgen, de Hoon, Joep P. J., van Engeland, Manon, Tjan-Heijnen, Vivianne C.   +4 more
openaire   +3 more sources

miR-331-3p Suppresses Cell Proliferation in TNBC Cells by Downregulating NRP2

Technology in Cancer Research & Treatment, 2020
Purpose: Triple-negative breast cancer is characterized by fast progression with high possible for metastasis and poor survival. Dysfunction of microRNAs plays an important role in the initiation and progression of cancer.
Mingchuan Zhao PhD, Mengmeng Zhang PhD, Zhonghua Tao PhD, Jun Cao PhD, Leiping Wang PhD, Xichun Hu PhD, MD   +5 more
doaj   +1 more source