Results 61 to 70 of about 2,803,405 (288)
Celecoxib decreases prostaglandin E\u3csub\u3e2\u3c/sub\u3e concentrations in nipple aspirate fluid from high risk postmenopausal women and women with breast cancer [PDF]
, 2006 Background Celecoxib inhibits PGE2 production in cancerous tissue. We previously reported that PGE2 levels in nipple aspirate fluid (NAF) and plasma were not decreased in women at increased breast cancer risk who received celecoxib 200 mg twice daily ...
Flynn, John T. +4 more
core +1 more source
Annals of Surgery, 1934 Abstract 1. 1. The histological grading of malignancies is not as generally accepted by pathologists as it is by surgeons. 2. 2. There are too many factors to be considered in such a grading to give any uniform opinion. 3. 3. Postoperative irradiation presents another disturbing factor in estimating any histological index. 4. 4.
openaire +5 more sources
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
European Journal of Breast Health, 2013 Breast carcinoma is the most common malignancy in women after skin cancer and, after lung cancer, the most frequent cause of cancer death in females.
Abut Kebudi
doaj +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
The Genomic Profile of Pregnancy-Associated Breast Cancer: A Systematic Review
Frontiers in Oncology, 2020 Breast cancer is the most common malignancy diagnosed during pregnancy. Strong data on the genomic profile of pregnancy-associated breast cancer are lacking.
Anna-Maria Korakiti +4 more
doaj +1 more source
Anthropometry and body composition of 18 year old men according to duration of breast feeding: birth cohort study from Brazil [PDF]
, 2003 Objective: To assess the association between duration of breast feeding and measures of adiposity in adolescence. Design: Population based birth cohort study.
Cole, T.J., Treleaven, P., Wells, J.C.K.
core
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
대한영상의학회지, 2017 Purpose To investigate the capability of enhanced chest computed tomography (CT) for detecting breast abnormalities and to assess the influence of breast composition on this detectability.
Eun Mi Cho +5 more
doaj +1 more source