Results 41 to 50 of about 313,717 (307)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A review of the immunomodulating components of maternal breast milk and protection against necrotizing enterocolitis [PDF]

, 2019
Breast milk contains immunomodulating components that are beneficial to newborns during maturation of their immune system. Human breast milk composition is influenced by an infant\u27s gestational and chronological age, lactation stage, and the mother ...
Fiorentino, Jinquan, Lila S. Nolan, Misty Good, Moe-Byrne, Olivia B. Parks   +5 more
core   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Breast-feeding practices and maternal employment in health facilities of Lira District, Northern Uganda

Bulletin of the National Research Centre, 2022
Background In Uganda, many working mothers stop breast-feeding before the end of the mandatory maternity leave of 60 days. Inadequate breast-feeding is a risk factor for infant morbidity and mortality.
Tom Omute, Gloria Kirungi
doaj   +1 more source

Association of economic status with breastfeeding rates in Northern Iran. [PDF]

, 2012
To assess the breast-feeding condition based on economic status among primary school children and comparison between Turkman and non-Turkman ethnic groups in northern Iran in 2010. This was a descriptive, cross-sectional and retrospective research study,
Veghari, G.
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Expressing yourself: A feminist analysis of talk around expressing breast milk [PDF]

, 2009
Recent feminist analyses, particularly from those working within a poststructuralist framework, have highlighted a number of historically located and contradictory socio-cultural constructions and practices which women are faced with when negotiating ...
Sally Johnson, Iain Williamson, Steven Lyttle, Dawn Leeming, Baranowski, Barclay, Bartlett, Bartlett, Bartlett, Blum, Blyth, Bolling, Carter, Cooper, Davies, Dennis, Department for Work and Pensions, Dykes, Dykes, Dyson, Earle, Eyer, Frosh, Furber, Furber, Galtry, Gatrell, Gavey, Grosz, Guttman, Hauck, Hausman, Hays, Kelleher, Marshall, Maushart, McCarter-Spaulding, Morse, Mozingo, Murphy, Murphy, Papinczak, Parker, Parker, Parker, Schaffer, Schmied, Schmied, Shaw, Shaw, Spencer, Stainton Rogers, Stearns, Ussher, Van Esterik, Wall, Weedon, Wetherell, Willig, Wolf   +59 more
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Mother–infant interactions and infant intake during breastfeeding versus bottle‐feeding expressed breast milk

Maternal and Child Nutrition, 2021
Bottle‐fed infants are at higher risk for rapid weight gain compared with breastfed infants. Few studies have attempted to disentangle effects of feeding mode, milk composition and relevant covariates on feeding interactions and outcomes.
Alison Ventura, Megan Hupp, Joseph Lavond   +2 more
doaj   +1 more source

Time trends in the prevalence and determinants of age-appropriate breast feeding among children aged 0–23 months in Ghana: a pooled analysis of population-based surveys, 2003–2017

BMJ Open, 2022
Objective We assessed the sociodemographic and maternal–child characteristics associated with age-appropriate breast feeding among children aged 0–23 months in Ghana.Methods We pooled data on 12 743 children aged 0–23 months from three Demographic and ...
Clara Calvert, Judith R Glynn, Laura L Oakley, Milly Marston, Shamsudeen Mohammed   +4 more
doaj   +1 more source