Results 251 to 260 of about 3,686,577 (308)

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Urinary Levels of Endocrine-Disrupting Chemicals and Breast Density in Young Women. [PDF]

Cancer Epidemiol Biomarkers Prev
Carroll JE, Guard HE, March D, Arcaro KF, Huset C, Balasubramanian R, Kontos D, Sturgeon SR.   +7 more
europepmc   +1 more source

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

Advanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui, Yuening Sun, Ziyang Liu, Xuntao Lai, Yunshu Zhao, Yan'er Wang, Yuanming He, Fang Xu, Du Feng, Longlong Liu, Zhenqian Huang, Lijie Xing, Xinliang Mao   +12 more
wiley   +1 more source

STWave: Fine‐Scale Spatial Structure Discovery in Microscopic‐Resolution Spatial Transcriptomics via Patchwise Wavelet Graphs

Advanced Science, EarlyView.
STWave transforms massive microscopic‐resolution spatial transcriptomics into interpretable fine‐scale tissue maps through patch‐wise inference, wavelet‐based multi‐scale encoding, and dual‐domain reconstruction. It reduces noise while preserving weak spatial signals, enabling efficient analysis of 6 40 000 spots of 2.47 GB GPU memory and revealing ...
Tao Jiang, Songming Zhang, Xiaofeng Chen, Xiongtao Xiao, Wenming Cao, Weikai Li, Tong Zhao, Bing Li, Xinyue Xu, Zhongshan Li   +9 more
wiley   +1 more source

Effect of a Real-Time Artificial Intelligence-Assisted Ultrasound System on BI-RADS C4 Breast Lesions Based on Breast Density. [PDF]

Cancers (Basel)
Lee J, Kim WH, Kim J, Kang B, Moon JS, Kim HJ, Lee SJ, Lee IH, Park HY.   +8 more
europepmc   +1 more source

A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle

Advanced Science, EarlyView.
This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin, Weiyan Qi, Lifen Lin, Huilin Zheng, Guoxiang Zhao, Quan Chen, Guoqiang Shao, Yifan Wu, Jialiang Hu, Hanmei Xu   +9 more
wiley   +1 more source

The impact of changes in breast density over time on breast cancer risk. [PDF]

Sci Rep
Kulturoglu MO, Aydin F, Sagdic MF, Aslan F, Oflaz Z, Danisman FB, Kalaylioglu Z, Dogan L.   +7 more
europepmc   +1 more source

Global mammographic asymmetry and short-term breast cancer risk by breast density: a nationwide screening cohort of 5.5 million women. [PDF]

Breast
Lee S, Kim S.
europepmc   +1 more source

Quantitative Changes in Breast Density and Mammographic Features Induced by Pregnancy and Lactation: A Longitudinal Study. [PDF]

J Breast Imaging
Nissan N, Kuten J, Feigin K, Gluskin J, Arita Y, Ochoa Albíztegui RE, Fruchtman-Brot H, Amir T, Reiner JS, Mango VL, Jochelson MS, Sung JS.   +11 more
europepmc   +1 more source

Early thelarche, reproductive hormones, and MRI-based breast density: a prospective study in China. [PDF]

Breast Cancer Res
Li Y, Liu W, Yu Y, Wang Y, Zou L, Liu D, Sun Y.   +6 more
europepmc   +1 more source