Results 51 to 60 of about 9,188,168 (301)
Obesity and breast cancer risk [PDF]
Human Reproduction, 1997 Being overweight appears to be associated with a higher risk of post-menopausal breast cancer in most studies. Although the relative risk of breast cancer related to Quetelet's index is generally weak (range 1.1-1.9 in the major cohort studies), some studies have found that timing of weight gain and body fat distribution could be more significant ...P, Pujol, F, Galtier-Dereure, J, Bringeropenaire +2 more sourcesGenetic variants at chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 influence the risk of breast cancer in men. [PDF]
, 2011 Male breast cancer accounts for approximately 1% of all breast cancer. To date, risk factors for male breast cancer are poorly defined, but certain risk factors and genetic features appear common to both male and female breast cancer.Orr, Nick, Katarzyna Tomczyk, Dudbridge, Frank, Rosie Cooke, Michael Jones, Houlston, Richard, Alan Ashworth, Swerdlow, Anthony, Jones, Michael, Fletcher, Olivia, Cooke, Rosie, Frank Dudbridge, Richard Houlston, Chilcott-Burns, Sarah, Broderick, Peter, Olivia Fletcher, Anthony Swerdlow, Sarah Chilcott-Burns, Ashworth, Alan, Tomczyk, Katarzyna, Nick Orr, Peter Broderick, Houlston Richard, Orr Nick, Chilcott-Burns Sarah, Cooke Rosie, Dudbridge Frank, Swerdlow Anthony, Fletcher Olivia, Ashworth Alan, Broderick Peter, Jones Michael, Tomczyk Katarzyna +32 morecore +1 more sourceNeutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang +8 morewiley +1 more sourceBreast cancers arising in high mammographic density tissue harbor tumor-promoting immune profiles
npj Breast CancerEpidemiological studies have shown that high mammographic density (HMD) is a strong risk factor for breast cancer (BC) and is associated with poor prognosis.Dane Cheasley, Meagan Ruppert, Lisa Devereux, Madawa W. Jayawardana, Qihong Zhao, Carolyn Nickson, Melrine Pereira, David J. Byrne, Stephen B. Fox, Ian G. Campbell, Kara L. Britt +10 moredoaj +1 more sourceEvaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk. [PDF]
, 2011 BACKGROUND: Somatic mutations in phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) are frequent in breast tumours and have been associated with oestrogen receptor (ER) expression, human epidermal growth factor receptor-2 overexpression, lymph ...Dite, G S, S Chanock, Noh, D-Y., Severi, G., Sangrajrang, S., Hein, R, Yoo, K-Y, J Wang, Wang, J., Pooley, K A, Anton-Culver, H., Rogov, Y.I., A Ziogas, Hein, A, Kosma, V.M., Brock, I W, S Manoukian, Meindl, A., S Sangrajrang, Dunning, A.M., R L Milne, Bartrar, CR, R Winqvist, S S Cross, Perez, J.I.A., Anton Culver, H., Ekici, A. B., Garcia Closas, M., Noh, D.Y., G G Giles, M W Beckmann, Silva, I. dos Santos, Hopper, JL, Broeks, A., Vachon, C M, N Johnson, Hopper, J L, Humphreys, M K, Bruening, T., Wang-Gohrke, S., Tollenaar, Robert A. E. M., Cross, SS, Kosma, V-M, Johnson, N., Bonanni, B, Milne, R L, Vachon, CM, M Bremer, Sawyer, E, Kataja, V, Mulligan, A.M., Easton, D F, Kosma, V-M., Chenevix Trench, G., P Schürmann, A Miron, L Baglietto, Miron, A, Lindblom, A., E M John, I W Brock, McKay, J, Kang, D., Bogdanova, N, Johnson, N, Apicella, C., Garcia-Closas, M., Van 't Veer, L. J., Hartikainen, J, Pylkaes, K., G S Dite, P Brennan, Hopper, J. L., Van 't Veer, LJ, Pooley, KA, Fredericksen, Z, Milne, R.L., Hopper, J.L., Cox, A, Pooley, K. A., Hillemanns, P., Wang-Gohrke, S, Kerin, M.J., John, E M, Rogov, Y. I., Zalutsky, J. V., Olson, J, McLean, CA, Anton-Culver, H, G D Thomas, Pooley, K.A., Hunter, D J, Grip, M, V-M Kosma, A Meindl, X Wang, N Bogdanova, BAGLIETTO, LAURA, Tomlinson, I, E Sawyer, Giles, GG, A M Dunning, Antonenkova, N, Pérez, JA, Schmidt, M K, Giles, G G, N Antonenkova, B Bonanni, Pharoah, P.P., Southey, M C, Chenevix-Trench, G, Invest, kConFab, GENICA Network, Schmidt, M. K., Hunter, DJ, Knight, J.A., Ko, YD, Mulligan, A M, Baglietto, L, Rogov, YI, V Gabrieau, Couch, FJ, Beckmann, M W, Knight, J A, Fasching, PA, J Peto, Meindl, A, Severi, G, Gibson, L., Burwinkel, B., Y