Results 81 to 90 of about 4,221,746 (249)
Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers [PDF]
, 2012 <p>Introduction: Cis-acting regulatory single nucleotide polymorphisms (SNPs) at specific loci may modulate penetrance of germline mutations at the same loci by introducing different levels of expression of the wild-type allele.Susan M Domchek, Frost, D., Beesley, Jonathan, Beesley, J., Jonathan Beesley, Couch, Fergus J, Samarajiwa, S., Caligo, Maria A., Ponder, Bruce A. J., Barkardottir, Rosa B., Ponder, Bruce AJ, Caligo, Maria, Adelaide, Sue Healey, Swe-brca, Swe-brca, Easton, Douglas F, Adlard, Julian, Barkardottir, Rosa B, Embrace, Embrace, Peock, Susan, Domchek, Susan, Gauthier-Villars, Marion, Heli Nevanlinna, Godwin, Andrew, null null, Xiaoqing Chen, Caligo, Maria,, Laurence Faivre, Sinilnikova, Olga M, Domchek, Susan M., Domchek, Susan M, Samarajiwa, Shamith, Georgia Chenevix-Trench, O'Reilly, M., Barkardottir, R.B., Mark Dunning, Evans, D,, Evans, D.G., Chen, Xiaoqing, Godwin, Andrew K, Couch, Fergus, Ponder, Bruce, Carlos Caldas, Debra Frost, Evans, D. G.; id_orcid, Curtis, Christina, Kartsonaki, C., Eccles, Diana, Nevanlinna, Heli, Einbeigi, Zakaria,, Nevanlinna, H., Izatt, Louise, Healey, S., Caldas, Carlos, McGuffog, Lesley, Evans, D, Gareth, Peock, S., Martin O'Reilly, Evans, D Gareth, Christiana Kartsonaki, Laurence Venat-Bouvet, Ponder, Bruce A.J., Diana Eccles, Adlard, J., Faivre, L., Mazoyer, Sylvie, Olga M Sinilnikova, Antoniou, A.C., Kartsonaki, Christiana, Venat-Bouvet, Laurence, Susan Peock, Louise Izatt, Rosa B Barkardottir, Easton, Douglas, Delnatte, C., McGuffog, L., Tobias, E.S., Julian Adlard, Chenevix-Trench, Georgia, Frost, Debra, Easton, Douglas F., Curtis, Christina N, Antoniou, Antonis, Suet-Feung Chin, Barkardottir, Rosa, Marion Gauthier-Villars, Venat-Bouvet, L., Godwin, A.K., Lesley McGuffog, Caligo, Maria-Adelaide, Couch, Fergus J., Antoniou, Antonis C, Christina N Curtis, Chin, Suet-Feung, Antoniou, Antonis C., Caligo, M.A., Gemo, Gemo, Couch, F.J., Sylvie Mazoyer, Sinilnikova, Olga, Andrew K Godwin, Stoppa-Lyonnet, D., Caligo, Maria Adelaide, Bruce AJ Ponder, Eeles, R., Chin, Suet Feung, Ponder, Bruce A J, D Gareth Evans, Eccles, D., Chen, X., Chin, S.F., O'Reilly, Martin, Capucine Delnatte, Ana-Teresa Maia, Easton, D.F., Delnatte, Capucine, Douglas F Easton, Dunning, M., Godwin, Andrew K., Maria Adelaide Caligo, Ros Eeles, Chenevix-Trench, G., Caldas, C., Domchek, S.M., Antonis C Antoniou, Curtis, C.N., Sinilnikova, O.M., Curtis, Christina N., Ponder, B.A.J., Sinilnikova, Olga M., Mazoyer, S., Eeles, Ros, Dunning, Mark, Dominique Stoppa-Lyonnet, Maia, A.T., Faivre, Laurence, Gauthier-Villars, M., Healey, Sue, kConFab, kConFab, Maia, Ana-Teresa, Stoppa-Lyonnet, Dominique, Shamith Samarajiwa, Fergus J Couch, Evans, D. Gareth, Izatt, L., Maia, Ana Teresa, Antoniou, AC, Samarajiwa, S, Domchek, S. M. et al, Chin, S-F, Dunning, M, Chin, S. F., Domchek, SM, O'Reilly, M, Curtis, C. N., ?, ?, McGuffog, L, Maia, A. T., Maia, A-T, Kartsonaki, C, Curtis, CN, Antoniou, A. C. +160 morecore +15 more sourcesInhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli +10 morewiley +1 more sourceCirculating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong +6 morewiley +1 more sourceA case of radiation-associated angiosarcoma after breast cancer
