Results 261 to 270 of about 1,896,405 (407)
Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine
A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li+14 more
wiley +1 more source
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang+13 more
wiley +1 more source
Our study focused exclusively on adequacy of nutrient intake and the determinants of overall diet quality among lactating women of rural Bangladesh from a population‐weighted, nationally representative large sample. The diet of most lactating women of rural Bangladesh indicates the inadequacy of several micronutrients especially riboflavin, calcium ...
Saiful Islam+4 more
wiley +1 more source
Estimation of 24 h breast-milk fat concentration and fat intake in rural northern Thailand [PDF]
Dorothy A. Jackson+7 more
openalex +1 more source
During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li+15 more
wiley +1 more source
Long‐term probiotics' consumption (≥8 weeks) had a beneficial effect on office and ambulatory blood pressure (BP), especially in the diabetes and hypertension, and the changes in BP were not associated with the increase of age, body mass index (BMI), and treatment duration.
Tian‐Xue Zhao+5 more
wiley +1 more source