Results 111 to 120 of about 1,426,705 (304)

Docetaxel rechallenge in HER2-negative metastatic breast cancer: a real-world study of previously discontinued patients for non-progression reasons

Journal of Cancer Research and Clinical Oncology
Purpose This study aimed to evaluate the efficacy and safety of docetaxel rechallenge in HER2-negative metastatic breast cancer (MBC) patients who discontinued docetaxel for reasons other than disease progression.
Hui-Ai Zeng, Hui-Min Lv, Meng-Wei Zhang, Li-Min Niu, Jing Wang, Hui-Hui Sun, Zhen-Zhen Liu, Min Yan   +7 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Guidelines for breast cancer diagnosis and treatment by China Anti-Cancer Association (2026 edition)

Zhongguo aizheng zazhi
According to the latest data released by the International Agency for Research on Cancer (IARC) of the World Health Organization (WHO), among women, breast cancer is the most common type of cancer and the leading cause of cancer-related deaths. Since the
The Society of Breast Cancer China Anti-Cancer Association, Breast Oncology Group of the Oncology Branch of the Chinese Medical Association   +1 more
doaj  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Breast Cancer Tissue Bank Blood Samples

This BCTB subcollection consists of blood samples taken from breast cancer patients and others. It is further broken down into a number of blood components.

core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Inetetamab plus camrelizumab and utidelone for pretreated HER2-positive advanced breast cancer: a prospective, single-arm, phase 2 study

BMC Medicine
Background The efficacy and safety of anti-HER2 therapy and immune checkpoint inhibitors combined with chemotherapy to treat HER2-positive advanced breast cancer that has failed standard HER2-directed therapies is unknown.
Huimin Lv, Tao Sun, Xiaoling Ling, Xinlan Liu, Jin Yang, Mengwei Zhang, Limin Niu, Shumin Chen, Zhenzhen Liu, Chengzheng Wang, Huihui Sun, Jing Wang, Huiai Zeng, Shengnan Zhao, Lanwei Guo, Yajing Feng, Zhiqing Zhang, Qingxin Xia, Rongguo Qiu, Min Yan   +19 more
doaj   +1 more source

Long-term effectiveness of adjuvant Goserelin in premenopausal women with early breast cancer

, 2009
BACKGROUND: Systematic reviews have found that luteinizing hormone-releasing hormone (LHRH) agonists are effective in treating premenopausal women with early breast cancer.
Fornander, T, S. Forsyth, Johansson, Ulla,, T. Fornander, U. Johansson, Reczko, Krystyna,, B. Nordenskjold, Nordenskjold, Bo, Fornander, Tommy,, K. Reczko, Reczko, Krystyna, Fohlin, H, Hackshaw, Allan, Fornander, Tommy, Fohlin, Helena,, Valentini, Miriam,, H. Fohlin, Sainsbury, R, Fohlin, Helena, Johansson, U, Monson, Kathryn,, Reczko, K, M. Valentini, Forsyth, Sharon, Sainsbury, Richard,, Nicolucci, A, Monson, K, R. Sainsbury, Baum, M, Sainsbury, Richard, Valentini, Miriam, A. Hackshaw, Nordenskjöld, Bo,, Forsyth, Sharon,, M. Baum, A. Nicolucci, Nordenskjold, B, Fornander, T,, K. Monson, Johansson, Ulla, Nicolucci, Antonio,, Baum, Michael,, Baum, Michael, Hackshaw, Allan,, Hackshaw, A, Valentini, M, Monson, Kathryn, Nicolucci, Antonio, Forsyth, S   +48 more
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Molecular characterization of pregnancy-associated breast cancer and insights on timing from GEICAM-EMBARCAM study

npj Breast Cancer
Pregnancy-associated breast cancer (PABC), diagnosed during or shortly after pregnancy, is a challenging entity with an aggressive biology and poor prognosis.
Regina Peña-Enríquez, Begoña Bermejo, Marina Pollán, Alejandra Díaz-Chacón, Yolanda Jerez Gilarranz, José J Ponce Lorenzo, Antonio Fernández Aramburo, Blanca Cantos Sánchez de Ibargüen, Ana Santaballa Bertrán, Elena Galve-Calvo, Álvaro Jiménez-Arranz, Yolanda Fernández, María Eva Pérez, Susana De La Cruz, Antonio Anton-Torres, Fernando Moreno, María Jesús Vidal-Losada, María Helena López-Ceballos, Isabel Blancas, María José Echarri, Raúl Rincón, Rosalía Caballero, Ángel Guerrero-Zotano, Silvia Guil-Luna, Juan de la Haba-Rodríguez   +24 more
doaj   +1 more source