Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad +6 more
wiley +1 more source
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen +16 more
wiley +1 more source
Perceptions of breast cancer risk after breast density notification in a population-based screening program. [PDF]
't Hart D, Marriott R, Stone J.
europepmc +1 more source
Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park +15 more
wiley +1 more source
Machine Learning-Based Approaches for Breast Density Estimation from Mammograms: A Comprehensive Review. [PDF]
Alhusari K, Dhou S.
europepmc +1 more source
Determining Breast Density in Patients with Metabolic Syndrome: A Cross Sectional Study.
Sarvetamin HT.
europepmc +1 more source
Prediction of mammographic breast density based on clinical breast ultrasound images using deep learning: a retrospective analysis. [PDF]
Bunnell A +10 more
europepmc +1 more source
A New Breast Density Assessment Method Using Portable Document Format. [PDF]
Uematsu T +5 more
europepmc +1 more source
Automated Breast Density Assessment for Full-Field Digital Mammography and Digital Breast Tomosynthesis. [PDF]
Jiang S +4 more
europepmc +1 more source
Exploring Dense Breast Density in Mammography: A Comparative Analysis of Breast Cancer Risk. [PDF]
Cardona Ortegón JD +4 more
europepmc +1 more source

