Results 151 to 160 of about 612,057 (203)

Deep learning prediction of mammographic breast density using screening data. [PDF]

Sci Rep
Chen C, Wang E, Wang VY, Chen X, Feng B, Yan R, Zhu L, Xu D.   +7 more
europepmc   +1 more source

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

Breast density and risk of breast cancer: masking and detection bias. [PDF]

Am J Epidemiol
Lange JM, Gard CC, O'Meara ES, Miglioretti DL, Etzioni R.   +4 more
europepmc   +1 more source

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2. [PDF]

Cancer Epidemiol Biomarkers Prev
Loehrer EA, van der Baan FH, Mooij TM, Andrieu N, Antoniou AC, Dorrius MD, Easton DF, Engel C, Kast K, Mann RM, Noguès C, Schmutzler RK, Tan YY, Eriksson M, van Gils CH, Hooning MJ, Rookus MA, Schmidt MK.   +17 more
europepmc   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

Impact of population based breast density notification: multisite parallel arm randomised controlled trial in BreastScreen.

BMJ
Nickel B, Ormiston-Smith N, Cvejic E, Isautier J, Hammerton L, Baker K, Legerton P, Vardon P, McInally Z, Robertson S, McCaffery K, Houssami N.   +11 more
europepmc   +1 more source

Cross-field strength and multi-vendor reliability of MagDensity for MRI-based quantitative breast density analysis. [PDF]

PLoS One
Ying J, Cattell R, Huang C.
europepmc   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Correlations Between Mammographic Breast Density and Outcomes After Neoadjuvant Chemotherapy in Patients with Locally Advanced Breast Cancer. [PDF]

Cancers (Basel)
Agarwal V, Spalding L, Martin H, Darcey E, Stone J, Redfern A.   +5 more
europepmc   +1 more source