Results 221 to 230 of about 3,686,577 (308)

Obesity and breast density enhance immune exclusion in the primary tumor microenvironment and promote breast cancer metastasis. [PDF]

Oncogene
Williams AE, Hoffmann EJ, Inman DR, Gari MK, Zhou C, Burkel BM, Haidar N, Pan Y, Halambeck M, Moore BN, Wisinski KB, McGregor SM, Kerr SC, Arendt LM, Ponik SM.   +14 more
europepmc   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

A comparison of tumour characteristics of screen-detected and interval cancers and their relationship with breast density and AJCC prognostic stage in a UK screening cohort. [PDF]

Eur Radiol
Kilburn-Toppin F, Rothwell J, Payne NR, Huang Y, Hickman SE, Gilbert FJ.   +5 more
europepmc   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

Agreement Among Breast Cancer Screening Modalities in Breast Density Assessment and Cancer Risk Prediction. [PDF]

Int J Breast Cancer
Aloufi AS, Albeshan SM, Alshabibi AS, Almusined MM, Aldibas LA, Alotaibi MG, Hosawi S.   +6 more
europepmc   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Correction: Association between radiation volume and breast density for skin toxicity and breast edema after radiotherapy in breast conserving therapy of breast cancer. [PDF]

Radiat Oncol
Sonnhoff M, Oyur M, Becker JN, Hermann RM, Carl CO, Nitsche M, Christiansen H, Blach RM.   +7 more
europepmc   +1 more source

The density factor: The enigma of dense breast

World Journal of Nuclear Medicine, 2012
Ajit Padhy, Tian Kok, David Ng
openaire   +3 more sources

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Association Between Baseline Mammographic Breast Density and the Incidence of Natural Menopause in Korean Women: A Nationwide Population-Based Study Using National Health Screening Data. [PDF]

Int J Womens Health
Yoon H, Park JY, Kim C, Shin I, Park JY, Chung YJ, Han K.   +6 more
europepmc   +1 more source