Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Data of real-world reference scores for EORTC QLQ-C30 and QLQ-BR23 at baseline in women with early breast cancer and other breast diseases. [PDF]
Data Brief, 2022 Gebert P +4 more
europepmc +1 more source
Macrophagic “Crown-like Structures” Are Associated with an Increased Risk of Breast Cancer in Benign Breast Disease [PDF]
, 2017 Jodi M. Carter +10 more
openalex +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Cirugía oncoplástica en cáncer de mama Oncoplastic surgery in mammary cancer
Revista Colombiana de Cirugía, 2008 El cáncer de mama es la enfermedad maligna más frecuente en la mujer; en el año 2002, se presentaron 209.995 casos nuevos con 42.913 muertes en los Estados Unidos y en Colombia, 5.526 casos nuevos con 2.253 muertes.
Nora Beatriz Sánchez, Jaime Rubiano
doaj
Sophoridine inhibits proliferation and migration by targeting PIM1 in breast cancer
Pharmaceutical BiologyContext Sophoridine, an alkaloid quinolizidine derived from Sophora flavescens Aiton (Fabaceae), has strong anti-tumor activity in a variety of malignancies. Nevertheless, the effects and underlying mechanism of sophoridine on breast cancer are not fully
Lu Chen +7 more
doaj +1 more source
A CASE OF RIGHT BREAST CANCER WITH VON RECKLINGHAUSEN'S DISEASE
, 1992 Masashi Okamoto +4 more
openalex +2 more sources
Nurses\u27 Health Study: Demonstrating the impact of research, and adapting new measures and approaches to increase relevance and effect of cohort studies [PDF]
, 2016 Colditz, Graham A
core +2 more sources
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
Enhanced AkaLuc Bioluminescence Imaging for Longitudinal Intravital Monitoring of Minimal Residual Disease in a Murine Model of Triple-negative Breast Cancer [PDF]
Silvia Steinbauer +9 more
openalex +1 more source