Breast-Conserving Surgery in <i>BRCA</i> Mutation Carriers: A Paradigm Shift Toward Individualized, Multidisciplinary Care. [PDF]
Cipolla C +8 more
europepmc +1 more source
Mass spectrometry‐based phosphoproteomics for mechanistic dissection of cancer signaling pathways and uncovering therapeutic vulnerabilities. ABSTRACT Protein phosphorylation is a central post‐translational modification regulating cellular signaling, frequently dysregulated in cancer.
Hirokazu Shoji +2 more
wiley +1 more source
The Sparrow (Modified Lazy-S) Incision: A Practical Alternative to Level 1 Oncoplastic Techniques in Breast-Conserving Surgery. [PDF]
Papila B, Velidedeoglu M.
europepmc +1 more source
RECURRENCE PATTERN FOLLOWING BREAST - CONSERVING SURGERY FOR EARLY BREAST CANCER
E Govindaraj +3 more
openalex +1 more source
Reversal of MPPa‐PDT Resistance in Osteosarcoma by Targeting ROCK2‐Mediated Autophagy
ROCK2 competes with MST1 to bind to the aa 28‐198 region of SAV1 and then regulates the Hippo pathway to affect autophagy, resulting in the resistance of OS to MPPa‐PDT. Targeted inhibition of ROCK2 by screening for J059‐0149 increases the sensitivity of osteosarcoma to MPPa‐PDT. ABSTRACT Osteosarcoma (OS) is a primary bone tumour that occurs mostly in
Xuan Yi +14 more
wiley +1 more source
Impact of surgical margins on local recurrence rates in breast-conserving surgery. [PDF]
Munusamy R +5 more
europepmc +1 more source
Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao +8 more
wiley +1 more source
Comparison of Surgical Outcomes of Breast-Conserving Surgery Performed Under Local and General Anesthesia. [PDF]
Thiviya S, Buraq A, Amit A.
europepmc +1 more source
0-19. Breast conserving surgery is appropriate for localised ductal carcinoma in situ
Ajeet Kumar Gandhi +4 more
openalex +1 more source
A novel kirkovirus may be associated with equine gastrointestinal disease
Abstract Background Many cases of equine enterocolitis are suspected to be infectious in nature, but no pathogen is identified in many cases. Objectives Perform next‐generation sequencing on faeces collected from cases of equine enterocolitis for the presence of novel viruses and determine if an identified novel virus is associated with cases of equine
Lillian M. B. Haywood +3 more
wiley +1 more source

