Results 141 to 150 of about 3,686,577 (308)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Breast asymmetry and predisposition to breast cancer [PDF]

, 2006
Introduction It has been shown in our previous work that breast asymmetry is related to several of the known risk factors for breast cancer, and that patients with diagnosed breast cancer have more breast volume asymmetry, as measured from mammograms ...
Lancaster, Gillian, Scutt, Diane, Manning, John T   +2 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Introduction of breast density notification within BreastScreen South Australia – Results of an online client survey

Australian and New Zealand Journal of Public Health
Objective: Breast density is one of the strongest predictors of breast cancer risk and significantly reduces the sensitivity of mammography to detect breast cancer.
Liz Buckley, Carolyn Nickson, Jennifer Stone, Ellen Kerrins, Shona Crabb, David Roder, Michelle Reintals   +6 more
doaj   +1 more source

Heritability of mammographic breast density [PDF]

Quantitative Imaging in Medicine and Surgery, 2020
Evans, D Gareth, van Veen, Elke M, Howell, Anthony, Astley, Susan   +3 more
openaire   +2 more sources

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Efficacy of Ultrasonography in Breast Cancer Screening

Journal of Surgical Ultrasound, 2019
A good screening test should be widely available, inexpensive, and have high sensitivity and specificity. Mammography is the only screening modality proven to reduce the mortality of breast cancer.
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Mammographic Density Estimation: Comparison Between Radiologist’s Visual Assessment and Volpara Breast Density

, 2012
Purpose : To retrospectively compare Volpara mammographic density estimation with the density by radiologists based on the Breast Imaging Reporting and Data System (BI-RADS) density classification.
문희정, 고수연, 김은경, 김민정   +3 more
core  

Breast percent density changes in digital mammography pre‐ and post‐radiotherapy

Journal of Medical Radiation Sciences
Introduction Breast cancer (BC), the most frequently diagnosed malignancy among women worldwide, presents a public health challenge and affects mortality rates.
Sana Mohammadi, Sadegh Ghaderi, Mahdi Mohammadi, Hamid Ghaznavi, Kamal Mohammadian   +4 more
doaj   +1 more source