Surgical Case Reports, 2018 Background Radiation-associated angiosarcoma (RAAS) is a rare subtype of secondary angiosarcoma that is characterized by rapid proliferation and extensive tissue infiltration.Nanae Horisawa, Yayoi Adachi, Masataka Sawaki, Masaya Hattori, Akiyo Yoshimura, Naomi Gondo, Haruru Kotani, Ayumi Kataoka, Kayoko Sugino, Makiko Mori, Mitsuo Terada, Yuri Ozaki, Hiroji Iwata +12 moredoaj +1 more sourceGenome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk [PDF]
, 2013 BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were Side, Lucy E.,, Investigators, k, Pastinen, Tomi, Van Os, Theo A.M., D. F. Easton (7608179), J. Balmana, Ute Hamann (89879), Volorio, Sara, A. Lasa, SWE-BRCA, Tihomirova, L, Imyanitov, E.N., Moeller, ST, L. Senter, Friedlander, M., Muy-Kheng Tea, Barrowdale, D., Öfverholm, Anna, Aittomaki, K., N. Tung, J. Lester, C. F. Singer (7619636), T. Huzarski (7676663), Douglas, F., Shimon Paluch, Shani,, Frans B L Hogervorst, Barkardottir, Rosa B, C. Houdayer (7658699), Pascal Pujol, Dreyfus, Hélène, H. Thorne, Murday, Victoria, Viel, Alessandra, Heli Nevanlinna, Rouleau, E, Shani Shimon Paluch (395262), Yuan Chun Ding (322601), de la Hoya, Miguel, P. Pujol, Capucine Delnatte (395234), Georgia Chenevix-Trench (361), Rita Katharina Schmutzler (395199), Paolo Peterlongo, Kerstin Rhiem (112049), Imyanitov, Evgeny N., Z. Miedzybrodzka, Bonanni, Bernardo, C. Lazaro, Adam Lee, Beattie, Mary S.,, Arnold, N, Caldes, Trinidad,, Dezheng Huo (151859), Sinilnikova, O. M., Pascaline Berthet (395233), J. Garber (7608110), Chung, Wendy K., Arver, Brita, Zachary Fredericksen (146612), Diana M. Eccles (219472), Pujol, P, Sand, S, A. E. Toland (7608026), Niederacher, D, A. Lucassen, Lubinski, Jan, D. E. Cohn (7676702), Tihomirova, L., Miguel de la Hoya, D. Gareth Evans (154186), Ausems, M. G E M, T. Pastinen (7608953), Marco Montagna (238698), Berthet, Pascaline, Taylor, Jane, L. Venat Bouvet, A. Meindl (7619555), Slager, Susan L, B. Bonanni (1681321), Weber, Bernhard HF, Brewer, C., Mulligan, A.M., Sabine Preisler-Adams (395251), Bernhard H. F. Weber (162289), Osorio, A, Hardouin, A, Pastinen, T., Peissel, Bernhard, Kristiina Aittomäki, Esther M John, Mazoyer, S, Friebel, T, Lidereau, Rosette, Blanco, I, Jonson, L, Gaudet, Mia M.,, Patrick J Morrison, Lee, A, Christian F. Singer (308365), Platte, Radke, M. C. Southey (7608080), Lenka Foretova (162255), Platte, Radka, Liljegren, Annelie, Huzarski, Tomasz, Tibiletti, MG, Lebrun, Marine, K. Kohut, Spurdle, Amanda B, Y. Laitman (7608005), Pujol, Pascal,, Ewart Toland, A., M. Tischkowitz, Alexandra V. Stavropoulou (387774), O. Caron, C. Seynaeve, S. V. Blank, Jan Lubinski (59925), C. M. Kets, Berthet, P., L. Snadden, Daphne Gschwantler-Kaulich, A. Romero (3572522), J. Benitez, Wijnen, JT, Singer