Results 101 to 110 of about 3,479,769 (339)
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Clinical-pathological features of an occult mixed mucinous male breast cancer. a case report [PDF]
, 2017 Mucinous carcinoma of the male breast is an uncommon malignant breast neoplasm and its diagnoses remain difficult. It is probably due to such a low rate of breast cancer cases that men tend to be diagnosed at an older age than women and with a later ...
Bonifacino, Adriana +7 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Anthropometry and body composition of 18 year old men according to duration of breast feeding: birth cohort study from Brazil [PDF]
, 2003 Objective: To assess the association between duration of breast feeding and measures of adiposity in adolescence. Design: Population based birth cohort study.
Cole, T.J., Treleaven, P., Wells, J.C.K.
core
Nature Reviews Disease Primers, 2019 Breast cancer is the most frequent malignancy in women worldwide and is curable in ~70-80% of patients with early-stage, non-metastatic disease. Advanced breast cancer with distant organ metastases is considered incurable with currently available therapies.
Harbeck, Nadia +8 more
openaire +5 more sources
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Video-Assisted Breast Conservation Surgery for Breast Cancer
Journal of Health Science and Medical Research (JHSMR), 2012 Breast conservation surgery (BCS) is the standard surgical treatment for early breast cancer. It produces equivalent oncologic outcome but better aesthetic result, psychological outcome and quality of life when compared with mastectomy.
Somrit Mahattanobon
doaj
Traits of tubular adenoma cytology
Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2018 Tubular adenoma of breast is a rare benign pure epithelial tumor, which presents as a palpable mass. Clinical examination and imaging modalities are similar to that seen in a case of fibroadenoma.
Manoj Gopal Madakshira +2 more
doaj +1 more source
Clinical utility of gadobenate dimeglumine in contrast-enhanced MRI of the breast: a review [PDF]
, 2015 Breast magnetic resonance imaging (MRI) is considered the technique with the highest sensitivity for breast cancer detection. Gadobenate dimeglumine is a gadolinium-based contrast agent (GBCA) that is specifically approved in Europe for breast MRI and ...
Kirchin, Miles +3 more
core +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source