Results 261 to 270 of about 9,188,168 (301)
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Archives of Surgery, 1986
To the Editor.—We were disturbed to read the discussion on breast cancer risk in the article by Bland et al1in the February 1986 issue of theArchives. As a geneticist who specializes in breast cancer risk analysis and a surgeon who has held in-depth discussions with women about risk for many years, we are concerned that this article will result in a ...
P T, Kelly, P R, Westdahl
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To the Editor.—We were disturbed to read the discussion on breast cancer risk in the article by Bland et al1in the February 1986 issue of theArchives. As a geneticist who specializes in breast cancer risk analysis and a surgeon who has held in-depth discussions with women about risk for many years, we are concerned that this article will result in a ...
P T, Kelly, P R, Westdahl
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Familial Cancer, 2005
BAP1 whose protein interacts with BRCA1 was analysed in a series of 47 French familial breast cancer cases negatively tested for BRCA1/2 mutations. The lack of detection of deleterious mutations suggests that BAP1 is not a high risk breast cancer predisposing gene.
Isabelle, Coupier +6 more
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BAP1 whose protein interacts with BRCA1 was analysed in a series of 47 French familial breast cancer cases negatively tested for BRCA1/2 mutations. The lack of detection of deleterious mutations suggests that BAP1 is not a high risk breast cancer predisposing gene.
Isabelle, Coupier +6 more
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Nature Genetics, 2012
Many SNPs associated with human disease are located in non-coding regions of the genome. A new study shows that SNPs associated with breast cancer risk are located in enhancer regions and alter binding affinity for the pioneer factor FOXA1.
Kerstin B, Meyer, Jason S, Carroll
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Many SNPs associated with human disease are located in non-coding regions of the genome. A new study shows that SNPs associated with breast cancer risk are located in enhancer regions and alter binding affinity for the pioneer factor FOXA1.
Kerstin B, Meyer, Jason S, Carroll
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Breast Density and the Risk of Breast Cancer
New England Journal of Medicine, 2002There is great variation among women in the density of breast parenchyma as seen on mammograms. Mammographic density also varies inversely with age. Thus, younger women tend to have denser breasts than older women, but many older women also have dense breasts.
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Prolactin and breast cancer risk
Cancer Letters, 2006Prolactin, a hormone involved in normal breast development and lactation, has been hypothesized to be important in the etiology of breast cancer. This review summarizes in vitro, animal, and epidemiologic data supporting this hypothesis. Experimental evidence indicates that prolactin can promote cell proliferation and survival, increase cell motility ...
Shelley S, Tworoger, Susan E, Hankinson
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Prolactin and breast cancer risk
Medical Journal of Australia, 1990A study of 424 women was undertaken to determine whether there was an association between serum prolactin levels and breast cancer; whether prolactin levels would reflect degrees of risk of developing breast cancer; and whether associations between known risk factors for breast cancer and serum prolactin concentrations could be demonstrated.
D M, Ingram, E M, Nottage, A N, Roberts
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Risk assessment for breast cancer
European Journal of Cancer Prevention, 2015Cancer prevention and treatment are among the greatest challenges for health care systems worldwide nowadays (Zatonski, 2003). Primary prevention constitutes a serious challenge because of the multitude and diversity of factors playing a role in carcinogenesis.
Beata, Pięta +2 more
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Nutrition and Cancer, 1997
Data from a multicenter case-control study on breast cancer conducted in Italy were used to analyze the relationship between various types of fibers and breast cancer risk. Cases were 2,569 women with histologically confirmed, incident breast cancer; controls were 2,588 women admitted to the same network of hospitals for acute, nonneoplastic, non ...
C. La Vecchia +5 more
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Data from a multicenter case-control study on breast cancer conducted in Italy were used to analyze the relationship between various types of fibers and breast cancer risk. Cases were 2,569 women with histologically confirmed, incident breast cancer; controls were 2,588 women admitted to the same network of hospitals for acute, nonneoplastic, non ...
C. La Vecchia +5 more
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Assessing the Risk of Breast Cancer
New England Journal of Medicine, 2000Each year in the United States, breast cancer is diagnosed in more than 170,000 women.1 Despite this substantial burden of disease, however, assessment of breast-cancer risk has received very little attention outside the oncology clinic.2,3 In primary care, the main result of the recognition of individual variation in breast-cancer risk is the use of ...
K, Armstrong, A, Eisen, B, Weber
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Reducing the Risk of Breast Cancer
New England Journal of Medicine, 2000Recent research results suggest that the risk of breast cancer can be reduced. In this review I will focus on chemoprevention, emphasizing evidence from randomized clinical trials, and in addition summarize the evidence regarding preventive strategies involving surgery and lifestyle changes (Table 1).
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