C.F., Guimbaud, Rosine, Susan L Neuhausen, Frans B. L. Hogervorst (146390), D. Frost, Mortemousque, Isabelle, Coupier, Isabelle,, F. Prieur, et al., Ignacio Blanco, Donaldson, A, M. Lebrun, E. Castro, A. M. Mulligan, Peissel, Bernard,, Fredericksen, Z, Pujana, Miquel Angel, Zakaria Einbeigi, Andrea Gehrig, Stoppa-Lyonnet D., Eeles, RA, Teo, Soo-Hwang,, M. J. Blok, C. Nogues (2482849), E. Niedermayr, Handallou, Sandrine, Wiggins, Jennifer, Kwong, A., Varon-Mateeva, R, Olopade, O.I., C. Engel (7619549), R. Platte (7608131), Kruse, Torben A, Maria Grazia Tibiletti (395246), Cunningham, Julie, Leone, Melanie,, S. Hart, Kristiina Aittomäki (89889), Kuchenbaecker, K. B., Montagna, M., Tomasz Huzarski, Dennis, Joe,, Robson, Mark,, A. Gehrig (7676681), van Asperen, C. J., K. Jaworska, Gadzicki, D., Mette K. Andersen (395271), Lindor, Noralane M, David E Cohn, Vincent, Daniel,, Pankratz, Vernon S, Mia M. Gaudet (146621), Soucy, Penny, E. Fineberg (7658291), Blok, Marinus J.,, Raymonda Varon-Mateeva, S. A. Narod, Rouleau, Etienne,, G. Glendon, Jernström, Helena, Sokolowska, Johanna, Moeller, S, Pujana, M.A., Uhrhammer, Nancy, Haque, Eshika, Buys, SS, Kruse, T.A., Ligtenberg, Marjolijn JL, Vijai, Joseph,, D. Mcbride, T. M. Friebel, M. K. Tea (7619639), Robson, Mark, S. M. Domchek, Sue Healey, A. Murray, Gerdes, Anne-Marie, Jaworska, Katarzyna,, Kara Sarrel, Douglas, Fiona,, Hall, Per, Rookus, M. A., L. Foretova (7676744), S. R. Sand, Lindblom, Annika, Laurie Small, Toulas, Christine, A. M. Dunning (7658231), Adlard, Julian,, Ottini, Laura,, Verhoef, S, Janavicius, R, R. Rosenquist (7652192), Prieur, Fabienne, Nogues, Catherine, S. T. Moeller, Hodgson, Shirley,, Morrison, Patrick J., L. E. Side, D. Huo (7676804), Godwin, Andrew K, C. Toulas, Christian Sutter, J. Adlard (7619510), Meindl, A, Hart, Steven,, Shimon Paluch, S, Mai, Phuong L, F. Bacot (7658246), F. Prieur (7658807), Venat-Bouvet, Laurence,, Szabo, C.I., Kathleen Claes (203063), G. Pfeiler (7658321), Goldgar, David E, Os, T.A. van, Sharon R Sand, Evans, Gareth; id_orcid, Ehrencrona, Hans, Susan J Ramus, A. Donaldson (6262271), Kruse, T, A. Hardouin, Sharon R. Sand (395278), Karin Kast (112042), H. T. Lynch, Barkardottir, R, Z. Fredericksen (7619612), Andersen, MK, Southey, Melissa C., Jaworska, K., Gaudet, MM, Ligtenberg, MJL, Jocelyne Chiquette, M. Porteous, Lars Jønson (395270), Inge Sokilde Pedersen, Tara M. Friebel (395289), A. P. Sokolenko (7676810), Isabelle Coupier (292499), S. Goff, M. J. Blok (7658489), Rosa B Barkardottir, O. Diez (7676606), Ellis, S, Drummond, Sarah, Anna Marie Mulligan (146672), Gerdes, Anne-Marie,, Domchek, SM, Izatt, Luise, Douglas F. Easton (89956), Catherine M. Phelan (219497), Traasdahl Moeller, Sanne, Frans B. L. Hogervorst, L. Varesco (7676669), Melissa C Southey, Os, T. A.,, Christine Lasset, Laurence Venat-Bouvet (395240), Mélanie Léoné (395241), Sinilnikova O.M., S. Goodman, Bubien, Virginie, N. Tung (7608077), Tung, Nadine,, K. Sarrel, Paluch, Shani Shimon, Muranen, TA, Ausems, M.G., Marc Tischkowitz, Szabo, Csilla