Results 61 to 70 of about 26,753 (256)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Comparison of the diagnostic performance of Quantra artificial intelligence software with an experienced radiologist in the mammographic breast density assessment in women with and without breast implants

Journal of the Mexican Federation of Radiology and Imaging
Mammographic sensitivity decreases when mammographic breast density (MBD) is assessed in women with dense breasts and/or breast implants. This study compared the diagnostic performance of Quantra artificial intelligence (AI) software with an experienced ...
Beatriz E. Gonzalez-Ulloa, Claudia B. Corona-Gonzalez, Rosa L. Molina-Gutierrez   +2 more
doaj   +1 more source

Quality of life and aesthetic results after mastectomy and mammary reconstruction [PDF]

Revista Brasileira de Cirurgia Plástica, 2019
Introduction: Due to the increased incidence of breast cancer, the demand for breast reconstruction has been increasing, along with concerns regarding the satisfaction and quality of life of the patients.
Marcela Caetano Cammarota, Amanda Costa Campos, Cesar Augusto Daher Ceva Faria, Gabriel Campelo dos-Santos, Leonardo David Pires Barcelos, Ronan Caputi Silva Dias, Fabrício Tavares Mendonça, Jose Carlos Daher   +7 more
doaj   +1 more source

Breast Implants and Radiation

Seminars in Plastic Surgery, 2019
AbstractOne of the most influential factors in the success of breast reconstruction is whether or not radiation therapy has or will be performed. While traditional teaching is that all breasts treated with radiation therapy must be reconstructed with an autologous component, many reconstructive surgeons perform implant-based breast reconstruction ...
Alexander F, Mericli, Safa E, Sharabi
openaire   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

What can we learn from sonication results of breast implants?

PLoS ONE, 2017
BackgroundDifferent research groups have identified microorganisms on breast implants by sonication with significant correlation to the rate of capsular contracture.
Frederike M J Reischies, Robert Krause, Judith Holzer, Fabian Tiefenbacher, Raimund Winter, Gertraud Eylert, Tobias Meikl, Alexandru Tuca, Martin J Köfer, Lars P Kamolz, David B Lumenta   +10 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Breast implant illness in silicone breast implant patients [PDF]

, 2022
This dissertation studied health complaints in Silicone Breast Implant (SBI) patients, known under the term Breast Implant Illness (BII). This is a symptom complex of non-specific health complaints such as muscle pain, joint pain, extreme fatigue, sleep disturbances, pyrexia, dry eyes/dry mouth (sicca) and cognitive disturbances.
openaire   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source