Results 81 to 90 of about 124,132 (312)
SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease
SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi+11 more
wiley +1 more source
Difficulties Associated with Breast-feeding [PDF]
F. E. Hytten+2 more
openalex +1 more source
In CLas‐infected D. citri, CLas lowers 20E levels initially, relieving the suppression of ETH release. The subsequent increase in ETH levels upregulates its receptor DcETHR and activates the JH signaling pathway. The signaling cascade of 20E‐ETH/ETHR‐JH along with miR‐210, targeting DcETHR, boost female fecundity in CLas+ D.
Xiaoge Nian+8 more
wiley +1 more source
Corramycin is a novel natural product produced by the myxobacterium Corallococcus coralloides. The structure, extraordinary total synthesis and biosynthesis of the antibiotic is described for the first time. Its promise as an in vivo septicemia model, the absence of cross‐resistance with commonly used antibiotic classes, and the lack of cytotoxicity ...
Cédric Couturier+32 more
wiley +1 more source
In order of assess the results of introduction of the programs aimed at maintenance and support of the breast-feeding it is necessary to use uniform indicators, which guarantee consistency, reliability and comparability of the data.
L. V. Abol'yan+2 more
doaj +1 more source
Spatially resolved multiomics reveals that high‐copper zones are closely associated with tumor metastasis, immune‐desert phenotypes, and oxidative‐phosphorylation (OXPHOS)‐dependent proliferation. A targeted bacterial nanovesicle delivering copper‐depleting agents effectively reduces tumor copper levels, inhibits OXPHOS‐dependent tumor growth, and ...
Lin Chen+16 more
wiley +1 more source
HIPPURIC ACID IN THE URINE OF NORMAL BREAST-FEED INFANTS [PDF]
Samuel Amberg
openalex +1 more source
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang+10 more
wiley +1 more source
Accessible ecophysiological tools for seabird conservation
Abstract Seabirds are the most endangered avian taxa on Earth, with over a third of species globally threatened. To help slow their decline, conservation physiology seeks to determine how seabird responses to climatic and anthropogenic threats influence demographic processes, but it is not widely utilized in monitoring.
Edin A. Whitehead, Brendon J. Dunphy
wiley +1 more source
Simulation of breast compression using a new biomechanical model [PDF]
Mammography is currently the primary imaging modality for breast cancer screening and plays an important role in cancer diagnostics. A standard mammographic image acquisition always includes the compression of the breast prior x-ray exposure. The breast is compressed between two plates (the image receptor and the compression paddle) until a nearly ...
arxiv