Results 191 to 200 of about 60,742 (289)

Don't judge an implant by its cover: how the foreign body response and fibrotic capsule might be harnessed for good. [PDF]

NPJ Biomed Innov
Dickenson ME, Oakes RS, Morris AH.
europepmc   +1 more source

Breast Implants–Current Insights on a Common Medical Device

, 2016
Umar Choudry
openalex   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Venous Port implantation in persistent left superior vena cava with azygos vein variation: a case report and literature review. [PDF]

BMC Surg
Zhang L, Wu J.
europepmc   +1 more source

Compliant, Tough,Fatigue-Resistant, and BiocompatiblePHEMA-Based Hydrogels as a Breast Implant Material

Yi He (408132), Qianqian Liang (1521904), Qin Liu (59805), Hongyi Lv (4391371), Wanting Yuan (19871736), Ziqi Wang (1525060), Yong Liu (6908), Jinrong Wu (2036902), Lijuan Zhao (1387689), Yi Wang (32470)   +9 more
openalex   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

3D printed, biodegradable, and biocompatible intraperitoneal implants loaded with folic acid-targeted/pH-sensitive/doxorubicin-loaded hydroxyapatite nanoparticles for systemic treatment of metastatic breast cancer. [PDF]

J Nanobiotechnology
Kefayat A, Molaabasi F, Bahrami M, Karami M, Mirzadeh M, Askari E, Hajian A, Gharemani F, Mirzavandi Z, Rafienia M, Poursamar SA.   +10 more
europepmc   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

When to remove implantable vascular access ports? a retrospective analysis of 376 patients with breast cancer and implantable vascular access ports. [PDF]

BMC Surg
Luo J, Yao Z, Liang W, Zhao G, Zheng J, Liu Y, Jiang Z, Yu X.   +7 more
europepmc   +1 more source