I, G. Dite, Jacqueline Eason, Hogervorst, F.B., Gomez Garcia, E.B., L. Side, Laurie Small (395257), A. K. Godwin (7608119), Tibiletti, M, I. Blanco, K. Rhiem (7619546), Laitman, Y., Borg, Åke, Kosel, Matthew, Sutter, C., M. G. E. M. Ausems, Anne-Marie Gerdes, S. Preisler Adams, Stefanie Engert (112037), A. V. Stavropoulou (7676780), Chen, Wang, Finn C Nielsen, V. S. Pankratz, Piedmonte, Marion,, V. Bubien, Gibson, Sarah, Coupier, I., N. Ditsch, Hogervorst, Frans B L, M. Leone, K. Durda (7676657), Mads Thomassen, Ellis, Ian, Meindl, Alfons,, Dicks E., Wendy K Chung, M. Soller, Mazoyer, S., Devilee, Peter,, Pastinen, Tomi,, B. Arver (7619687), Gadzicki, D, Jakubowska, Anna,, Searle, Anne, Alexander Miron (28179), J. Cunningham (7676831), C. Jacobs, Fergus J Couch, A. De Pauw, S. B. Chan, Eitan Friedman (196582), Hansen, TV, Rensburg, E. J.,, McLeod, Diane, Neuhausen, Susan L.,, Alison M. Dunning (146796), Terry, MB, M. Piedmonte, Złowocka-Perłowska, Elżbieta, Hansen, TVO, S. L. Slager, Vijai, Joseph, Antoniou, AC, Dorfling, C.M., L. E. Side (7619534), T. Noguchi, Złowocka-Perlowska, Elz bieta, Pujol, Pascal, Olswold, C, S. Giraud, Hansen, T.V.O., Ava Kwong (52115), J. Simard, Feillel, Viviane, Antoniou, A., Nogues, C., Mary S Beattie, Domchek, S, Adlard, Julian, M. B. Daly (7608074), Laitman, Yael,, Frost, D, Silvia Tognazzo (395279), D. Stoppa-Lyonnet (7608194), S. J. Ramus (7608041), Neuhausen, S, Cook, J., M. K. Schmidt, Wang, Xianshu, Ottini, L, Blank, Stephanie V., Karlan, BY, B. Peissel (7619426), J. De Lange, Schmutzler, R. K., Benitez, Javier, Papi, L., F. E. van Leeuwen (7658432), Grazia Tibiletti, Maria,, Ontario Canc Genetics Network, Volorio, S., T. C. T. E. F. Van Cronenburg, Lee, A., Kristoffersson, Ulf, Lenka Foretova, Nielsen, FC, Jonson, L., A. Osorio (7608089), Miquel Angel Pujana (395274), Finn C. Nielsen (206969), Mulligan, AM, Dieter Niederacher (93623), Teo, S.H., Slager, SL, H. Ozcelik (7608029), Angel Pujana, Miquel, EMBRACE (Epidemiological Study of Familial Breast Cancer), Pascal Pujol (8444), Sandra Orsulic, G. Rea, P. Hall (7508258), Izatt, Louise, Huo, D., Southey, M. C., Kaufman, B, Pensotti, Valeria, Jenny Lester (395276), Pfeiler, Georg, Beth Y. Karlan (184236), Sutter, C, Kientz, Caroline, Manoukian, Siranoush,, Longmuir, Mark, T. M. Friebel (7676819), Ganz, P.A., M. J. Kennedy, N. Loman (7676693), Weaver, Joellen, T. Huzarski, E. Olah, S. Hodgson (7633343), Stephanie V Blank, Bernhard H F Weber, Sokolenko, Anna P., Huo, DZ, Houghton, Catherine,, Ontario Cancer Genetics Network, Durda, K., J. T. Wijnen (7658285), C. Rappaport (7676717), Teule, Alex, Hamann, Ute, Pujana, MA, Singer, Christian F, Norbert Arnold, Dennis, Joe, H. Nevanlinna, S. Shimon Paluch (7676723), Rouleau, Etienne, Theo A. M. van Os (395220), Peissel, Bernard, Blanco, I., Buys, S, Stenmark-Askmalm, M., H. Gregory, Miron, A., Orsulic, Sandra,, Ganz, PA, Narod, S.A., Nadine Tung (238710), Ramus, S.J., van Rensburg, Elisabeth J., N. Sevenet, B. H. Weber (7676690), J. Dennis (7658234), Gregory, Helen,, Annemarie