Results 121 to 130 of about 1,018,704 (304)

Versatile Co‐Engineering of Immunogenic Cell Death‐Primed Dead Tumor Cell Bodies With Tumor‐Activated MnO2 for cGAS‐STING‐Potentiated Personalized Immunotherapy

Advanced Science, EarlyView.
DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu, Xuan Lu, Yuquan Wang, Haihua Ji, Ying Zhang, Yiqun Wan, Hao Wan   +6 more
wiley   +1 more source

Aumento mamário por meio da incisão da abdominoplastia: estudo prospectivo de 100 casos

Revista Brasileira de Cirurgia Plástica
INTRODUÇÃO: A gravidez e a obesidade causam distensão da parede abdominal e também produzem mudanças na forma e no tamanho das mamas. Assim, não é incomum a necessidade de melhoria estética da área abdominal, coincidindo com o desejo de aumento de mama ...
Gal Moreira Dini, Jean Milani, Luciana Gianini Albuquerque, Mario Farinazzo de Oliveira, Ivan Dunshee de Abranches Oliveira Santos Filho, Lauren Klas Iurk, Lydia Masako Ferreira   +6 more
doaj   +1 more source

Breast implant illness after reconstruction with silicone breast implants

JNCI: Journal of the National Cancer Institute
Abstract Background “Breast implant illness” (BII) is a constellation of non-specific constitutional, rheumatologic, mental, and cognitive symptoms reported increasingly by women carrying silicone breast implants (SBIs).
Jonathan Spoor, Marc A M Mureau, Renaud L M Tissier, Juliëtte Hommes, Hinne Rakhorst, Mintsje de Boer, Hester S A Oldenburg, Esther M Heuts, Yvonne L J Vissers, Anneriet E Dassen, Daniel J Evers, Linetta B Koppert, Laura H Zaal, Sabine C Linn, Daphne de Jong, Rene R W J van der Hulst, Marie-Jeanne T F D Vrancken Peeters, Eveline M A Bleiker, Flora E van Leeuwen   +18 more
openaire   +7 more sources

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

Advanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui, Yuening Sun, Ziyang Liu, Xuntao Lai, Yunshu Zhao, Yan'er Wang, Yuanming He, Fang Xu, Du Feng, Longlong Liu, Zhenqian Huang, Lijie Xing, Xinliang Mao   +12 more
wiley   +1 more source

Report from the 'Eccles' breast screening programme Dublin on epidemiological aspects of screening for breast cancer in Ireland

, 1995
This report outlines the major epidemiological aspects of screening for breast cancer, drawing extensively on experience accrued at the ECCLES Breast Screening Programme over 5 years. It is not an exhaustive account of all aspects of screening.
Codd, Mary B
core  

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

Level III axillary lymph nodes involvement in node positive breast cancer received neoadjuvant chemotherapy

, 2013
Objective: To investigate the incidence, associated factors and prognosis of level III node involvement for breast cancer with positive axillary lymph nodes after neoadjuvant chemotherapy.
Wang, Tianfeng, Li, Jinfeng, Xie, Yuntao, Fan, Tie, Fan, Zhaoqing, Lin, Benyao, Ouyang, Tao   +6 more
core   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

INTRAPEC Technique Controls Pectoralis Spasm and Pain for Subpectoral Breast Implantation: A Retrospective Study. [PDF]

Plast Reconstr Surg Glob Open, 2020
Kline J, Lee W, Wofford K.
europepmc   +1 more source