Results 141 to 150 of about 1,744,838 (315)

Endocrine and metabolic response in the human newborn to first feed of breast milk. [PDF]

, 1977
A Aynsley‐Green, S.R. Bloom, D H Williamson, R. C. Turner   +3 more
openalex   +1 more source

GLUL Confers Perivascular Cancer‐Associated Fibroblasts With Pro‐Angiogenic Capacity to Promote Glioma Progression

Advanced Science, EarlyView.
Schematic illustration of the proposed model. Primary CAFs are isolated from fresh human GBM specimens according to established protocols. GLUL is essential for pro‐angiogenic capacity of CAFs through its impact on the PI3K/AKT pathway. GLUL enhances the pro‐angiogenic capacity of CAFs, driving aberrant tumor vasculature that fuels tumor growth ...
Qing Zhang, Yida Liu, Zhi Zhang, Yang Wang, Fusheng Liu   +4 more
wiley   +1 more source

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

Iodine status of breastfed infants and their mothers' breast milk iodine concentration [PDF]

, 2020
Erna Petersen, Birna Þórisdóttir, Inga Þórsdóttir, Geir Gunnlaugsson, Petra Arohonka, Iris Erlund, Ingibjörg Gunnarsdóttir   +6 more
openalex   +1 more source

Surface‐Associated Proteins on Extracellular Vesicles Remodel the Tumor Microenvironment by Potentiating TGF‐β Signaling in a Contact‐Dependent Manner

Advanced Science, EarlyView.
Extracellular vesicles (EVs) released from TGF‐β‐activated CAFs are enriched with ECM proteins such as TSG6 and THBS1, which facilitate their binding to recipient cell membranes. This EV–cell interaction promotes the clustering of CD44 and TGF‐β receptors on the target cell surface, thereby potentiating TGF‐β signaling activity. This study highlights a
Chao Li, Agustin Enciso‐Martinez, Lizhe Zhu, Sarah A. Rotman, Peter A. van Veelen, Roman I. Koning, Hailiang Mei, Peter ten Dijke   +7 more
wiley   +1 more source

Factors Affecting Breast Milk Substitute in Pidie Jaya, Aceh, Indonesia

Althea Medical Journal
Background: Breast milk is the first, main, and best natural food for babies. Breast milk contains various nutrients needed in the process of growth and development of babies. Breastfeeding is a health behavior carried out by mothers. This study aimed to
Frisca Fazira, Nita Arisanti, Dida Gurnida, Hadi Susiarno, Muhammad Alamsyah Azis, Kusnandi Rusmil   +5 more
doaj   +1 more source

Figure S3 from Early-Stage Breast Cancer Detection in Breast Milk [PDF]

Cristina Saura, Carolina Ortiz, Judit Matito, Enrique J. Arenas, Anna Suñol, Ágatha Martín, Octavi Córdoba, Alex Martínez-Sabadell, Itziar García-Ruiz, Ignacio Miranda, Clara Morales-Comas, Estela Carrasco, Cristina Viaplana, Vicente Peg, Paolo Nucíforo, Neus Bayó-Puxan, Alberto González‐Medina, Josep M. Miquel, Marina Gómez-Rey, Guillermo Villacampa, Sílvia Arévalo, Martín Espinosa-Bravo, Judith Balmañà, Rodrigo Dienstmann, Joaquı́n Arribas, Josep Tabernero, Ana Vivancos, Miriam Sansó   +27 more
openalex   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Human Immunodeficiency Virus-Specific CD8⁺T Cells in Human Breast Milk

, 2002
Steffanie Sabbaj, Bradley H. Edwards, Mrinal K. Ghosh, Katherine Semrau, Sanford Cheelo, Donald M. Thea, Louise Kuhn, Gerd Ritter, Mark J. Mulligan, Paul A. Goepfert, Grace M. Aldrovandi   +10 more
openalex   +1 more source

Behavior‐ and Cell Type‐Specific Cortico‐Striatal Decoupling in a Parkinson's Disease‐Like Mouse Model

Advanced Science, EarlyView.
Utilizing dual‐site fiber photometry, this study examines cortico‐striatal coupling with cell type resolution, identifying behavior‐ and cell type‐specific cortico striatal decoupling and its dopamine‐dependent mechanism in a Parkinson's disease mouse model.
Xu‐Ran Yao, Yang Liu, Wei‐Tong Zheng, Mao‐Qing Huang, Kai‐Wen He   +4 more
wiley   +1 more source