Results 151 to 160 of about 2,794,152 (377)
Interpretable PROTAC Degradation Prediction With Structure‐Informed Deep Ternary Attention Framework
PROTAC‐STAN, a structure‐informed deep learning framework is presented for interpretable PROTAC degradation prediction. By modeling molecular hierarchies and protein structures, and simulating ternary interactions via a novel attention network, PROTAC‐STAN achieves significant performance gains over baselines.
Zhenglu Chen +11 more
wiley +1 more source
Background: Breast feeding is one of the most important determinants of child survival, birth spacing and prevention of childhood infections. It is important for the Anganwadi workers to have adequate scientific knowledge about breast feeding practices.
Sultan Rizwan Ahmad +2 more
doaj
Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu +9 more
wiley +1 more source
Background: Breast milk is the only food fully adapted to the physiology of human infants. Optimal breastfeeding is defined as initiating breastfeeding immediately after birth exclusively breastfeeding until 6 months of infant age, and continuing ...
Kareem Assi Obaid
doaj +2 more sources
Background: Placing I.U.D is a very effective method in the prevention of pregnancy, which has increasingly became popular. Women have found it an effective, safe and comfortable method all over the world.
Ghorbani, S +3 more
doaj
PS-054 Vsl#3 Supplementation To Mothers During Pregnancy And Breast Feeding Improves Colics And Regurgitation In Newborns, Perhaps By Tgf-b Modulation [PDF]
Maria Elisabetta Baldassarre +6 more
openalex +1 more source
B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang +16 more
wiley +1 more source
Introduction. In spite of high physiologic ability of lactation in mothers, most of them have not cooperation for breast feeding. Mothers' knowledge and attitude are important for lactation behavior.
M HASHEMIPOOR +8 more
doaj
The VHL‐HIF2α (VHL is Von Hippel‐Lindau) axis in adipocytes differentially regulates hematopoiesis and bone formation through stem cell factor (SCF) and chemerin, respectively. This hypoxia‐responsive pathway in adipocytes establishes a systemic signaling network with HSCs and MSCs to maintain tissue homeostasis, revealing a targetable axis for ...
Qian Li +6 more
wiley +1 more source