H van der Hout, Alexander Miron, Chun Ding, Yuan, C. H. van Deurzen (7676618), Kruse, Torben A.,, Y. C. Ding (7619387), Weaver, J, Flora E. van Leeuwen (248404), Raymonda Varon-Mateeva (196729), van Os, Theo AM, Ramus, Susan J, E. Rouleau (7658759), Noah Kauff, Rosenquist, Richard,, Blok, M.J., E. B. Gomez Garcia, Lasset, C, C. Berlin, Cohn, D.E., Caroline Seynaeve, Arun, Banu K, Trinidad Caldes, Soucy, Penny,, van Leeuwen, Flora E, S. B. Chan (7676807), Hall, P., van Deurzen, C, Walsh, C, Jeffrey N. Weitzel (238722), Francesca Damiola, Soller, Maria, Hansen T.V.O., N. Kauff (7619633), Joe Dennis, Agnès Hardouin, Hansen, Thomas VO, Engert, Stefanie, K. Offit, B. H. F. Weber, L. Izatt (7608137), M. K. Andersen, Vincent, D., Mary Beth Terry (2801), Karin Kast, Friedman E., J. P. Fricker, Huw Dorkins, Olufunmilayo I. Olopade (151873), Aittomäki, K, Hogervorst, FB, Hilmi Ozcelik (20185), Huo, Dezheng, Stenmark-Askmalm, M, S. H. Teo (7675199), Pedersen, IS, M. Belotti, Bent Ejlertsen, Teule, A., Encarna B. Gómez Garcia (5654410), Olah, E., C. M. Phelan, Jacqueline Eason (238727), Montagna, M, I. S. Pedersen (7676726), Ejlertsen, B, E. Friedman (7608035), Anneliese Fink-Retter, L. Foretova, Friedman, Eitan,, Peterlongo, Paolo,, Beattie, MS, Engert, Stefanie,, Spurdle, Amanda B.,, Steven A. Narod (230773), E. N. Imyanitov (7676600), Jackie Cook, al., et, Rosalind A Eeles, K. Henriksson, Rebbeck, Timothy R.,, van Deurzen, Carolien H. M., F. B. Hogervorst (7608212), Wijnen, J.T., Barbara Wappenschmidt, Meindl, Alfons, Eitan Friedman, Blank, Stephanie V, S. Shimon Paluch, Timothy R. Rebbeck (230766), Lazaro, Conxi, Olah, E, Radice P., Zlowocka-Perlowska, E, Jensen, U, Agata, S, Orsulic, S., Ejlertsen, Bent,, F. Douglas (7658597), Kristen Stevens, Eason, J, Soucy, P., B. Bressac De Paillerets, James, Margaret, Paolo Radice (146601), E. Zlowocka Perlowska, Gille, JJP, Hansjoerg Plendl (395250), Złowowcka-Perłowska, Elzbieta, L. Small, Ausems, Magreet G. E. M., Paluch, SS, Friebel, TM, Conxi Lazaro (3405329), Daly, Mary B.,, Vaszko, T, C. Sutter, Agnès Hardouin (395232), Friebel, T.M., Preisler-Adams, S., Glendon, Gord, Greene, M.H., Marinus J. Blok (395217), Nevanlinna, H., Hoya, M. de la, Yves-Jean Bignon (54433), I. L. Andrulis (7608020), von Wachenfeldt, Anna, Lars Jønson, Sutter, Christian,, McGuffog, Lesley, Karlan, B. Y., Fabienne Prieur (246641), Lazaro, C (Conxi), Hilmi Ozcelik, Bacot, Francois,, Collaborators, GEMOS, Bourdon, Violaine, Lee, Andrew, Jensen, UB, Herzog, J, Bacot, Françios, Lucassen, Anneke, Simard, Jacques,, Friedlander, Michael, Theo A M van Os, Xianshu Wang (146610), Olga M Sinilnikova, Steele, L, Waisfisz, Q., Platte, R, Lubinski, Jan,, C. Tirapo, Meijers-Heijboer, H. E., Bacot, F., Blank, SV, A. Calender, Singer, CF, Joan Brunet (75020), M. Kosel (7676585), A. Brady, Hanne E J Meijers-Heijboer, Einbeigi, Z, Blanco, Ignacio, A. P. Sokolenko, Penny Soucy (21792), Andrulis, IL, Steele, L., Weber, B.H., Caroline Seynaeve (95368), Singer, Christian F.,, S. M. Domchek (7608044), Evans, Gareth