I Rogov, Benítez, J, J McKay, Tomlinson, Ian, John, E. M., P P Pharoah, Lissowska, J, Noh, DY, Brüning, T., D-Y Noh, Glendon, G., Peterlongo, P, Noh, D. Y., Fredericksen, Z., Milne, RL, Beckmann, MW, Cross, S.S., Kosel, M, Manoukian, S., Schürmann, P, Chanock, S., Cerhan, J, Jukkola-Vuorinen, A, Fasching, P A, Australian Ovarian Cancer Study Group, Hoover, R. N., Vachon, C. M., I Andrulis, Rogov, Y I, Schmidt, M.K., H Anton-Culver, Dörk, T., P Hillemanns, Giles, G.G., Ekici, A B, Hoover, R.N., Schmutzler, RK, F J Couch, Australian Ovarian Cancer Study Gr, Peto, J., C Apicella, Couch, F.J., Hillemanns, P, Mannermaa, A., Brock, I.W., J Chang-Claude, Pylkäs, K, Van 't Veer, L.J., Cross, S. S., Chen, X, Winqvist, R, Hamann, U., Chang-Claude, J., Brennan, P, Baglietto, L., Kosma, V. M., Beckmann, M. W., Veer, L.J. van 't, Wang, X., kConFab Invest, Van T Veer, LJ, Van 't Veer, L. J., Dite, GS, S Margolin, Couch, F J, Jukkola-Vuorinen, A., Bartrar, C R, Dörk, T, Bremer, M, Hein, A., Dunning, A M, D Kang, D J Hunter, Manoukian, S, González-Neira, A, Doerk, T., Benitez, J., Thomas, GD, Sawyer, E., Hamann, U, T Dörk, V Kataja, Thomas, G. D., Dunning, A. M., Milne, R. L., I dos Santos Silva, Ko, Y D, A González-Neira, Tomlinson, I., Zalutsky, J V, M Grip, McLean, C A, Apicella, C, Gonzalez-Neira, A., Schmutzler, R. K., Pharoah, P P, null null, I Tomlinson, G Glendon, Stevens, K N, L J Van ‘t Veer, Schuermann, P., R N Hoover, Mclean, C. A., John, EM, Bartrar, C.R., Hunter, D.J., Mulligan, AM, C R Bartrar, Wang, J, Fasching, P.A., Ekici, A.B., Southey, M. C., Van ‘t Veer, LJ, Ziogas, A, Zalutsky, JV, Lissowska, J., Wang, X, Hoover, RN, M Garcia-Closas, Dunning, AM, Broeks, A, Burwinkel, B, Brock, IW, John, E.M., Easton, DF, Knight, J. A., M K Humphreys, Antonenkova, N., J A Knight, Tollenaar, RAEM, Kang, D, Mulligan, A. M., Kerin, M. J., Chang Claude, J., K-Y Yoo, M C Southey, Giles, G. G., Miron, A., Olson, J., Vachon, C.M., Humphreys, MK, Southey, M.C., S Wang-Gohrke, Chang-Claude, J, J Olson, Sangrajrang, S, Mckay, J., A Cox, Silva, I.D.S., V S Pankratz, Brennan, P., A B Ekici, Noh, D-Y, Jukkola Vuorinen, A., X Chen, Bremer, M., Ziogas, A., Pankratz, V. S., G Elliott, Schmutzler, R.K., Cerhan, J., Ekici, AB, Group, AOCS, Couch, F. J, K N Stevens, Van ‘t Veer, L J, Network, GENICA, A Broeks, A Mannermaa, A Lindblom, L Bernard, Peto, J, dos Santos Silva, I, M Kosel, Bonanni, B., A Jukkola-Vuorinen, Elliott, G., B Burwinkel, L Gibson, Easton, D. F., Yoo, KY, Knight, JA, Z Fredericksen, Grip, M., Gabrieau, V, M J Kerin, Peterlongo, P., Hoover, R N, Beckmann, M.W., J Cerhan, Bogdanova, N., Schürmann, P., Couch, F. J., Yoo, K.Y., R K Schmutzler, Gibson, L, J L Hopper, Lindblom, A, J Benítez, Kosel, M., C M Vachon, G Severi, González Neira, A., Margolin, S., K A Pooley, Humphreys, M. K., Pharoah, P. P., Stevens, K. N., Southey, MC, Brüning, T, Pharoah, PP, Dite, G. S., P Peterlongo, Bartrar, C. R., Elliott, G, A Hein, Kerin, MJ, Yoo, K-Y., Hartikainen, J., Pérez, J. A., R A E M Tollenaar, Dite, G.S., JI Arias Pérez, Garcia-Closas, M, Kosma, VM, Tollenaar, RA, G Chenevix-Trench, Bernard, L., Brock, I. W., Kerin, M J, Pankratz, V S, dos Santos Silva, I., Thomas, G D, J Hartikainen, Stevens, K.N., A M Mulligan, Wang Gohrke, S., Perez, J. I. Arias, Y D Ko, D F Easton, Chanock, S, C A McLean, Humphreys, M.K., M K Schmidt, Gabrieau, V., Arias Pérez, JI, Andrulis, I, Margolin, S, Pankratz, VS, Stevens, KN, Zalutsky, J.V., Ko, Y. D., Mannermaa, A, McLean, C.A., Tollenaar, R. A. E. M., Tollenaar, R.A.E.M., Cox, A., Andrulis, I., Schmutzler, R K, R Hein, Winqvist, R., Cross, S S, Pankratz, V.S., P A Fasching, Chen, X., Easton, D.F., Bernard, L, Ko, Y.D., Pylkäs, K., J Lissowska, Hunter, D. J., Fasching, P. A., Yoo, K. Y., J V Zalutsky, Silva, I.D., Kataja, V., Chenevix-Trench, G., T Brüning, Glendon, G, U Hamann, Hein, R., Thomas, G.D., Van T. Veer, L. J., K Pylkäs, Schmidt, MK, kConFab Investigators, Pérez, JI Arias, Hunter, David, Tollenaar, R A E M +419 morecore +1 more source