D., Loud, J.T., Domchek S.M., Anne-Bine Skytte (395263), Hart, Steven, Rappaport, C, Szabo, C. I., M. Emanuelsson, Tea, Muy Kheng, Gille, JJ, J. Paterson, Ausems, Margreet GEM, Ava Kwong, Judith Balmaña (395210), Demange, Liliane, Goldgar, D, Ramus, Susan J., Thomas V O Hansen, Sylvie Mazoyer, S. Manoukian, Dorfling, CM, Loman, N., N. M. Lindor (7619618), Preisler-Adams, Sabine, Pankratz, V.S., Martin, Sue, Hansen, Thomas V O, Goldgar, DE, N. M. Lindor, Sobol, Hagay, Easton, D.F., O. I. Olopade (7607978), Castera, L., Sabine Preisler-Adams, Cunningham, J, O. I. Olopade, Jonson, Lars,, S. Agata, C. Houghton, J. T. Loud, Chenevix-Trench, G., Curtis Olswold (73571), Kulkarni, Anjana, Ausems, MGEM, Sinilnikova, O.M., J. Chiquette, Glendon, G, Ding, Y.C., S. Tognazzo (7619591), Imyanitov, EN, Wang X., Anneliese Fink-Retter (395258), M. H. Greene (7608092), Muranen, T.A., J. Herzog (7676765), Ellis, Steve,, S. Handallou, kConFab Investigators, C. Lasset, M. Stenmark Askmalm, Fournier, Joëlle, Montagna, Marco,, Christoph Engel, Edith Olah (395204), Bignon, Y, Kets, C. M., D. Yannoukakos, J. Maskiell, C. Brewer (7658534), Kenneth Offit (63812), van Rensburg, E, Kauff, N., D. Frost (7608128), Ausems, M.G.E.M., Lehmann, Anna, X. Wang (770484), A. Ewart Toland, Garcia, EBG, Andrulis, Irene L, V. L. Bae-Jump (7676714), Zachary Fredericksen, Elena Fineberg, Side, Lucy, Prieur, Fabienne,, Carole Brewer, Senno Verhoef (395219), T. A. Kruse (6179165), de Pauw, Antoine, HEBON (Hereditary Breast and Ovarian Cancer Research Group Netherlands), Dunning, A.M., Karlan, Beth Y, Piedmonte, M, A. Osorio, E. Kivuva, Orsulic, Sandra, van Rensburg, EJ, Moeller, S.T., J. M. Collee, van Leeuwen, F.E., Stormorken, Astrid, Marc Tischkowitz (395208), A. V. Stavropoulou, Josef Herzog (395277), Osorio, Ana, Soo-Hwang Teo (266270), Offit, Kenneth, Dicks, Ed,, Hogervorst, F. B L, Ozcelik, Hilmi,, Vaszko, Tibor, Murray, Alexandra, Debra Frost, Stevens, Kristen,, Orland Diez (395209), Phuong L. Mai (238716), Ramus, Susan J.,, Mercedes Duran, van Rensburg, E.J., Sobol, Hagay,, D. Vincent (2350123), Janavicius, Ramunas, Barrowdale, D, Brady, Angela, Beattie, M, Jaworska, K, Steve Ellis, P. A. Ganz (7619606), Kast, K., A. B. Skytte, Spurdle, AB, Soucy, P, Chung, W.K., Sarrel, Kara,, D. E. Cohn, Gaudet, M. M., Beattie, M. S., Elena Fineberg (395222), Senter, L, P. Peterlongo, F. Soubrier, Hagay Sobol, Evans, DG, Healey S., Ardern-Jones, Audrey, Sara Volorio (255289), Nadine Tung, Prieur, F, Joe Dennis (395193), S. Smalley, Nathanson, Katherine L.,, Hamann, Ute,, Rookus, Matti A.,, Valeria Pensotti (395247), S. Mazoyer, Weber, BHF, A. Melville, Josef Herzog, Nina Ditsch, Terry, M. B., K. Kast (7619507), Phelan, Catherine M.,, Neuhausen, Susan L., de Lange, J., Christian Sutter (196732), Miron, A, Mercedes Duran (5651374), Bignon, Yves-Jean,, Olufunmilayo I Olopade, Greene, Mark H.,, Agata, S., Isabelle Coupier, Gille, Johannes J.P., J. T. Wijnen, Mulligan, A, Engel, Christoph,, Hodgson, Shirley, Melin, Beatrice, Shirley Hodgson, Alex Murray (395230), L. Tihomirova (7676816), Fineberg, E., Antoniou, Antonis C, Andrew Lee (74302), C. Delnatte, A. Liljegren, Dorfling, Cecilia M.,, M. Piedmonte (7607933), Rogers, M.T., Paterson, Joan, Hogervorst, FBL, M. Duran, L. Winchester, Dennis, J, K. Hill, Thomassen, Mads,, K. Kast, N. Rahman, van Leeuwen, F. E., Capucine Delnatte, Nielsen, F, BCFR, Mazoyer, Sylvie,, M. Gauthier Villars, Trinidad Caldes (3147195), Gaudet, Mia M, Evgeny N Imyanitov, M. G. Tibiletti, Venat-Bouvet, L, K. Aittomaki, Gerdes, A.-M., Angel Pujana, Miquel,, Richard Rosenquist (262592), Stavropoulou, Alexandra V., Side, Lucy E., Mary B. Daly (196724), M. A. Pujana (7676753), Kruse, TA, Tihomirova, Laima, Mourits, M. J., Preisler-Adams, S, James, Paul A, Richard Rosenquist, Weitzel, Jeffrey N, Faivre, Laurence, Ellis, Steve, Leone, M., Kenneth Offit, M. B. Daly, Mai, P.L., Kuchenbaecker, Karoline B.,, Walker, Lisa, V. Attard, Marion Piedmonte, Eeles, R. A., B. Stayner, Jeffers, Lisa, L. Castera (7676645), Susan M. 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Ramus (205214), Devilee, Peter, Tripathi, Vishakha, Bignon, Y.J., Taru A. Muranen (395284), Karlan, B, Vincent, D, van Rensburg, Elizabeth J, Peissel, B., Hagay Sobol (91961), Daly, M. B., S. Preisler-Adams (7619522), Gehrig, Andrea,, Leroux, Dominique, Tischkowitz, M., C. E. Ardnor, Aalfs, C. M., Glendon, G., Lindor, Noralane M.,, Fergus J. Couch (146607), Angel Pujana, M., M. S. Beattie, B. A. Agnarsson (7676822), Lasset, Christine, T. R. Rebbeck, Blanco, Ingnacio, Stenmark-Askmalm, Marie, Castro, Elena, Louise Izatt, N. Ditsch (7676684), Kosel, M, Sara Volorio, Dorfling, Cecilia M, Antonis C. Antoniou (146788), David E. Cohn (395255), Damiola, Francesca, Andersen, M, Lasa, Adriana, G. Crawford, Mary S. Beattie (395206), Rouleau, E., Amanda Ewart Toland (164514), Katarzyna Jaworska (146755), Balmana, J., Durda, Katarzyna,, Couch, Fergus J., SWE-BRCA (7619690), Buys, Saundra S., Ramus, SJ, A. Searle, B. Bonanni, Remenieras, Audrey, R. B. Barkardottir, Houghton, C, Laitman, Y, J. Cunningham, Douglas, Fiona, Yannoukakos, D, S. Volorio, Karoline B. Kuchenbaecker (395191), Szabo, C, D. Eccles, Loud, Jennifer T, Georgia, Chenevix-Trench, Houlston, Richard, Montagna, Marco, Duran, M, Hamann, U., van Os, Theo A. M. +999 morecore +4 more sourcesCancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia +15 morewiley +1 more sourceEpigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun +9 morewiley +1 more sourceMetabolomics assisted by transcriptomics analysis to reveal metabolic characteristics and potential biomarkers associated with treatment response of neoadjuvant therapy with TCbHP regimen in HER2 + breast cancer
Breast Cancer ResearchBackground This study aimed to explore potential indicators associated with the neoadjuvant efficacy of TCbHP regimen (taxane, carboplatin, trastuzumab, and pertuzumab) in HER2 + breast cancer (BrCa) patients.Ningning Zhang, Yuxin Huang, Guanwen Wang, Yimei Xiang, Zhouhong Jing, Junjie Zeng, Feng Yu, Xianjun Pan, Wenqi Zhou, Xiaohua Zeng +9 moredoaj +1 more source
